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70 results for " Antagonists" - showing 1-50
Kinase A Inactive holoenzyme type 2 alpha, Active Protein (Cat# AAA142751)
Full Name
Recombinant Protein Kinase A Inactive holoenzyme type 2 alpha
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
$3,840/0.1 mg | $180/0.001 mg | $250/0.003 mg | $17,055/5x0.1 mg
Western Blot (WB)
(All lanes : Anti-ADRA2B Antibody (Center) at 1:1000 dilutionLane 1: MCF-7 whole cell lysateLane 2: MDA-MB-231 whole cell lysateLane 3: SK-BR-3 whole cell lysate Lysates/proteins at 20 ug per lane.Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.Predicted band size : 50 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
ADRA2B, Polyclonal Antibody (Cat# AAA9213197)
Full Name
ADRA2B Antibody (Center)
Gene Names
ADRA2B; FAME2; ADRA2L1; ADRARL1; ADRA2RL1; ALPHA2BAR; alpha-2BAR
Reactivity
Human
Applications
WB, EIA, IHC-P, FC/FACS, IF
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Growth hormone antagonists, Active Protein (Cat# AAA400126)
Full Name
Rat growth hormone antagonists (G119R)
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC.
(b) Gel filtration at non denaturing conditions using 25 nM Tris-HCl + 300 nM NaCl, pH 8.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
(b) Gel filtration at non denaturing conditions using 25 nM Tris-HCl + 300 nM NaCl, pH 8.
(c) Analysis by reducing and non-reducing SDS-PAGE Silver Stained gel.
Pricing
$175/0.01 mg | $260/0.05 mg | $360/0.1 mg | $980/0.5 mg | $1,680/1 mg | $6,530/5 mg | $11,060/10 mg
Pegylated leptin antagonist, Active Protein (Cat# AAA400095)
Full Name
Pegylated ovine leptin antagonist (mutant L39A/D40A/F41A)
Gene Names
LEP; OB; OBS; LEPD
Purity
The purity of recombinant ovine pegylated leptin antagonist is greater than 95.0% as determined by:
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
(a) Gel filtration analysis.
(b) Analysis by reducing and non-reducing SDS-PAGE gel.
Pricing
$250/0.05 mg | $360/0.1 mg | $1,210/0.5 mg | $1,960/1 mg | $7,455/5 mg | $12,795/10 mg
Activity Data
(Figure. Cell proliferation of A549 cells after stimulated with GREM1.Gremlin (GREM1) is an inhibitor in the TGF beta signaling pathway. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. A proliferation assay was conducted to detect the bioactivity of recombinant mouse GREM1 using A549 cells. Briefly, A549 cells were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of GREM1. After incubated for 96h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly,10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Proliferation of A549 cells after incubation with GREM1 for 96h observed by inverted microscope was shown in Figure1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8) assay after incubation with recombinant GREM1 for 96h. The result was shown in Figure 2. It was obvious that GREM1 significantly increased cell viability of A549 cells.(A) A549 cells cultured in DMEM, stimulated with 1ng/mL GREM1 for 96h; (B) Unstimulated A549 cells cultured in DMEM for 96h.)
Gremlin 1 (GREM1), Active Protein (Cat# AAA2105166)
Full Name
Active Gremlin 1 (GREM1)
Gene Names
Grem1; ld; Drm; Grem; Cktsf1b1
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$205/0.01 mg | $405/0.05 mg | $625/0.1 mg | $770/0.2 mg | $1,495/0.5 mg | $2,225/1 mg | $5,435/5 mg
Protein Kinase A, Holoenzyme Type 2a, Active Protein (Cat# AAA636014)
Full Name
Protein Kinase A, Holoenzyme Type 2a, Recombinant (PKA)
Purity
Highly Purified
95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
Pricing
$365/0.001 mg | $515/0.003 mg | $2,305/5x0.003 mg
Leptin Triple Antagonist, Active Protein (Cat# AAA143655)
Full Name
Recombinant Ovine Leptin Triple Antagonist, Pegylated
Purity
Greater than 95.0% as determined by: (a) Gel filtration analysis. (b) Analysis by SDS-PAGE.
