Typical Testing Data/Standard Curve (for reference only)
HDL Uptake Assay Kit
HDL Uptake Assay Kit (Fluorometric)
Synonyms
HDL Uptake; HDL Uptake Assay Kit (Fluorometric); High-density lipoprotein Uptake Assay Kit (Fluorometric); HDL Uptake assay kit
Application Notes
Measure HDL uptake in different cell types
Screen, study or characterize stimulators or inhibitors of HDL uptake
Screen, study or characterize stimulators or inhibitors of HDL uptake
Samples
Cells
Detection Method
Fluorescence (Ex/Em 540/575 nm)
Features & Benefits
Only Kit on the market to quantitatively measure HDL uptake.
Includes unlabeled-HDL for assay validation.
Includes unlabeled-HDL for assay validation.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for HDL Uptake assay kit
Product Information: HDL Uptake Assay Kit (Fluorometric): Only kit on the market to measure HDL uptake in variety of cells. 100 assays
Background: High-density lipoprotein (HDL) consists of a protein shell, containing apolipoproteins A-I and A-II, and a hydrophobic core consisting of cholesterol and triglycerides surrounded by phospholipids and cholesterol esters. HDL transports cholesterol to the liver or steroidogenic organs such as adrenals, ovary, and testes by both direct and indirect pathways. HDL-Cholesterol is removed by HDL receptors such as scavenger receptor BI (SR-BI), which mediate the selective uptake of cholesterol from HDL. Clinically, high levels of HDL has been associated with cardiovascular health. This is due to the ability of HDL particle to transport cholesterol from lipid-laden macrophages of atherosclerotic arteries to the liver for secretion into the bile by a process called as reverse cholesterol transport. MyBioSource's HDL Uptake Assay Kit contains a fluorescently-labeled HDL that can be measured when taken up by cells. Unlabeled-HDL is included in the kit for assay validation.
Summary: Detection method- Fluorescence (Ex/Em 540/575 nm) Applications:
Measure HDL uptake in different cell types
Screen, study or characterize stimulators or inhibitors of HDL uptake
Background: High-density lipoprotein (HDL) consists of a protein shell, containing apolipoproteins A-I and A-II, and a hydrophobic core consisting of cholesterol and triglycerides surrounded by phospholipids and cholesterol esters. HDL transports cholesterol to the liver or steroidogenic organs such as adrenals, ovary, and testes by both direct and indirect pathways. HDL-Cholesterol is removed by HDL receptors such as scavenger receptor BI (SR-BI), which mediate the selective uptake of cholesterol from HDL. Clinically, high levels of HDL has been associated with cardiovascular health. This is due to the ability of HDL particle to transport cholesterol from lipid-laden macrophages of atherosclerotic arteries to the liver for secretion into the bile by a process called as reverse cholesterol transport. MyBioSource's HDL Uptake Assay Kit contains a fluorescently-labeled HDL that can be measured when taken up by cells. Unlabeled-HDL is included in the kit for assay validation.
Summary: Detection method- Fluorescence (Ex/Em 540/575 nm) Applications:
Measure HDL uptake in different cell types
Screen, study or characterize stimulators or inhibitors of HDL uptake
Product Categories/Family for HDL Uptake assay kit
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Product Notes
The HDL Uptake (Catalog #AAA841517) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Measure HDL uptake in different cell types Screen, study or characterize stimulators or inhibitors of HDL uptake. Researchers should empirically determine the suitability of the HDL Uptake for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HDL Uptake, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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