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Typical Testing Data/Standard Curve (for reference only)

CETP Activity II Assay Kit

CETP Activity Fluorometric Assay Kit II

Synonyms
CETP Activity II; CETP Activity Fluorometric Assay Kit II; CETP Activity II assay kit
Ordering
For Research Use Only!
Application Notes
Measurement of CETP activity in animal serum, plasma and recombinant protein
Samples
Animal plasma (recommended) or serum, recombinant cetp protein
Preparation and Storage
4 degree C
Shelf Life: 12 months

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for CETP Activity II assay kit
Background/Introduction: Cholesteryl ester transfer protein (CETP) is a plasma protein that transfers a cholesteryl ester from HDL to LDL or VLDL in exchange for a triglyceride. HDL plays an important role in lipid metabolism and cardiovascular health. HDL transports cholesterol to the liver for excretion or to steroidogenic tissues for steroid synthesis. HDL also plays an important role in the reverse cholesterol transport pathway, removing cholesterol from lipid-filled macrophages, protecting against atherosclerosis. Because of this function, CETP is viewed as a target to increase HDL, with CETP inhibition an active area of research and several CETP inhibitors at various stages of drug development. CETP Activity Fluorometric Assay Kit uses a lipoprotein donor molecule containing a quenched fluorescent cholesteryl ester analogue that is unquenched upon transfer to an acceptor molecule. The fluorometric intensity is directly proportional to the amount of neutral lipid transfer. Rabbit serum is provided as a positive control and CETP inhibitor torcetrapib is included for assay validation. This Assay Kit, in addition to measuring activity in plasma/serum samples, is also suitable for testing activity of recombinant CETP proteins.

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Product Notes

The CETP Activity II (Catalog #AAA841829) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Measurement of CETP activity in animal serum, plasma and recombinant protein. Researchers should empirically determine the suitability of the CETP Activity II for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CETP Activity II, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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