Pricing
$760/0.05 mg | $1,070/0.1 mg | $5,300/1 mg | $23,620/5x1 mg
Protein Kinase A, Holoenzyme Type 1a, Active Protein (Cat# AAA636992)
Full Name
Protein Kinase A, Holoenzyme Type 1a, Recombinant (PKA)
Purity
Highly Purified
95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
95% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.
Pricing
$365/0.001 mg | $515/0.003 mg | $2,305/5x0.003 mg
Western Blot (WB)
(Western blot analysis of P2RY1 using COLO205 whole cell lysates)
P2RY1, Polyclonal Antibody (Cat# AAA9603116)
Full Name
P2RY1 Antibody
Gene Names
P2RY1; P2Y1; SARCC
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Activity Data
(Figure. Cell proliferation of A549 cells after stimulated with GREM1.Gremlin (GREM1) is an inhibitor in the TGF beta signaling pathway. GREM1 and other BMP antagonists are important in the survival of cancer stroma survival and proliferation in some cancers. The protein expression is found in many cancers and is thought to play important roles in uterine cervix, lung, ovary, kidney, breast, colon, pancreas, and sarcoma carcinomas. A proliferation assay was conducted to detect the bioactivity of recombinant human GREM1 using A549 cells. Briefly, A549 cells were seeded into triplicate wells of 96-well plates at a density of 5,000 cells/well and allowed to attach, replaced with serum-free overnight, then the medium was replaced with 2% serum standard DMEM prior to the addition of various concentrations of GREM1. After incubated for 96h, cells were observed by inverted microscope and cell proliferation was measured by Cell Counting Kit-8 (CCK-8). Briefly, 10uL of CCK-8 solution was added to each well of the plate, then the absorbance at 450nm was measured using a microplate reader after incubating the plate for 1-4 hours at 37 degree C. Proliferation of A549 cells after incubation with GREM1 for 96h observed by inverted microscope was shown in Figure 1. Cell viability was assessed by CCK-8 (Cell Counting Kit-8) assay after incubation with recombinant GREM1 for 96h. The result was shown in Figure 2. It was obvious that GREM1 significantly increased cell viability of A549 cells.(A) A549 cells cultured in DMEM, stimulated with 1ng/mL GREM1 for 96h; (B) Unstimulated A549 cells cultured in DMEM for 96h.)
Gremlin 1 (GREM1), Active Protein (Cat# AAA2105165)
Full Name
Active Gremlin 1 (GREM1)
Gene Names
GREM1; DRM; HMPS; MPSH; PIG2; CRAC1; CRCS4; DAND2; HMPS1; IHG-2; DUP15q; C15DUPq; GREMLIN; CKTSF1B1
Applications
Cell Culture, Activity Assays
Purity
> 97%
Pricing
$195/0.01 mg | $390/0.05 mg | $600/0.1 mg | $735/0.2 mg | $1,425/0.5 mg | $2,120/1 mg | $5,215/5 mg
Western Blot
(Western Blot analysis using CER1 antibodyWestern Blot showing CER1 antibody used against CER1 (aa18-267)-hIgGFc transfected HEK293 cell lysate (1).)
CER1, Monoclonal Antibody (Cat# AAA831099)
Full Name
CER1 antibody
Applications
EIA, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Western Blot (WB)
(Western Blot showing CER1 antibody used against CER1 (aa18-267)-hIgGFc transfected HEK293 cell lysate (1).)
CER1, Monoclonal Antibody (Cat# AAA533358)
Full Name
CER1 antibody
Applications
EIA, IHC, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Follistatin, Active Protein (Cat# AAA538118)
Full Name
Follistatin protein
Gene Names
Fst; FS; AL033346
Applications
User optimized
Purity
> 95% pure
Pricing
$425/0.02 mg | $1,905/5x0.02 mg
AGTR1, Polyclonal Antibody (Cat# AAA534078)
Full Name
AGTR1 antibody
Reactivity
Rat
Applications
EIA, IHC, IF, WB
Purity
AGTR1 antibody was purified by affinity chromatography.
