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616 results for " Tyrosine Kinase Inhibitors" - showing 1-50
Testing Data
EGFR, Monoclonal Antibody (Cat# AAA670104)
Full Name
Mouse Anti-Human EGFR-UNLB
Gene Names
EGFR; ERBB; HER1; mENA; ERBB1; PIG61
Reactivity
Human
Applications
Immunohistochemistry; Western Blot
Pricing
$300/0.1 mg | $1,200/5x0.1 mg
Activity Data
(Suppressor of cytokine signaling 3 (SOCS3) is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family that negatively regulates cytokine signal transduction. SOCS3 is feedback inhibitors of the Janus kinase (JAK) and signal transducer and activator of transcription (STAT) signaling pathway. Inhibits cytokine signal transduction by binding to tyrosine kinase receptors including gp130, LIF, erythropoietin, insulin, IL12, GCSF and leptin receptors. SOCS3 also can bind to JAK2 kinase inhibits its kinase activity and nhibits insulin signaling in adipose tissue and the liver. Besides, Glycoprotein 130 (gp130) has been identified as an interactor of SOCS3, thus a binding ELISA assay was conducted to detect the interaction of recombinant mouse SOCS3 and recombinant mouse gp130. Briefly, SOCS3 were diluted serially in PBS, with 0.01% BSA (pH 7.4). Duplicate samples of 100uL were then transferred to SOCS3-coated microtiter wells and incubated for 2h at 37 degree C. Wells were washed with PBST and incubated for 1h with anti-SOCS3 pAb, then aspirated and washed 3 times. After incubation with HRP labelled secondary antibody, wells were aspirated and washed 3 times. With the addition of substrate solution, wells were incubated 15-25 minutes at 37 degree C. Finally, add 50uL stop solution to the wells and read at 450nm immediately. The binding activity of of SOCS3 and gp130 was shown in Figure 1, and this effect was in a dose dependent manner.)
Suppressors Of Cytokine Signaling 3 (SOCS3), Active Protein (Cat# AAA2097298)
Full Name
Active Suppressors Of Cytokine Signaling 3 (SOCS3)
Gene Names
Socs3; Cis3; Ef10; Ssi3; Cish3; EF-10; SSI-3
Reactivity
Mouse
Applications
Cell culture, Activity Assays
Purity
> 97%
Pricing
$215/0.01 mg | $450/0.05 mg | $690/0.1 mg | $850/0.2 mg | $1,660/0.5 mg | $2,470/1 mg | $6,035/5 mg
Western Blot
(Western Blot analysis using FAK antibodyWestern Blot showing FAK antibody used against FAK (AA: 354-533)-hIgGFc transfected HEK293 cell lysate.)
FAK, Monoclonal Antibody (Cat# AAA830319)
Full Name
FAK antibody
Applications
EIA, WB
Pricing
$480/0.1 mL | $2,150/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence staining of methanol-fixed Hela cells using syk (Phospho-Tyr323) antibody)
SYK, Polyclonal Antibody (Cat# AAA5309637)
Full Name
SYK antibody
Gene Names
Syk; Sykb
Applications
IF, IHC, WB
Purity
Purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
Western Blot
(Western Blot analysis using FLT4 antibodyWestern Blot showing FLT4 antibody used against FLT4 (AA: 25-330)-hIgGFc transfected HEK293 cell lysate.)
FLT4, Monoclonal Antibody (Cat# AAA831840)
Full Name
FLT4 antibody
Gene Names
FLT4; PCL; FLT41; LMPH1A; VEGFR3
Applications
EIA, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence analysis of B16 cells using FAK antibody (green). Blue: DRAQ5 fluorescent DNA dye.)
FAK, Monoclonal Antibody (Cat# AAA5310902)
Full Name
FAK antibody
Applications
EIA, IF, IHC, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence staining of methanol-fixed Hela cells using FAK antibody)
FAK, Polyclonal Antibody (Cat# AAA5309730)
Full Name
FAK antibody
Applications
IF, IHC, WB
Purity
Purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant PKMYT1 protein (Right) or empty vector (Left) detected with PKMYT1 antibody)
PKMYT1, Monoclonal Antibody (Cat# AAA832121)
Full Name
PKMYT1 antibody
Gene Names
PKMYT1; MYT1; PPP1R126
Applications
FC/FACS, IF, IHC, WB
Purity
PKMYT1 antibody was purified by affinity chromatography.
