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10000 results for " Activity" - showing 2350-2400


Immunohistochemistry (IHC) (Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with RAD51 Mouse Monoclonal Antibody (RAD51/2701).)

RAD51, Monoclonal Antibody (Cat# AAA4380673)

Full Name
RAD51 (Prognostic and Response to Chemotherapy Marker)
Gene Names
RAD51; RECA; BRCC5; FANCR; MRMV2; HRAD51; RAD51A; HsRad51; HsT16930
Reactivity
Human. Others not known.
Applications
Formalin-Fixed
Purity
Purified Ab with BSA and Azide at 200ug/ml OR Purified Ab WITHOUT BSA and Azide at 1.0mg/ml
Pricing
$390/0.1 mg (With BSA & Azide at 0.2mg/mL) | $390/0.1 mg (Without BSA & Azide at 1mg/mL) | $215/0.02 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (With BSA & Azide at 0.2mg/mL) | $1,710/5x0.1 mg (Without BSA & Azide at 1mg/mL)
Testing Data (TD) (MBS9203594 staining CDKN1A in human colon tissue sections by Immunohistochemistry (IHC-P - paraformaldehyde-fixed, paraffin-embedded sections). Tissue was fixed with formaldehyde and blocked with 3% BSA for 0. 5 hour at room temperature; antigen retrieval was by heat mediation with a citrate buffer (pH6). Samples were incubated with primary antibody (1/25) for 1 hours at 37°C. A undiluted biotinylated goat polyvalent antibody was used as the secondary antibody)

CDKN1A, Polyclonal Antibody (Cat# AAA9203594)

Full Name
CDKN1A Antibody (C-term)
Gene Names
CDKN1A; P21; CIP1; SDI1; WAF1; CAP20; CDKN1; MDA-6; p21CIP1
Reactivity
Human, mouse
Applications
IHC-P , WB , IF , EIA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL

CD14 CHO, Active Protein (Cat# AAA143087)

Full Name
Recombinant Human CD14 CHO
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
$180/0.01 mg | $250/0.05 mg | $2,690/1 mg | $11,875/5x1 mg

Urokinase Plasminogen Activator Receptor Recombinant, Active Protein (Cat# AAA637885)

Full Name
Urokinase Plasminogen Activator Receptor Recombinant, Human (uPAR, CD87)
Applications
EL/EIA
Purity
Purified
> 95%, as determined by SDS-PAGE and visualized by silver stain. Endotoxin: < 1.0 EU per 1 ug of the cytokine as determined by the LAL method.
Pricing
$790/0.1 mg | $3,550/5x0.1 mg

Aldose Reductase, Active Protein (Cat# AAA143685)

Full Name
Recombinant Human Aldose Reductase
Gene Names
AKR1B1; AR; ADR; ALR2; ALDR1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
$180/0.01 mg | $250/0.05 mg | $1,925/1 mg | $8,435/5x1 mg
Immunohistochemistry (IHC) (MBS9607220 at 1/100 staining Human urothelial cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22 degree C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.)

CEACAM1, Polyclonal Antibody (Cat# AAA9607220)

Full Name
CEACAM1 Antibody
Gene Names
CEACAM1; BGP; BGP1; BGPI
Reactivity
Human, Mouse
Applications
WB, IHC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL

Trefoil Factor-1, Active Protein (Cat# AAA143342)

Full Name
Recombinant Human Trefoil Factor-1
Gene Names
TFF1; pS2; BCEI; HPS2; HP1.A; pNR-2; D21S21
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$250/0.02 mg | $2,830/1 mg | $180/0.005 mg | $12,520/5x1 mg

Apo Transferrin (ATF), Active Protein (Cat# AAA555416)

Full Name
Human Apo Transferrin (ATF)
Reactivity
Human
Purity
Greater than 98.0% as determined by Cellulose Acetate Electrophoresis.
Pricing
$565/500 mg | $750/1 g | $3,215/5x1 g
Western Blot (WB) (Western blot analysis of CKIP-1 Antibody (N-term) in 293 cell line lysates (35ug/lane). CKIP-1 (arrow) was detected using the purified Pab.)