Pricing
$885/0.1 mg | $3,970/5x0.1 mg
Noggin, Active Protein (Cat# AAA539560)
Full Name
Noggin protein (Mouse)
Gene Names
NOG; SYM1; SYNS1
Applications
User optimized
Purity
> 95% pure
Pricing
$425/0.02 mg | $1,905/5x0.02 mg
Noggin, Recombinant Protein (Cat# AAA539588)
Full Name
Noggin protein
Gene Names
NOG; SYM1; SYNS1
Applications
User optimized
Purity
> 95% pure
Noggin, Active Protein (Cat# AAA539493)
Full Name
Noggin protein
Gene Names
NOG; SYM1; SYNS1
Applications
User optimized
Purity
> 98% pure
Pricing
$425/0.02 mg | $1,905/5x0.02 mg
AT1R, Polyclonal Antibody (Cat# AAA534545)
Full Name
AT1R antibody
Reactivity
To be determined by end-user
Applications
EIA, WB
Purity
Protein G affinity chromatography
AGTR1, Polyclonal Antibody (Cat# AAA534801)
Full Name
AGTR1 antibody
Gene Names
AGTR1; AT1; AG2S; AT1B; AT1R; AT1AR; AT1BR; AT2R1; HAT1R; AGTR1B
Reactivity
Rat
Applications
EIA, IHC, IF, WB
Purity
AGTR1 antibody was purified by affinity chromatography.
Pricing
$885/0.1 mg | $3,970/5x0.1 mg
TSG, Active Protein (Cat# AAA539380)
Full Name
TSG protein
Applications
User optimized
Purity
> 98% pure
Pricing
$425/0.05 mg | $1,905/5x0.05 mg
Follistatin, Polyclonal Antibody (Cat# AAA535695)
Full Name
Follistatin antibody
Gene Names
Fst; FS; AL033346
Reactivity
Human follistatin
Applications
EIA, WB
Pricing
$425/0.05 mg | $1,905/5x0.05 mg
NMDAR NR2B, Polyclonal Antibody (Cat# AAA221313)
Full Name
RABBIT ANTI NMDA RECEPTOR NR2B (pTyr1472)
Gene Names
Grin2b; GluN2B
Reactivity
Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human (Expected from Sequence), Monkey (Expected from Sequence), Mouse (Expected from Sequence), Zebrafish (Expected from Sequence)
Applications
WB
Pricing
$625/0.1 mL | $2,670/5x0.1 mL
Western Blot (WB)
(SLC22A1 Antibody (C-term) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC22A1 antibody detected the SLC22A1 protein (arrow).)
SLC22A1, Polyclonal Antibody (Cat# AAA9208382)
Full Name
SLC22A1 Antibody (C-term)
Gene Names
SLC22A1; OCT1; HOCT1; oct1_cds
Reactivity
Human
Applications
WB, EIA, IHC-P
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Angiotensin-Converting Enzyme 2 (ACE2), Cell Line (Cat# AAA434276)
Full Name
Human Angiotensin-Converting Enzyme 2 (hACE2) Stable Cell Line
Pricing
$5,250/1 Each
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant DAND5 protein (Right) or empty vector (Left) detected with DAND5 antibody)
DAND5, Monoclonal Antibody (Cat# AAA533877)
Full Name
DAND5 antibody
Gene Names
DAND5; SP1; CER2; COCO; CRL2; CERL2; DANTE; GREM3; CKTSF1B3
Applications
FC/FACS, IHC, WB
Purity
DAND5 antibody was purified by affinity chromatography.
