PLAC9 recombinant protein

PLAC9 Protein, Human, Recombinant (mFc Tag)

Cat. Num. AAA8121600

• Purity: >90% as determined by SDS-PAGE
• Synonyms: PLAC9; PLAC9 Protein; Human; Recombinant (mFc Tag); Human PLAC9/Placenta-specific 9 Protein (Fc Tag); placenta specific 9; PLAC9 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >90% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Phe97

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Ala 23
• Tag: C-mouse IgG1-Fc
• Protein Construction: A DNA sequence encoding the huamn PLAC9 (Q5JTB6)(Met1-Phe97) was fused with Fc region of mouse IgG at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

Related Product Information for PLAC9 recombinant protein

Background: PLAC9 belongs to the PLAC9 family. PLAC9 gene is a placental-enriched gene. There are other two placental-enriched genes: Plac1 and Plac8. Plac1 is strongly expressed in all trophoblast-derived cells in the placenta and has been described in 2. Plac8 expression is restricted to the spongiotrophoblast layer during development, whereas PLAC9 is weakly expressed though highly enriched in placenta. For both, cDNAs with complete open reading frames were recovered and exon-intron structures inferred from comparisons of mouse cDNA and genomic sequence. The predicted proteins both contain putative signal peptides, with a coiled-coil segment of mPLAC9 as the only other detected motif. Genomic sequence comparisons reveal that in addition to an apparent pseudogene on chromosome 1, Plac8 is expressed at mouse cytoband 5e3.

References

Deloukas P. et al., 2004, Nature. 429 (6990): 375-81. Galaviz-Hernandez C. et al., 2003, Gene. 309 (2): 81-9. Gerhard DS. et al., 2004, Genome Res. 14 (10B): 2121-7.

NCBI and Uniprot Product Information

• NCBI GI #: 61175222
• NCBI GeneID: 219348
• NCBI Accession #: NP_001012991.1
• NCBI GenBank Nucleotide #: NM_001012973.1
• UniProt Accession #: Q5JTB6
• Molecular Weight: 10,309 Da
• NCBI Official Full Name: placenta-specific protein 9
• NCBI Official Synonym Full Names: placenta-specific 9
• NCBI Official Symbol: PLAC9
• NCBI Protein Information: placenta-specific protein 9
• UniProt Protein Name: Placenta-specific protein 9
• Protein Family: Placenta-specific protein
• UniProt Gene Name: PLAC9

Uniprot Description

PLAC9: Belongs to the PLAC9 family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q22.3

Cellular Component: extracellular region

Molecular Function: protein binding