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Angiotensin-Converting Enzyme 2 (ACE2) Cell Line | ACE2 cell line

Human Angiotensin-Converting Enzyme 2 (hACE2) Stable Cell Line

Synonyms
Angiotensin-Converting Enzyme 2 (ACE2); Human Angiotensin-Converting Enzyme 2 (hACE2) Stable Cell Line; ACE2 cell line
Ordering
For Research Use Only!
Host
HEK-293 Cells
Form/Format
Stable hACE2 cells: 1 mL (2 x 106 cells/mL in DMEM, 10% FBS, 10% DMSO)
Application Notes
SARS-CoV-2 entry study; Cell based high-throughput screening of human ACE2 antagonists
Characterizations
High level expression; Culture medium: DMEM+10%FBS+1X P/S +500 ug/ml G418.
Functional Tests
This cell line has been tested positive for ACE2 specific response
Survival rate: more than 2 million/vial on the second day after thawing
Mycoplasma Contamination Test
This lot of cells have been tested and found to be free of mycoplasma contamination.
Growth Properties
Adherent
Cell Culture Medium
Growth medium: DMEM+10%FBS+1X P/S +500 ug/ml G418
Freezing medium: 10% DMSO, 90% complete cell culture medium
Dry Ice Shipment
Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
Shipping Note
Product available only in the USA.
Preparation and Storage
Remove the frozen cells from the dry ice packaging and immediately place the cells at a temperature below -130 degree C, preferably in liquid nitrogen vapor, until ready for use.
Related Product Information for ACE2 cell line
Introduction: ACE2 is known to serve as the entry point into cells for some coronaviruses, including HCoV-NL63, SARS-CoV, and SARS-CoV-2. Cells in the lungs, arteries, heart, kidney, and intestines, express high level of ACE2 on their membrane surface. ACE2 is a promising drug target for treating cardiovascular diseases and for preventing COVID-19.

Description: This HEK293-hACE2 stable cell line expresses a recombinant human ACE2 (Angiotensin-Converting Enzyme 2) with the Green Fluorescent Protein (GFP) fused to its C-terminus. The cells have GFP signals on the cell membrane. The expression of ACE2 on the cell membrane was also confirmed with FACS analysis.

Gene/Enzyme Introduced: 1) Human ACE2 (EC 3.4.17.23) Other name(s): ACE-2; ACE2; hACE2; angiotensin converting enzyme 2; angiotensin converting enzyme-2; Tmem27
2) GFP (Green Fluorescent Protein)

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Product Notes

The ACE2 (Catalog #AAA434276) is a Cell Line produced from HEK-293 Cells and is intended for research purposes only. The product is available for immediate purchase. SARS-CoV-2 entry study; Cell based high-throughput screening of human ACE2 antagonists. Researchers should empirically determine the suitability of the ACE2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Angiotensin-Converting Enzyme 2 (ACE2), Cell Line" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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