Pricing
$885/0.1 mL | $3,965/5x0.1 mL
NMDAR NR2B, Polyclonal Antibody (Cat# AAA221522)
Full Name
RABBIT ANTI NMDA RECEPTOR NR2B (pTyr1252)
Gene Names
Grin2b; GluN2B
Reactivity
Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Zebrafish (Expected from Sequence)
Applications
WB
Pricing
$625/0.1 mL | $2,670/5x0.1 mL
Testing Data
Delta-type opioid receptor (OPRD1), Cell Line (Cat# AAA430278)
Full Name
Human Delta-type opioid receptor (OPRD1) ACTOne Stable Cell Line
Gene Names
OPRD1; DOP; DOR; DOR1; OPRD
Testing Data
Muscarinic Acetylcholine Receptor M4 (CHRM4), Cell Line (Cat# AAA430349)
Full Name
Muscarinic Acetylcholine Receptor M4 (CHRM4) ACTOne Stable Cell Line
Gene Names
CHRM4; HM4; M4R
Testing Data
G-protein coupled receptor 119 (GPR119), Cell Line (Cat# AAA430275)
Full Name
Human G protein-coupled receptor 119 (GPR119) ACTOne Stable Cell Line
Gene Names
GPR119; GPCR2
Testing Data
5-Hydroxytryptamine (Serotonin) Receptor 1F (HTR1F), Cell Line (Cat# AAA430277)
Full Name
Human 5-hydroxytryptamine (serotonin) receptor 1F (HTR1F) ACTOne Stable Cell Line
Gene Names
HTR1F; 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F
Testing Data
5-Hydroxytryptamine (Serotonin) Receptor 1A (HTR1A), Cell Line (Cat# AAA430276)
Full Name
Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A) ACTOne Stable Cell Line
Gene Names
HTR1A; G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1
Flow Cytometry (FC/FACS)
(Staining of normal human peripheral blood cells with CD281 antibody vs. Purified Mouse IgG1 Isotype Control. Cell sin the monocyte gate were used for analysis.)
Toll-like receptor 1, Monoclonal Antibody (Cat# AAA832906)
Full Name
Toll-like receptor 1 antibody
Gene Names
TLR1; TIL; CD281; rsc786; TIL. LPRS5
Applications
Functional Assay
Purity
Toll-like receptor 1 antibody was purified by affinity chromatography.
Pricing
$365/0.025 mg | $1,635/5x0.025 mg
Flow Cytometry (FC/FACS)
(Staining of normal human peripheral blood cells with Mouse IgG1 kappa Isotype Control (PE) (open histogram) or CD281 antibody (PE) (filled histogram). Cells in the monocyte gate were used for analysis.)
Toll-like receptor 1, Monoclonal Antibody (Cat# AAA832070)
Full Name
Toll-like receptor 1 antibody (PE)
Gene Names
TLR1; TIL; CD281; rsc786; TIL. LPRS5
Applications
FC/FACS
Pricing
$495/25 Tests | $2,230/5x25 Tests
CCKA, Polyclonal Antibody (Cat# AAA834662)
Full Name
CCKA Receptor antibody
Applications
IHC
Pricing
$1,010/0.05 mL | $4,535/5x0.05 mL
Luteinizing Hormone/Choriogonadotropin, Cell Line (Cat# AAA430195)
Full Name
Human Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) ACTOneTM Stable Cell Line
Neuropeptide Y Receptor Y5, Cell Line (Cat# AAA430196)
Full Name
Neuropeptide Y Receptor Y5 (NPY5R) ACTOneTM Stable Cell Line
Gene Names
NPY5R; NPYR5; NPY5-R; NPYY5-R
Testing Data
(Figure 1. Response of ACTOne GPBAR1 (TGR5) cell line & parental cell line to LCA. ACTOne GPBAR1 cells and parental cells were plated overnight in 20 ul culture medium on a BD Biocoat 384 well plate. The next day, cells were dye-loaded with 20 ul/well of 1X Dye-loading solution (Membrane Potential Assay Kit). After 2 hours of incubation at room temperature, two readings were obtained prior to and 30 min after the addition of LCA. Ratios of the two readings (F/F0) are plotted in the figure. A. Dose response curve of LCA in ACTOne TGR5 cell line. EC50 = 3.2 uM in the presence of PDE inhibitor. B. Parental cells do not respond to LCA)
G-protein coupled bile acid receptor 1 (GPBAR1), Cell Line (Cat# AAA430274)
Full Name
Human G-protein-coupled bile acid receptor 1 (GPBAR1) ACTOne Stable Cell Line
Gene Names
GPBAR1; BG37; TGR5; M-BAR; GPCR19; GPR131
Western Blot (WB)
(Figure A. Representative image of western blot with ACE2 and TMPRSS2 antibody.1) Cell lysate from HEK293-ACE2-TMPRSS2 cells ("ACE2-TMPRSS2", Catalog # MBS434319);2) Cell lysate from HEK293-ACE2 cells ("ACE2").)