Pricing
$885/0.1 mL | $3,965/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence staining of methanol-fixed Hela cells using syk antibody)
SYK, Polyclonal Antibody (Cat# AAA5309848)
Full Name
SYK antibody
Gene Names
Syk; Sykb
Applications
IF, IHC, WB
Purity
Purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
Western Blot
(Western Blot analysis using EPHA5 antibodyWestern Blot showing EPHA5 antibody used against truncated EPHA5-His recombinant protein (1) and truncated EPHA5 (aa620-774)-hIgGFc transfected CHO-K1 cell lysate (2).)
EPHA5, Monoclonal Antibody (Cat# AAA831471)
Full Name
EPHA5 antibody
Gene Names
EPHA5; EK7; CEK7; EHK1; HEK7; EHK-1; TYRO4
Applications
EIA, WB
Pricing
$525/0.1 mL | $2,355/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence staining of methanol-fixed Hela cells using GSK3beta (Phospho-Tyr216) antibody)
GSK3 beta, Polyclonal Antibody (Cat# AAA5309611)
Full Name
GSK3 beta antibody
Gene Names
gsk3b.L; gsk3; gsk-3; gsk3b; xgsk-3; gsk3beta; gsk3-beta
Applications
IF, IHC, WB
Purity
Purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
Immunofluorescence (IF)
(Immunofluorescence staining of methanol-fixed Hela cells using MEK1/MEK2 antibody)
MEK1/MEK2, Polyclonal Antibody (Cat# AAA835679)
Full Name
MEK1/MEK2 antibody
Gene Names
Map2k2; MK2; MEK2; Prkmk2; AA589381
Applications
IF, IHC, WB
Purity
MEK1/MEK2 antibody was purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
Flow Cytometry (FC/FACS)
(FC analysis of HL-60 cells using CSK antibody (green) and negative control (purple).)
CSK, Monoclonal Antibody (Cat# AAA5310908)
Full Name
CSK antibody
Applications
EIA, IF, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Western Blot (WB)
(Western Blot showing STYK1 antibody used against truncated STYK1 recombinant protein (1) and STYK1 (aa47-422)-hIgGFc transfected CHO-K1 cell lysate (2).)
STYK1, Monoclonal Antibody (Cat# AAA831125)
Full Name
STYK1 antibody
Gene Names
Styk1; Nok; AI326477; 9130025L13
Applications
IHC, WB
Pricing
$645/0.1 mL | $2,885/5x0.1 mL
Ephrin Type-A Receptor 4 (EPHA4), Active Protein (Cat# AAA7115165)
Full Name
Recombinant Human Ephrin Type-A Receptor 4 (EPHA4), Partial
Gene Names
EPHA4; EK8; SEK; HEK8; TYRO1
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Pricing
$225/0.01 mg | $455/0.05 mg | $1,870/5x0.05 mg
Western Blot
(Western Blot analysis using Ret antibodyWestern Blot showing RET antibody used against truncated RET recombinant protein (1) and RET (aa658-1063)-hIgGFc transfected CHO-K1 cell lysate (2).)
Ret, Monoclonal Antibody (Cat# AAA533160)
Full Name
Ret antibody
Gene Names
RET; PTC; MTC1; HSCR1; MEN2A; MEN2B; RET51; CDHF12; CDHR16; RET-ELE1
Applications
EIA, WB
Pricing
$645/0.1 mL | $2,885/5x0.1 mL
Western Blot
(Western Blot analysis using TEC antibodyWestern Blot showing TEC antibody used against TEC (aa90-240)-hIgGFc transfected HEK293 cell lysate (1).)
TEC, Monoclonal Antibody (Cat# AAA831659)
Full Name
TEC antibody
Applications
EIA, WB
Pricing
$525/0.1 mL | $2,355/5x0.1 mL
Western Blot
(Western Blot analysis using BMX antibodyWestern Blot showing BMX antibody used against BMX (AA: 138-276)-hIgGFc transfected HEK293 cell lysate.)
BMX, Monoclonal Antibody (Cat# AAA831477)
Full Name
BMX antibody
Gene Names
BMX; ETK; PSCTK2; PSCTK3
Reactivity
Human
Applications
EIA, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Immunofluorescence (IF)
(Confocal immunofluorescence analysis of HEK293 cells trasfected with extracellular ERBB3 (aa22-369)-hIgGFc using ERBB3 antibody (green). Blue: DRAQ5 fluorescent DNA dye.)