CKIP-1, Polyclonal Antibody (Cat# AAA9207531)

Full Name
CKIP-1 Antibody (N-term)
Gene Names
PLEKHO1; JBP; CKIP1; OC120; CKIP-1
Reactivity
Human (Predicted Reactivity: Bovine)
Applications
WB, EIA, IHC-P, FC/FACS
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL
Western Blot (WB) (Anti-CLN3 Antibody (Center) at 1:1000 dilution + Neuro-2a whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 48 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

CLN3, Polyclonal Antibody (Cat# AAA9211565)

Full Name
CLN3 Antibody (Center)
Gene Names
CLN3; BTS; JNCL
Reactivity
Human, mouse (Predicted Reactivity: Monkey)
Applications
FC/FACS, EIA, WB, IHC
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Pricing
$405/0.4 mL | $185/0.08 mL | $1,585/5x0.4 mL

RELM gamma, Active Protein (Cat# AAA692159)

Full Name
Mouse RELM gamma
Reactivity
Mouse
Purity
> 98% by SDS-PAGE gel and HPLC analyses
Pricing
$395/0.025 mg | $250/0.005 mg | $1,565/5x0.025 mg

PF-4 (CXCL4), Active Protein (Cat# AAA692010)

Full Name
Human PF-4 (CXCL4)
Gene Names
PF4; PF-4; CXCL4; SCYB4
Reactivity
Human
Purity
98 % (SDS-PAGE, HPLC)
Pricing
$395/0.02 mg | $250/0.005 mg | $1,565/5x0.02 mg

Growth Hormone, Chicken, Active Protein (Cat# AAA635876)

Full Name
Growth Hormone, Recombinant, Chicken (Somatotropin, GH)
Gene Names
GH; GH1
Purity
Highly Purified
~99% (SDS-PAGE, HPLC)
Pricing
$385/0.05 mg | $885/0.5 mg | $3,980/5x0.5 mg

HIV-1 env gp120, Strain ADA, Active Protein (Cat# AAA637212)

Full Name
HIV-1 env gp120, Strain ADA (M Tropic), Recombinant (Human Immunodeficiency Virus-1)
Purity
Affinity Purified
Purified by immunoaffinity chromatography. (95% by SDS-PAGE)
Pricing
$1,170/0.1 mg | $5,250/5x0.1 mg

MDC (CCL22), Active Protein (Cat# AAA692094)

Full Name
Mouse MDC (CCL22)
Gene Names
Ccl22; MDC; DCBCK; ABCD-1; Scya22
Reactivity
Mouse
Purity
> 98% (SDS-PAGE; HPLC)
Pricing
$395/0.02 mg | $250/0.005 mg | $1,565/5x0.02 mg
Activity Data (Calpain 1, Large Subunit (CAPN1) is an intracellular protease that requires calcium for its catalytic activity. Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. It has broad endopeptidase specificity. Besides, Signal Transducer And Activator Of Transcription 3 (STAT3) has been identified as an interactor of CAPN1, thus a binding ELISA assay was conducted to detect the interaction of recombinant rat CAPN1 and recombinant rat STAT3. Briefly, CAPN1 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to STAT3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-CAPN1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of CAPN1 and STAT3 was shown in Figure 1, and this effect was in a dose dependent manner.)

Calpain 1, Large Subunit (CAPN1), Active Protein (Cat# AAA2097302)

Full Name
Active Calpain 1, Large Subunit (CAPN1)
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$220/0.01 mg | $465/0.05 mg | $710/0.1 mg | $880/0.2 mg | $1,715/0.5 mg | $2,555/1 mg | $6,250/5 mg
Activity Data (Figure. The binding activity of TGFb3 with TGFbR2.Transforming growth factor beta-3 (TGFb3) is a type of protein, known as a cytokine, which is involved in cell differentiation, embryogenesis and development. It belongs to a large family of cytokines called the Transforming growth factor beta superfamily. TGFb3 is believed to regulate molecules involved in cellular adhesion and extracellular matrix (ECM) formation during the process of palate development. It also plays an essential role in controlling the development of lungs in mammals, by also regulating cell adhesion and ECM formation in this tissue, and controls wound healing by regulating the movements of epidermal and dermal cells in injured skin. Besides, Transforming Growth Factor Beta Receptor II (TGFbR2) has been identified as an interactor of TGFb3, thus a binding ELISA assay was conducted to detect the interaction of recombinant human TGFb3 and recombinant human TGFbR2. Briefly, TGFb3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to TGFbR2-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-TGFb3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TGFb3 and TGFbR2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Transforming Growth Factor Beta 3 (TGFb3), Active Protein (Cat# AAA2105156)