Transmembrane Protease, Serine 2 (TMPRSS-2), Cell Line (Cat# AAA434319)
Full Name
Human Transmembrane Protease, Serine 2 (TMPRSS-2) Stable Cell Line
MSX-130, Inhibitor (Cat# AAA579938)
Full Name
MSX-130
Purity
99.8%
Pricing
$240/1 mg | $285/2 mg | $330/5 mg | $390/10 mg | $605/25 mg | $785/50 mg | $3,265/5x50 mg
Isosilybin, Inhibitor (Cat# AAA579773)
Full Name
Isosilybin
Purity
100%
Pricing
$185/1 mg | $200/2 mg | $215/5 mg | $245/10 mg | $355/25 mg | $540/50 mg | $855/100 mg | $225/1 mL (in DMSO) | $3,580/5x100 mg
ADRA2A / Alpha-2A Adrenergic Receptor, Recombinant Protein (Cat# AAA2902625)
Full Name
Human ADRA2A / Alpha-2A Adrenergic Receptor Recombinant Protein
Gene Names
ADRA2A; ADRA2; ADRAR; ZNF32; ADRA2R; ALPHA2AAR
Applications
EIA, WB, AP
Purity
>95% by SDS-PAGE
Testing Data
Phosphodiesterase 4C (PDE4C), Cell Line (Cat# AAA430350)
Full Name
Phosphodiesterase 4C (PDE4C) ACTOne Stable Cell (CHO cell)
Gene Names
PDE4C; DPDE1; PDE21
Chemical Structure
Integrin-Antagonists-27, Inhibitor (Cat# AAA131187)
Full Name
Integrin-Antagonists-27
Purity
98%
Pricing
$1,055/100 mg | $2,765/500 mg
Angiotensin-Converting Enzyme 2 (ACE2), Cell Line (Cat# AAA434289)
Full Name
Human Angiotensin-Converting Enzyme 2 (ACE2) Stable Cell Line
Pricing
$5,270/1 Each
Structure
Calcium-Sensing Receptor Antagonists I, Inhibitor (Cat# AAA5752851)
Full Name
Calcium-Sensing Receptor Antagonists I
Purity
98.00%
Pricing
$340/10 mg | $925/100 mg | $360/1mL*10mM (in DMSO) | $3,875/5x100 mg
Structure
Integrin Antagonists 27, Inhibitor (Cat# AAA5755002)
Full Name
Integrin Antagonists 27
Purity
98.00%
Pricing
$335/2 mg | $425/5 mg | $560/10 mg | $1,400/50 mg | $1,910/100 mg | $420/1mL*10mM (in DMSO) | $8,300/5x100 mg
Testing Data
Sphingosine-1-Phosphate Receptor 5 (S1PR5), Cell Line (Cat# AAA430593)
Full Name
Sphingosine-1-Phosphate Receptor 5 (S1PR5) ACTOne Stable Cell Line, HEK293
Gene Names
S1PR5; EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
Testing Data
Sphingosine-1-Phosphate Receptor 3 (S1PR3), Cell Line (Cat# AAA430592)
Full Name
Sphingosine-1-Phosphate Receptor 3 (S1PR3) ACTOne Stable Cell Line, HEK293
Gene Names
S1PR3; EDG3; LPB3; S1P3; EDG-3
Sodium gualenate, Biochemical (Cat# AAA3610586)
Full Name
Sodium gualenate
Purity
>98% (HPLC)
Pricing
$190/5 mg | $570/5x5 mg
PF-06291874, Antagonist (Cat# AAA3845077)
Full Name
PF-06291874
Purity
>98%
Pricing
$240/1 mg | $615/5 mg | $1,005/10 mg | $2,900/50 mg
