Testing Data
General Alpha-Mannosidase Assay Kit
Alpha-Mannosidase Activity Assay Kit (Fluorometric)
Reactivity
General
Synonyms
Alpha-Mannosidase; Alpha-Mannosidase Activity Assay Kit (Fluorometric); Alpha-Mannosidase assay kit
Reactivity
General
Specificity
Measurement of alpha mannosidase activity in various samples. Can detect as low as 1.0 uU of alpha mannosidase activity. The substrate is specific to alpha-Man and can differentiate from beta-mannosidase.
Detection Method
Fluorescence (Ex/Em = 360/445nM)
Sample Type
Tissue homogenates: Rat liver, Cell Lysates: 3T3 cells, Biological fluids: Human plasma
Features & Benefits
A facile, rapid way to monitor total Alpha-Mannosidase in various biological samples. The substrate is specific to alpha-Man and can differentiate from beta-mannosidase.
Preparation and Storage
Store at -20 degree C
Shipping: Gel Pack
Shelf Life: Est.~12 months
Shipping: Gel Pack
Shelf Life: Est.~12 months
Testing Data
Testing Data
Related Product Information for Alpha-Mannosidase assay kit
Alpha-Mannosidase (alpha-Man; EC 3.2.1.24) is a glycoside hydrolase involved in the cleavage of the alpha-mannose. alpha-Man can be applied in studies that determine the effects of mannose on specific molecules, such as recombinant proteins that are used for vaccine development. Lysosomal alpha-Man is essential for catabolizing the Asn-linked glycans of glycoproteins and is actively involved in maintaining the cellular homeostasis. alpha-Man deficiency results in Alpha-Mannosidosis, an acquired lysosomal storage disorder in which alpha-Man fails to break down mannose-containing oligosaccharides. These oligosaccharides, therefore, accumulate in lysosomes thereby leading to cellular malfunction and apoptosis. Alpha-Mannosidase Activity Assay Kit provides a facile, rapid way to monitor total alpha-Man activity in various biological samples. In this kit, alpha-Man cleaves a synthetic specific substrate and releases a fluorophore, which can be easily quantified (Ex/Em = 360/445nM). The substrate is specific to alpha-Man and can differentiate from beta-mannosidase. The assay is simple, sensitive and can detect as low as 1.0 uU of alpha mannosidase activity.
Product Categories/Family for Alpha-Mannosidase assay kit
Similar Products
Product Notes
The General Alpha-Mannosidase (Catalog #AAA8400623) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8400623 Assay Kit recognizes General Alpha-Mannosidase. It is sometimes possible for the material contained within the vial of "Alpha-Mannosidase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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