Full Name
Active Transforming Growth Factor Beta 3 (TGFb3)
Gene Names
TGFB3; ARVD; LDS5; RNHF; ARVD1; TGF-beta3
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$250/0.01 mg | $540/0.05 mg | $840/0.1 mg | $1,045/0.2 mg | $2,040/0.5 mg | $3,020/1 mg | $7,385/5 mg
Activity Data (TNFRSF14 (Tumor necrosis factor receptor superfamily member 14) belongs to the tumor necrosis factor receptor superfamily. TNFRSF14 functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. A binding ELISA assay was conducted to detect the association of TNFRSF14 with TNFa. Briefly, TNFRSF14 were diluted serially in PBS, with 0.01%BSA (pH 7.4). Duplicate samples of 100uL TNFRSF14 were then transferred to TNFa-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-TNFRSF14 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TNFRSF14 and TNFa was shown in Figure 1, and this effect was in a dose dependent manner.)

Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14), Active Protein (Cat# AAA2097313)

Full Name
Active Tumor Necrosis Factor Receptor Superfamily, Member 14 (TNFRSF14)
Gene Names
TNFRSF14; TR2; ATAR; HVEA; HVEM; CD270; LIGHTR
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$255/0.01 mg | $565/0.05 mg | $875/0.1 mg | $1,080/0.2 mg | $2,120/0.5 mg | $3,145/1 mg | $7,695/5 mg
Activity Data (IL1R1 (Interleukin 1 Receptor Type I), also known as CD121a, is an important mediator involved in many cytokine induced immune and inflammatory responses. It belongs to the interleukin-1 receptor family, and is a receptor for interleukin 1 alpha (IL1A), interleukin 1 beta (IL1B), and interleukin 1 receptor antagonist (IL1RA). Besides, mouse IL1B shares 87.0% AA sequence identity with rat IL1B, suggesting the exist of cross-species activity. Thus, a binding ELISA assay was constructed to detect the association of recombinant rat IL1R1 with recombinant mouse IL1B. Briefly, IL1R1 were diluted serially in PBS with 0.1%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to IL1B-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-IL1R1 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of IL1R1 with IL1B was shown in Figure 1 and this effect was in a dose dependent manner.)

Interleukin 1 Receptor Type I (IL1R1), Active Protein (Cat# AAA2097340)

Full Name
Active Interleukin 1 Receptor Type I (IL1R1)
Reactivity
Rat
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$160/0.01 mg | $300/0.05 mg | $460/0.1 mg | $565/0.2 mg | $1,080/0.5 mg | $1,600/1 mg | $3,920/5 mg

Thymosin-beta4, Active Protein (Cat# AAA691788)

Full Name
Human Thymosin-beta4
Gene Names
TMSB4X; FX; TB4X; PTMB4; TMSB4
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing
$250/0.02 mg | $395/0.1 mg | $1,565/5x0.1 mg
Activity Data (Leptin is a hormone made by adipose cells that helps to regulate energy balance by inhibiting hunger. Many of leptin's effects are mediated through neuropeptide- containing neurons and neuropeptide receptors in the hypothalamus. Although regulation of fat stores is deemed to be the primary function of leptin, it also plays a role in other physiological processes, as evidenced by its multiple sites of synthesis other than fat cells, and the multiple cell types beside hypothalamic cells that have leptin receptors. Besides, Hexokinase 3, White Cell (HK3) has been identified as an interactor of LEP, thus a binding ELISA assay was conducted to detect the interaction of recombinant human LEP and recombinant human HK3. Briefly, LEP were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to HK3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-LEPpAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of LEP and HK3 was shown in Figure 1, and this effect was in a dose dependent manner.)

