Neuropeptide Y Receptor Y5 Assay System | NPY5R assay system
Neuropeptide Y Receptor Y5 (NPY5R) ACTOneTM Stable Cell Line
Gene Names
NPY5R; NPYR5; NPY5-R; NPYY5-R
Synonyms
Neuropeptide Y Receptor Y5; Neuropeptide Y Receptor Y5 (NPY5R) ACTOneTM Stable Cell Line; Neuropeptide Y Receptor Y5 (NPY5R) ACTOne Stable Cell Line; NPY5R assay system
Sequence Length
445
Application Notes
cAMP dependent human NPY5R cell-based assay; cell-based high-throughput screening of human NPY5R agonists/antagonists
Note
To order this product, please inquire about a use license.
Preparation and Storage
Product is shipped on dry ice. Storage: Remove the frozen cells from the dry ice packaging and immediately place the cells at a temperature below -130 degrees C preferably in liquid nitrogen vapor, until ready for use.
Related Product Information for NPY5R assay system
This cell line is a HEK-293-CNG cell line that expresses a recombinant human NPY5R. HEK-293-CNG cells express a modified CNG (Cyclic Nucleotide Gated) channel that opens in response to elevated intracellular cAMP levels and consequently result in ion flux and cell membrane depolarization.
cAMP dependent human NPY5R cell-based assay; cell-based high-throughput screening of human NPY5R agonists/antagonists
cAMP dependent human NPY5R cell-based assay; cell-based high-throughput screening of human NPY5R agonists/antagonists
Product Categories/Family for NPY5R assay system
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
50,727 Da
NCBI Official Full Name
neuropeptide Y receptor Y5
NCBI Official Synonym Full Names
neuropeptide Y receptor Y5
NCBI Official Symbol
NPY5R
NCBI Official Synonym Symbols
NPYR5; NPY5-R; NPYY5-R
NCBI Protein Information
neuropeptide Y receptor type 5
UniProt Protein Name
Neuropeptide Y receptor type 5
Protein Family
UniProt Gene Name
NPY5R
UniProt Synonym Gene Names
NPYR5; NPY5-R; NPYY5-R; Y5 receptor
UniProt Entry Name
NPY5R_HUMAN
Uniprot Description
NPY5R: Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. Belongs to the G-protein coupled receptor 1 family.
Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 4q31-q32
Cellular Component: integral to plasma membrane; plasma membrane
Molecular Function: neuropeptide Y receptor activity
Biological Process: cell surface receptor linked signal transduction; feeding behavior; G-protein coupled receptor protein signaling pathway; synaptic transmission
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Product Notes
The NPY5R npy5r (Catalog #AAA430196) is an Assay System and is intended for research purposes only. The product is available for immediate purchase. cAMP dependent human NPY5R cell-based assay; cell-based high-throughput screening of human NPY5R agonists/antagonists. Researchers should empirically determine the suitability of the NPY5R npy5r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Neuropeptide Y Receptor Y5, Assay System" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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