ERBB3, Monoclonal Antibody (Cat# AAA5306014)
Full Name
Mouse monoclonal ERBB3 antibody
Gene Names
erbb3b; erbb3
Applications
EIA, IF, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Western Blot
(Western Blot analysis using Ret antibodyWestern Blot showing RET antibody used against truncated RET recombinant protein (1) and RET (aa658-1063)-hIgGFc transfected CHO-K1 cell lysate (2).)
Ret, Monoclonal Antibody (Cat# AAA831231)
Full Name
Ret antibody
Gene Names
RET; PTC; MTC1; HSCR1; MEN2A; MEN2B; RET51; CDHF12; CDHR16; RET-ELE1
Applications
EIA, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Immunohistochemistry (IHC)
(At 1/100 staining Human colorectal cancer by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the primary antibody at 4 degree C overnight. An HRP conjugated anti-Mouse antibody was used as the secondary antibody.)
p38 MAPK, Monoclonal Antibody (Cat# AAA9629034)
Full Name
p38 MAPK Monoclonal Antibody
Gene Names
MAPK14; RK; p38; CSBP; EXIP; Mxi2; CSBP1; CSBP2; CSPB1; PRKM14; PRKM15; SAPK2A; p38ALPHA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity-chromatography.
Pricing
$280/0.1 mL | $325/0.2 mL | $1,305/5x0.2 mL
MEK 5, Polyclonal Antibody (Cat# AAA222783)
Full Name
RABBIT ANTI RAT MEK 5 (pSer311/Thr315)
Gene Names
Map2k5; Mek5
Reactivity
Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Primate (Expected from Sequence), Xenopus (Expected from Sequence), Zebrafish (Expected from S
Applications
WB
Pricing
$625/0.1 mL | $2,670/5x0.1 mL
ASK1, Polyclonal Antibody (Cat# AAA221528)
Full Name
RABBIT ANTI HUMAN ASK1 (pSer83)
Gene Names
MAP3K5; ASK1; MEKK5; MAPKKK5
Applications
EIA, WB
Pricing
$280/0.05 mg | $1,110/5x0.05 mg
Western Blot (WB)
(Western Blot showing HCK antibody used against truncated HCK recombinant protein (1) and full-length HCK-GFP transfected CHO-K1 cell lysate (2).)
HCK, Monoclonal Antibody (Cat# AAA533028)
Full Name
HCK antibody
Applications
EIA, IHC, WB
Pricing
$645/0.1 mL | $2,885/5x0.1 mL
Protein Kinase C Inhibitor Peptide, Inhibitor (Cat# AAA655412)
Full Name
Protein Kinase C Inhibitor Peptide (RFARKGALRQKNV) (PKCI)
Gene Names
PRKCD; MAY1; PKCD; nPKC-delta
Purity
Highly Purified
97% (HPLC)
97% (HPLC)
Pricing
$665/1 mg | $2,975/5x1 mg
Western Blot
(Western Blot analysis using JAK2 antibodyWestern Blot showing JAK2 antibody used against THP-1 (1) cell lysate.)
JAK2, Monoclonal Antibody (Cat# AAA533367)
Full Name
JAK2 antibody
Gene Names
JAK2; JTK10; THCYT3
Applications
EIA, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Western Blot (WB)
(Western Blot showing ABL2 antibody used against HEK293T cells transfected with the pCMV6-ENTRY control (1) and pCMV6-ENTRY ABL2 cDNA (2).)
ABL2, Monoclonal Antibody (Cat# AAA830328)
Full Name
ABL2 antibody
Gene Names
ABL2; ARG; ABLL
Applications
EIA, IF, WB
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Testing Data
(specific activity)
Akt1, active, Active Protein (Cat# AAA635925)
Full Name
Akt1, active, Recombinant, Human (Rac PKa, PKBa)
Gene Names
TEK; TIE2; VMCM; TIE-2; VMCM1; CD202B
Purity
Highly Purified
70% (SDS-PAGE)
70% (SDS-PAGE)
Pricing
$675/0.01 mg | $3,040/5x0.01 mg
Western Blot
(Western Blot analysis using YES1 antibodyWestern Blot showing YES1 antibody used against truncated YES1-His recombinant protein (1) and full-length GFP-YES1 (aa1-543) transfected COS7 cell lysate (2).)