Leptin (LEP), Active Protein (Cat# AAA2097261)

Full Name
Active Leptin (LEP)
Gene Names
LEP; OB; OBS; LEPD
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 90%
Pricing
$130/0.01 mg | $225/0.05 mg | $315/0.1 mg | $390/0.2 mg | $735/0.5 mg | $1,080/1 mg | $2,625/5 mg | $11,805/5x5 mg

Creatine Kinase Muscle Type-3, Active Protein (Cat# AAA142068)

Full Name
Recombinant Human Creatine Kinase Muscle Type-3
Gene Names
CKM; CKMM; M-CK
Purity
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$180/0.01 mg | $250/0.05 mg | $1,060/1 mg | $4,550/5x1 mg

CD28-Fc, Active Protein (Cat# AAA692481)

Full Name
Human CD28-Fc
Gene Names
CD28; Tp44
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analysis
Pricing
$250/0.02 mg | $395/0.1 mg | $1,565/5x0.1 mg

Phosphoinositide 3-kinase p110g, Active Protein (Cat# AAA142823)

Full Name
Recombinant Human Phosphoinositide 3-kinase p110g
Gene Names
PIK3C2B; C2-PI3K
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
$250/0.01 mg | $5,300/1 mg | $180/0.002 mg | $23,620/5x1 mg

Acid Phosphatase-5, Active Protein (Cat# AAA140634)

Full Name
Recombinant Human Acid Phosphatase-5
Gene Names
ACP5; HPAP; TRAP; TRACP5a; TRACP5b; TrATPase
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
$250/0.01 mg | $5,300/1 mg | $180/0.002 mg | $23,620/5x1 mg

Acid Phosphatase-6, Active Protein (Cat# AAA140877)

Full Name
Recombinant Human Acid Phosphatase-6
Gene Names
ACP6; LPAP; ACPL1; PACPL1
Purity
Greater than 95.0% as determined by SDS-PAGE.
Pricing
$250/0.02 mg | $2,830/1 mg | $180/0.005 mg | $12,520/5x1 mg

Interleukin-10, Active Protein (Cat# AAA142373)

Full Name
Recombinant Mouse Interleukin-10
Gene Names
Il10; CSIF; Il-10
Purity
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$250/0.01 mg | $4,845/1 mg | $180/0.002 mg | $21,590/5x1 mg

CXCL16, Active Protein (Cat# AAA143737)

Full Name
Recombinant Mouse CXCL16
Gene Names
Cxcl16; SR-PSOX; Zmynd15; AV290116; BB024863; CXCL16v1; CXCL16v2; b2b498Clo; 0910001K24Rik
Purity
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$2,830/1 mg | $250/0.025 mg | $180/0.005 mg | $12,520/5x1 mg

interferon alpha 2B, Active Protein (Cat# AAA400089)

Full Name
Human interferon alpha 2B
Purity
Greater than 98.0% as determined by:
(a) Analysis by RP-HPLC.
(b) Analysis by SDS-PAGE.
Pricing
$160/0.01 mg | $210/0.05 mg | $560/0.1 mg | $840/1 mg | $3,570/5x1 mg

PAF-AH, Active Protein (Cat# AAA691937)

Full Name
Human PAF-AH
Gene Names
PAFAH1B2; HEL-S-303
Reactivity
Human
Purity
> 95% by SDS-PAGE & HPLC analyses
Pricing
$395/0.02 mg | $250/0.005 mg | $1,565/5x0.02 mg

Phosphatase 1G, Active Protein (Cat# AAA145188)

Full Name
Recombinant Human Protein Phosphatase 1G 546 a.a.
Gene Names
PPM1G; PP2CG; PPP2CG; PP2CGAMMA
Purity
Greater than 85% as determined by SDS-PAGE.
Pricing
$250/0.01 mg | $5,300/1 mg | $180/0.002 mg | $23,620/5x1 mg

Leptin, Active Protein (Cat# AAA142381)

Full Name
Recombinant Chicken Leptin
Purity
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
Pricing
$180/0.02 mg | $250/0.1 mg | $1,315/1 mg | $5,695/5x1 mg

Leptin B, Active Protein (Cat# AAA400135)

