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Testing Data

General Tissue Plasminogen Activator (tPA) Assay Kit

Tissue Plasminogen Activator (tPA) Activity Assay Kit (Colorimetric)

Reactivity
General
Synonyms
Tissue Plasminogen Activator (tPA); Tissue Plasminogen Activator (tPA) Activity Assay Kit (Colorimetric); tissue-type plasminogen activato; PLAT; tPA; Tissue Plasminogen Activator (tPA) assay kit
Ordering
For Research Use Only!
Reactivity
General
Samples
Biological Fluids: Plasma, Saliva, etc
Tissue Homogenates: Kidney
Detection Method
Colorimetric: OD: 405nm
Features & Benefits
Non-Radioactive
High throughput compatible
Rapid, easy, one-step assay
Rapid assessment of enzymatic activity of tPA in biological samples
Analysis and study of Fibrinolytic system
Measurement of tPA activity in various Biological Fluids, Tissues and Cell Culture Supernatants
The most sensitive assay to measure tPA activity in biological samples
Preparation and Storage
Store at -20 degree C
Shelf life: ~12 months

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Related Product Information for Tissue Plasminogen Activator (tPA) assay kit
Tissue plasminogen Activator (tPA, PLAT or tissue-type plasminogen activator; EC 3.4.21.68) is a serine protease that is found in blood & some tissues. tPA is the major intravascular activator of plasminogen. Thus, tPA is a key enzyme and the primary initiator of fibrinolysis in the vascular system where it plays an important role in the breakdown of blood clots. tPA has therapeutic uses and it is known as the "clot buster" in clinical settings. High tPA activity in blood leads to hyperfibrinolysis and causes excessive bleeding; while low tPA activity leads to hypofibrinolysis, a condition that increases patient's risks of suffering an arterial thrombosis. Tissue Plasminogen Activator (tPA) Activity Assay Kit utilizes the ability of active tPA to hydrolyze the synthetic substrate releasing pNA (chromophore). The released pNA can be easily quantified by OD: 405 nm. Our kit uses a unique combination of Substrate and Inhibitor Mix that specifically detects tPA in a variety of Biological Samples. Other enzymes with similar catalytic properties [i.e. uPA (urokinase or urokinase-type plasminogen activator) ] do not interfere with the assay. Our assay kit is simple, specific and can detect as low as 5 uU of tPA activity.

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Product Notes

The General Tissue Plasminogen Activator (tPA) (Catalog #AAA849567) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849567 Assay Kit recognizes General Tissue Plasminogen Activator (tPA). It is sometimes possible for the material contained within the vial of "Tissue Plasminogen Activator (tPA), Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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