Dilution Information
Rabbit anti-Human Collagen Type IV Monoclonal Antibody
Collagen Type IV (RBT-COL4)
Reactivity
Human
Synonyms
Collagen Type IV; Monoclonal Antibody; Collagen Type IV (RBT-COL4); collagen iv; collagen 4; anti-collagen; collagen-iv; collagen-4; anti-collagen-iv; anti-collagen-4; anti-Collagen Type IV antibody
Host
Rabbit
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG
Clone Number
RBT-COL4
Form/Format
Paraffin, Frozen
Collagen IV is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Collagen IV is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Purified human placental extract.
Control
Muscle, Lung, Breast, Placenta, Testis, Transitional Cell Carcinoma, T Cell Lymphoblastic Lymphoma
Localization
Cytoplasmic, Membranous
Product Note
Collagen Type IV antibody requires the use of ImmunoDNA Digestor or similar Proteinase K based product as antigen retriever.
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(Collagen IV Antibody Immunohistochemistry on an FFPE Lung Adenocarcinoma Tissue)
Immunohistochemistry (IHC)
(Collagen IV Antibody Immunohistochemistry on an FFPE Lung Adenocarcinoma Tissue)
Immunohistochemistry (IHC)
(Collagen IV Antibody Immunofluorescence on a FFPE Kidney Tissue)
Immunohistochemistry (IHC)
(Collagen IV Antibody Immunofluorescence on a FFPE Kidney Tissue)
Related Product Information for anti-Collagen Type IV antibody
Collagen is the main protein of connective tissue in animals and the most abundant protein in mammals, making up about 25% of the total protein content. Collagen IV is a major constituent of the basement membranes, along with laminins and enactins. It is composed of the alpha 1 IV chain and alpha 2 IV chain in a 2:1 ratio. It can form insoluble fibers with high tensile strength.
Normal tissue immunostained with this Collagen IV antibody is consistent with the sites of mesenchymal elements and epithelial basal laminae. Collagen IV antibody is useful in detecting the loss of parts of basement membrane in carcinomas. Collagen IV can also be useful in the classification of soft tissue tumors; schwannomas, leiomyomas, and their well-differentiated malignant counterparts usually immunoreact to this antibody. The vascular nature of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma can be observed with this antibody.
Normal tissue immunostained with this Collagen IV antibody is consistent with the sites of mesenchymal elements and epithelial basal laminae. Collagen IV antibody is useful in detecting the loss of parts of basement membrane in carcinomas. Collagen IV can also be useful in the classification of soft tissue tumors; schwannomas, leiomyomas, and their well-differentiated malignant counterparts usually immunoreact to this antibody. The vascular nature of neoplasms, hemangiopericytoma, angiosarcoma and epithelioid hemangioendothelioma can be observed with this antibody.
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Product Notes
The Collagen Type IV (Catalog #AAA370542) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Collagen Type IV (RBT-COL4) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Collagen Type IV, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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