Full Name
Tilapia (Oreochromis niloticus) leptin B
Purity
The purity of recombinant tilapia leptins is greater than 95.0% as determined by: (a) Gel filtration analysis. (b) Analysis by reducing and non-reducing SDS-PAGE gel.
Pricing
$235/0.1 mg | $650/0.5 mg | $1,115/1 mg | $3,820/5 mg | $5,650/10 mg | $13,700/100 mg

Fibronectin (FN1), Active Protein (Cat# AAA7115172)

Full Name
Recombinant Human Fibronectin (FN1), Partial
Gene Names
FN1; FN; CIG; FNZ; MSF; ED-B; FINC; GFND; LETS; GFND2; SMDCF
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$135/0.01 mg | $205/0.05 mg | $825/5x0.05 mg
Western Blot (WB) (Western blot analysis of B4GALT6 using HeLa whole cell lysates)

B4GALT6, Polyclonal Antibody (Cat# AAA9609592)

Full Name
B4GALT6 Antibody
Gene Names
B4GALT6; B4Gal-T6; beta4Gal-T6
Reactivity
Human, Mouse, Rat
Applications
WB, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from HT-29 cells using AHSA1 antibody.)

AHSA1, Polyclonal Antibody (Cat# AAA9604970)

Full Name
AHSA1 Antibody
Gene Names
AHSA1; p38; AHA1; hAha1; C14orf3
Reactivity
Human
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis of extracts from HuvEc cells, using MIA2 antibody., The lane on the left is treated with the antigen-specific peptide.)

MIA2, Polyclonal Antibody (Cat# AAA9605611)

Full Name
MIA2 Antibody
Gene Names
MIA2; MEA6; MGEA; TALI; MGEA6; CTAGE5; MGEA11
Reactivity
Human
Applications
WB, IF, ICC, EIA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL
Western Blot (WB) (Western blot analysis of eNOS phosphorylation expression in HepG2 whole cell lysates, The lane on the left is treated with the antigen-specific peptide.)

eNOS, Polyclonal Antibody (Cat# AAA9601019)

Full Name
Phospho-eNOS (Thr494) Antibody
Gene Names
NOS3; eNOS; ECNOS
Reactivity
Human, Mouse, Rat
Applications
WB, IF, ICC, EIA
Purity
From purified rabbit serum by affinity purification via sequential chromatography on phospho-and non-phospho-peptide affinity columns.
Pricing
$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL

LEPR, Active Protein (Cat# AAA636524)

Full Name
LEPR, Recombinant, Human (Leptin Receptor, LEP-R, HuB219, OB Receptor, OB-R, CD295, DB, OBR)
Purity
Highly Purified
~98% (SDS-PAGE, HPLC)
Pricing
$485/0.01 mg | $2,170/5x0.01 mg

Interleukin-17 A/F, Active Protein (Cat# AAA143518)

Full Name
Recombinant Rat Interleukin-17 A/F Heterodimer
Gene Names
IL17A; IL17; CTLA8; IL-17; IL-17A
Purity
Greater than 98.0% as determined by HPLC and SDS-PAGE.
Pricing
$250/0.01 mg | $1,015/0.1 mg | $180/0.002 mg | $4,355/5x0.1 mg

Apolipoprotein E3, Active Protein (Cat# AAA140648)

Full Name
Recombinant Human Apolipoprotein E3
Gene Names
APOE; AD2; LPG; APO-E; LDLCQ5
Purity
Greater than 95% as determined by SDS-PAGE.
Pricing
$180/0.1 mg | $330/0.5 mg | $540/1 mg | $2,200/5x1 mg

Carboxypeptidase-B, Active Protein (Cat# AAA691474)

Full Name
Rat Carboxypeptidase-B
Gene Names
Cpb1; Cpb
Purity
>95% by SDS-PAGE & HPLC analysis
Pricing
$395/0.025 mg | $250/0.005 mg | $1,565/5x0.025 mg
SDS-Page

Interleukin-4, Active Protein (Cat# AAA203304)

