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Testing Data

General Hydroxyurea Colorimetric Assay Kit

Hydroxyurea Colorimetric Assay Kit

Reactivity
General
Synonyms
Hydroxyurea Colorimetric; Hydroxyurea Colorimetric Assay Kit; Hydroxyurea Colorimetric assay kit
Ordering
For Research Use Only!
Reactivity
General
Specificity
Determination of HU in biological samples. It can detect as low as 2nMole of HU under the assay conditions.
Detection Method
Absorbance 540nM
Sample Type
Serum or plasma
Features & Benefits
It's the first, commerically available kit to measure HU concentrations in human serum or plasma. Simple, rapid. Sensitive and convenient way to measure HU concentrations in samples
Preparation and Storage
Store at -20 degree C
Shipping: Gel Pack
Shelf Life: Est.~12 months

Testing Data

Testing Data
Related Product Information for Hydroxyurea Colorimetric assay kit
Hydroxyurea (HU), also known as carbamohydroxamic acid is a small molecule drug and is used in a number of myeloproliferative, neoplastic, and non-hematological diseases. HU can promote hemoglobin synthesis, reduce thrombocytosis and is an anti-cancer agent for treating chronic myeloid leukemia, melanoma, head and neck cancer and refractory ovarian cancer. HU is also approved by FDA for treating Sickle Cell Disease. Additionally, HU is a ribonucleotide reductase inhibitor and blocks DNA replication and cell division. HU has some side effects including nausea, vomiting, diarrhea, sore throat, ulcers, fever, cough and shortness of breath. Thus, it is important to quantify HU concentration in serum or plasma. Hydroxyurea Colorimetric Assay Kit is the first, commerically available kit to measure HU concentrations in human serum or plasma. In this assay, HU is reduced by a series of redox reactions to form an intermediate, which in the presence of detection reagents generates a colored product measured at 540nM. The colored signal is directly proportional to the HU concentration in the sample. The kit offers a simple, rapid, sensitive and convenient way to measure HU concentrations in samples. It can detect as low as 2nMole of HU under the assay conditions.

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Product Notes

The General Hydroxyurea Colorimetric (Catalog #AAA8400628) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8400628 Assay Kit recognizes General Hydroxyurea Colorimetric. It is sometimes possible for the material contained within the vial of "Hydroxyurea Colorimetric, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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