Western Blot (WB)
(Western Blot analysis of extracts from rat lung tissue, using BTG2 Antibody. The lane on the left was treated with bolcking peptides.)
Rabbit anti-Human, Rat BTG2 Polyclonal Antibody | anti-BTG2 antibody
BTG2 Antibody
Gene Names
BTG2; PC3; APRO1; TIS21
Reactivity
Human, Rat
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
BTG2; Polyclonal Antibody; BTG2 Antibody; B cell translocation gene 2; BTG family member 2; Btg2; BTG2_HUMAN; Nerve growth factor inducible anti proliferative; NGF inducible anti proliferative protein PC3; NGF-inducible anti-proliferative protein PC3; PC3; Pheochromacytoma cell 3; Protein BTG2; TIS21; anti-BTG2 antibody
Host
Rabbit
Reactivity
Human, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
BTG2 Antibody detects endogenous levels of total BTG2.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-BTG2 antibody
Western Blot (WB), ELISA (EIA)(peptide)
Application Notes
WB: 1:500-1:2000
ELISA(peptide): 1:20000-1:40000
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Similarity
Belongs to the BTG family.
Post Translational Modifications
Phosphorylated at Ser-147 by MAPK1/ERK2 and MAPK3/ERK1, and at Ser-149 by MAPK14, leading to PIN1-binding and mitochondrial depolarization.
Subunit Structure
Interacts with PRKCABP (By similarity). Interacts with CNOT7 and CNOT8; indicative for an association with the CCR4-NOT complex. Interacts with PIN1, inducing mitochondrial depolarization.
Function
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western Blot analysis of extracts from rat lung tissue, using BTG2 Antibody. The lane on the left was treated with bolcking peptides.)
Western Blot (WB)
(Western Blot analysis of extracts from rat lung tissue, using BTG2 Antibody. The lane on the left was treated with bolcking peptides.)
Product Categories/Family for anti-BTG2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
17,416 Da
NCBI Official Full Name
protein BTG2
NCBI Official Synonym Full Names
BTG anti-proliferation factor 2
NCBI Official Symbol
BTG2
NCBI Official Synonym Symbols
PC3; APRO1; TIS21
NCBI Protein Information
protein BTG2
UniProt Protein Name
Protein BTG2
Protein Family
UniProt Gene Name
BTG2
UniProt Synonym Gene Names
PC3
NCBI Description
The protein encoded by this gene is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties. This encoded protein is involved in the regulation of the G1/S transition of the cell cycle. [provided by RefSeq, Jul 2008]
Uniprot Description
Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth.
Research Articles on BTG2
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Product Notes
The BTG2 btg2 (Catalog #AAA9629395) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BTG2 Antibody reacts with Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's BTG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA)(peptide). WB: 1:500-1:2000 ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the BTG2 btg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "BTG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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