Full Name
Interleukin- 4, 25-153aa, Human, His tag, E Coli (Bioactivity Validated)
Gene Names
IL4; BSF1; IL-4; BCGF1; BSF-1; BCGF-1
Applications
SDS-PAGE
Purity
> 95% by SDS-PAGE
Pricing
$275/0.01 mg | $550/0.05 mg | $1,410/0.25 mg | $6,110/5x0.25 mg

Endostatin, Active, Active Protein (Cat# AAA637572)

Full Name
Endostatin, Active, Recombinant, Mouse
Purity
Purified
~95% (SDS-PAGE)
Pricing
$1,125/0.25 mg | $5,055/5x0.25 mg
Activity Data (NEU (Sialidase-1) is an enzyme that catalyzes the removal of sialic acid (N-acetylneuraminic acid) moities from glycoproteins and glycolipids. In the lysosome, this enzyme is part of a heterotrimeric complex together with beta-galactosidase and cathepsin A (CTSA). Thus a binding ELISA assay was conducted to detect the interaction of recombinant human NEU and recombinant human CTSA. Briefly, NEU were diluted serially in PBS, with 0.01%BSA (pH 7.4). Duplicate samples of 100uL were then transferred to CTSA-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-NEU pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of NEU and CTSA was shown in Figure 1, and this effect was in a dose dependent manner.)

Neuraminidase (NEU), Active Protein (Cat# AAA2097247)

Full Name
Active Neuraminidase (NEU)
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$230/0.01 mg | $505/0.05 mg | $780/0.1 mg | $970/0.2 mg | $1,890/0.5 mg | $2,800/1 mg | $6,840/5 mg
Activity Data (Interleukin-6 (IL-6), a pro-inflammatory cytokine and an anti-inflammatory myokine, plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It has been reported that IL-6 significantly increased the MMP-10 protein lever in the human lung cancer A549 cells through the JAK/STAT signaling pathway. Briefly, A549 cells were seeded into 6-well cell culture clusters and allowed to grow to 50-70% confluence, then different concentrations of IL-6 was added. After incubated for 24h, the protein levels of MMP-10 in the cell supernatant were determined by Western blot.MMP-10 protein lever significantly increased in A549 cells due to the stimulation of IL-6, the data was shown in Figure 1.)

Interleukin 6 (IL6), Active Protein (Cat# AAA2097327)

Full Name
Active Interleukin 6 (IL6)
Gene Names
IL6; IL-6; CHIL-6; interleukin-6
Reactivity
Human
Applications
Cell culture, Activity Assays
Purity
> 95%
Pricing
$165/0.01 mg | $310/0.05 mg | $480/0.1 mg | $585/0.2 mg | $1,120/0.5 mg | $1,660/1 mg | $4,075/5 mg
Activity Data (Matrix Metalloproteinase 13 (MMP13) is a member of the matrix metalloproteinase (MMP) family. MMP13 has been proposed to participate in aggrecan degradation associated with osteoarthritis and cleavage of type II collagen in osteoarthritic cartilage explants and in tumor progression and metastasis. MMP13 is likely to play a crucial role in the modulation of extracellular matrix degradation and cell-matrix interactions. In addition, it can cleave type I, III, IV, IX, X and XIV collagens and fibronectin. Thus we have chosed casein-zymography to measure the activity of MMP13. Briefly, various concentrations of MMP13 (10ug, 5ug, 1ug, 0.1ug, 0.01ug) were denatured by SDS loading buffer, electrophoresed through sodium dodecylsulphat-polyacrylamide gel (SDS-PAGE; 15% gels) containing casein (1 mg/mL) with nonreducing conditions. After renaturation, incubation and CCB-stained, active MMP13 would hydrolyze casein nearby, which was indicated by the white bands on the gel. In this experiment we use heat-denatured MMP13 protein as negative control, and trypsase (1ug/mL) as positive control.Result : Casein hydrolysis by recombinant human MMP13 was shown in figure 1.)