YES1, Monoclonal Antibody (Cat# AAA831219)
Full Name
YES1 antibody
Gene Names
Yes1; Yes; p61-Yes
Applications
EIA, WB
Pricing
$645/0.1 mL | $2,885/5x0.1 mL
TIE2, Recombinant Protein (Cat# AAA536569)
Full Name
TIE2 protein (Fc Chimera)
Applications
User optimized
Purity
> 90% pure
Pricing
$570/0.1 mg | $2,560/5x0.1 mg
Western Blot (WB)
(Western Blot showing ABL2 antibody used against truncated ABL2 recombinant protein.)
ABL2, Monoclonal Antibody (Cat# AAA831404)
Full Name
ABL2 antibody
Gene Names
ABL2; ARG; ABLL
Applications
EIA, IF, WB
Pricing
$525/0.1 mL | $2,355/5x0.1 mL
p38 MAPK, Polyclonal Antibody (Cat# AAA221795)
Full Name
RABBIT ANTI p38 MAPK (pThr180/Tyr182)
Gene Names
Mapk14; RK; Hog; p38; CRK1; CSBP; Exip; Mxi2; CSPB1; Csbp1; Csbp2; Prkm14; Prkm15; Sapk2A; p38Hog; p38alpha
Reactivity
Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human, Monkey (Expected from Sequence), Mouse (Expected from Sequence), Zebrafish (Expected from Sequence)
Applications
WB
Pricing
$625/0.1 mL | $2,670/5x0.1 mL
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human lung cancer (A), muscles (B) and breast cancer (C) using MUSK antibody with DAB staining.)
MuSK, Monoclonal Antibody (Cat# AAA532958)
Full Name
MuSK antibody
Gene Names
MUSK; CMS9
Applications
EIA, IF, IHC
Pricing
$605/0.1 mL | $2,715/5x0.1 mL
Western Blot (WB)
(Western Blot analysis of HEK293T cell lysates (5 ug) transfected with either recombinant BAIAP2 protein (Right) or empty vector (Left) detected with BAIAP2 antibody)
BAIAP2, Monoclonal Antibody (Cat# AAA533962)
Full Name
BAIAP2 antibody
Gene Names
HINT1; HINT; NMAN; PKCI-1; PRKCNH1
Applications
FC/FACS, IF, WB
Purity
BAIAP2 antibody was purified by affinity chromatography.
Pricing
$885/0.1 mL | $3,965/5x0.1 mL
JAK2, N-terminal GST tag, Active Protein (Cat# AAA637772)
Full Name
JAK2, Recombinant, Human, N-terminal GST tag (Janus Kinase 2)
Gene Names
jak2b; jak2; JAK2bCA
Reactivity
Human
Purity
80% by SDS-PAGE
Pricing
$675/0.01 mg | $3,040/5x0.01 mg
Chemical Structure
(Chemical structure of C16 (SIH-498), a PKR kinase inhibitor. CAS #: 608512-97-6. Molecular Formula: C13H8N4OS. Molecular Weight: 268.3 g/mol.)
C16, Small Molecule (Cat# AAA808197)
Full Name
C16
Purity
>=98% (HPLC)
Pricing
$190/5 mg | $380/25 mg | $1,470/5x25 mg | $640/5x5 mg
Testing Data
(3-(2-Imidazo[1,2-b]pyridazin-3-ylethynyl)-4-methyl-N-[4-[(4-methyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]benzamide; AP 24534; Iclusig)
Ponatinib, Biochemical (Cat# AAA6092139)
Full Name
Ponatinib
Purity
~90% by HPLC
Pricing
$185/10 mg | $250/25 mg | $335/50 mg | $420/100 mg | $600/250 mg | $2,695/5x250 mg
RAF-1, Polyclonal Antibody (Cat# AAA221524)
Full Name
RABBIT ANTI RAF-1 (pSer642)
Reactivity
Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human (Expected from Sequence), Mouse (Expected from Sequence), Primate (Expected from Sequence)
Applications
WB
Pricing
$625/0.1 mL | $2,670/5x0.1 mL
ERK/MAPK, Polyclonal Antibody (Cat# AAA221791)
Full Name
RABBIT ANTI ERK/MAPK (pThr202/pTyr204)
Gene Names
Mapk3; p44; ERK1; ERT2; MNK1; Erk-1; Esrk1; MAPK1; Prkm3; p44erk1; p44mapk
Reactivity
Bovine (Expected from Sequence), Chicken (Expected from Sequence), Dog (Expected from Sequence), Human, Monkey (Expected from Sequence), Mouse (Expected from Sequence), Xenopus (Expected from Sequence), Zebrafish (Expected from Sequence)