Matrix Metalloproteinase 13 (MMP13), Active Protein (Cat# AAA2105075)

Full Name
Active Matrix Metalloproteinase 13 (MMP13)
Gene Names
MMP13; CLG3; MDST; MANDP1; MMP-13
Applications
Cell Culture, Activity Assays
Purity
> 95%
Pricing
$235/0.01 mg | $510/0.05 mg | $790/0.1 mg | $980/0.2 mg | $1,915/0.5 mg | $2,830/1 mg | $6,925/5 mg
Activity Data (Figure. The binding activity of TIMP3 with MMP2.Tissue Inhibitors Of Metalloproteinase 3 (TIMP3) is an protein belongs to the tissue inhibitor of metalloproteinases family. They are inhibitors of the matrix metalloproteinases. TIMP-3 is the only member of the TIMP family which is found exclusively in the extracellular matrix (ECM). It is regulated in a cell cycle-dependent fashion in certain cell types and may serve as a marker for terminal differentiation. Besides, Matrix Metalloproteinase 2 (MMP2) has been identified as an interactor of TIMP3, thus a binding ELISA assay was conducted to detect the interaction of recombinant rat TIMP3 and recombinant rat MMP2. Briefly, TIMP3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to MMP2-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-TIMP3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of TIMP3 and MMP2 was shown in Figure 1, and this effect was in a dose dependent manner.)

Tissue Inhibitors Of Metalloproteinase 3 (TIMP3), Active Protein (Cat# AAA2105081)

Full Name
Active Tissue Inhibitors Of Metalloproteinase 3 (TIMP3)
Gene Names
Timp3; Timp-3
Applications
Cell Culture, Activity Assays
Purity
> 97%
Pricing
$220/0.01 mg | $460/0.05 mg | $705/0.1 mg | $875/0.2 mg | $1,705/0.5 mg | $2,540/1 mg | $6,205/5 mg
Activity Data (Puromycin Sensitive Aminopeptidase (PSA) also known as cytosol alanyl aminopeptidase or alanine aminopeptidase (AAP) is used as a biomarker to detect damage to the kidneys, and that may be used to help certain kidney disorders. It is found at high levels in the urine when there are kidney problems. PSA has been proposed to function in a variety of processes, including metabolism of neuropeptidase, regulation of the cell cycle, and hydrolysis of proteasomal products to amino acids. Besides, Protein Disulfide Isomerase A3 (PDIA3) has been identified as an interactor of PSA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PSA and recombinant human PDIA3. Briefly, PSA were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to PDIA3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PSA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PSA and PDIA3 was shown in Figure 1, and this effect was in a dose dependent manner.Figure. The binding activity of PSA with PDIA3)

Puromycin Sensitive Aminopeptidase (PSA), Active Protein (Cat# AAA2105185)

Full Name
Active Puromycin Sensitive Aminopeptidase (PSA)
Gene Names
NPEPPS; PSA; AAP-S; MP100
Applications
Cell Culture, Activity Assays
Purity
> 90%
Pricing
$165/0.01 mg | $315/0.05 mg | $485/0.1 mg | $600/0.2 mg | $1,145/0.5 mg | $1,705/1 mg | $4,180/5 mg
Activity Data (Figure. The binding activity of PAPPA with Plg.Pregnancy-associated plasma protein A (PAPPA), also known as pappalysin-1, is a secreted protease whose main substrate is insulin-like growth factor binding proteins. PAPPA's proteolytic function is activated upon collagen binding. It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses (fetuses with an abnormal number of chromosomes). Besides, Plasminogen (Plg) has been identified as an interactor of PAPPA, thus a binding ELISA assay was conducted to detect the interaction of recombinant human PAPPA and recombinant human Plg. Briefly, PAPPA were diluted serially in PBS with 0.01% BSA (pH 7.4). Duplicate samples of 100muL were then transferred to Plg-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-PAPPA pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of PAPPA and Plg was shown in Figure 1, and this effect was in a dose dependent manner.)

Pregnancy Associated Plasma Protein A (PAPPA), Active Protein (Cat# AAA2105118)

Full Name
Active Pregnancy Associated Plasma Protein A (PAPPA)
Gene Names
PAPPA; PAPA; DIPLA1; PAPP-A; PAPPA1; ASBABP2; IGFBP-4ase
Applications
Cell Culture, Activity Assays
Purity
> 97%
Pricing
$215/0.01 mg | $445/0.05 mg | $685/0.1 mg | $845/0.2 mg | $1,645/0.5 mg | $2,450/1 mg | $5,990/5 mg
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