Applications
WB
Pricing
$625/0.1 mL | $2,670/5x0.1 mL
Protein Kinase C Inhibitor, zeta, Pseudosubstrate, Myristoylated, Inhibitor (Cat# AAA655385)
Full Name
Protein Kinase C Inhibitor, zeta, Pseudosubstrate, Myristoylated
Gene Names
SRC; ASV; SRC1; c-SRC; p60-Src
Purity
Highly Purified
~90% by HPLC and MS analysis
~90% by HPLC and MS analysis
Pricing
$325/1 mg | $1,460/5x1 mg
Testing Data
(ACK1 activity)
ACK1, N-terminal GST tag, Active Protein (Cat# AAA635896)
Full Name
ACK1, N-terminal GST tag, Recombinant, Human (TNK2, Tyrosine Kinase, non-receptor 2, Tyrosine Kinase non-receptor protein 2, ACK, ACK1, Activated CDC42 kinase 1, FLJ44758, FLJ45547, p21cdc42Hs)
Gene Names
TNK2; ACK; ACK1; ACK-1; p21cdc42Hs
Purity
Purified
Purified 70%
Purified 70%
Pricing
$750/0.01 mg | $3,365/5x0.01 mg
p42/44 MAPK, Polyclonal Antibody (Cat# AAA835454)
Full Name
p42/44 MAPK antibody
Applications
IHC, IP, WB
Purity
p42/44 MAPK antibody was purified by affinity chromatography
Pricing
$495/0.1 mg | $2,225/5x0.1 mg
Testing Data
()
Emodin, p56lck Tyrosine Kinase Inhibitor, Biochemical (Cat# AAA6019456)
Full Name
Emodin, p56lck Tyrosine Kinase Inhibitor (1,3,8-Trihydroxy-6-Methylanthracene-9,10-Dione)
Purity
Highly Purified
~98% (HPLC)
~98% (HPLC)
Pricing
$335/25 mg | $550/100 mg | $2,455/5x100 mg
Western Blot
(Western Blot analysis using SYK antibodyWestern Blot showing SYK antibody used against truncated SYK-His recombinant protein (1) and PMA induced THP-1 cell lysate (2).)
SYK, Monoclonal Antibody (Cat# AAA830791)
Full Name
SYK antibody
Gene Names
Syk; Sykb
Applications
EIA, WB
Pricing
$675/0.1 mL | $3,020/5x0.1 mL
DDR1, Polyclonal Antibody (Cat# AAA535457)
Full Name
DDR1 antibody
Reactivity
Human
Applications
IHC
Purity
DDR1 antibody was purified by affinity chromatography.
Pricing
$885/0.05 mg | $3,965/5x0.05 mg
Immunofluorescence (IF)
(Immunofluorescence staining of methanol-fixed Hela cells using JNK1/JNK2 (Phospho-Thr183/Tyr185) antibody)
JNK1/JNK2, Polyclonal Antibody (Cat# AAA835724)
Full Name
JNK1/JNK2 antibody
Applications
IF, WB
Purity
JNK1/JNK2 antibody was purified by immunoaffinity chromatography.
Pricing
$375/0.05 mg | $1,675/5x0.05 mg
TIE2, Polyclonal Antibody (Cat# AAA534869)
Full Name
TIE2 antibody
Reactivity
Human
Applications
EIA, IF, IHC, WB
Purity
TIE2 antibody was purified by affinity chromatography.
Pricing
$885/0.1 mg | $3,970/5x0.1 mg
PTK2, Polyclonal Antibody (Cat# AAA535612)
Full Name
PTK2 antibody
Gene Names
PTK2; FAK; FADK; FAK1; FRNK; PPP1R71; p125FAK; pp125FAK
Reactivity
Human
Applications
IHC
Purity
PTK2 antibody was purified by affinity chromatography.
Pricing
$885/0.05 mg | $3,965/5x0.05 mg
Erk1/2, Polyclonal Antibody (Cat# AAA837439)
Full Name
Phospho-Erk1/2 antibody
Applications
IHC, IP, WB
Purity
Phospho-Erk1/2 antibody was purified by affinity chromatography
Pricing
$590/0.1 mg | $2,650/5x0.1 mg
Western Blot (WB)
(Western Blot showing EphB3 antibody used against truncated EphB3-His recombinant protein.)
EphB3, Monoclonal Antibody (Cat# AAA830137)
Full Name
EphB3 antibody
Gene Names
EPHB3; ETK2; HEK2; TYRO6
Applications
EIA, IHC, WB
Pricing
$645/0.1 mL | $2,885/5x0.1 mL
