Dilution Information
Rabbit Somatostatin Receptor 2/SSTR2 Monoclonal Antibody | anti-2/SSTR2 antibody
Somatostatin Receptor 2/SSTR2 (EP149)
Reactivity
Human, Mouse, Rat
Synonyms
Somatostatin Receptor 2/SSTR2; Monoclonal Antibody; Somatostatin Receptor 2/SSTR2 (EP149); somatostatin receptor 2; sstr2; anti-somatostatin receptor 2; anti-sstr2;; anti-2/SSTR2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG
Clone Number
EP149
Form/Format
Paraffin, Frozen
Somatostatin Receptor 2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Somatostatin Receptor 2 is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Synthetic peptide corresponding to residues on the C-terminus of the human SSTR2 protein.
Control
Placenta, Brain, Testis, Prostate, Papillary Thyroid Carcinoma, Transitional Cell Carcinoma
Localization
Cytoplasmic, Membranous
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(Somatostatin Receptor 2 Antibody Immunohistochemistry on an FFPE Lung Adenocarcinoma Tissue)
Immunohistochemistry (IHC)
(Somatostatin Receptor 2 Antibody Immunohistochemistry on an FFPE Lung Adenocarcinoma Tissue)
Related Product Information for anti-2/SSTR2 antibody
Somatostatin Receptor 2 (SSTR2) is one of five subtypes of the somatostatin receptors, which belong to the superfamily of G protein-coupled receptors (GPCRs). Somatostatin receptor 2 is encoded by the SSTR2 gene, located on chromosome 17q25.1. SSTR2. SSTR2 becomes activated by the hormone somatostatin (SST), which is an inhibitor of hormone secretion and gastrointestinal function. SST and its receptor subtypes also prevent angiogenesis and have anti-proliferative effects on healthy and cancerous cells.
Somatostatin Receptors have been reported to be highly expressed in a wide variety of human tumors. High somatostatin receptor 2 antibody expression was found via IHC in neuroblastomas, medulloblastomas, paragangliomas, small cell lung cancers, meningiomas, and breast cancers. One study reported a highly specific and increased expression of somatostatin receptor 2 antibody in a large series of neural and neuroendocrine tumors. Another study investigating patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) demonstrated the correlation between decreased immunohistochemical staining and advanced stage of tumors. Additionally, an improved survival of patients with high SSTR2 expression was found, indicating the usefulness of SSTR2 as a potential prognostic marker for GEP-NEN.
Somatostatin Receptors have been reported to be highly expressed in a wide variety of human tumors. High somatostatin receptor 2 antibody expression was found via IHC in neuroblastomas, medulloblastomas, paragangliomas, small cell lung cancers, meningiomas, and breast cancers. One study reported a highly specific and increased expression of somatostatin receptor 2 antibody in a large series of neural and neuroendocrine tumors. Another study investigating patients with gastroenteropancreatic neuroendocrine neoplasm (GEP-NEN) demonstrated the correlation between decreased immunohistochemical staining and advanced stage of tumors. Additionally, an improved survival of patients with high SSTR2 expression was found, indicating the usefulness of SSTR2 as a potential prognostic marker for GEP-NEN.
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Product Notes
The 2/SSTR2 (Catalog #AAA370514) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Somatostatin Receptor 2/SSTR2 (EP149) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "Somatostatin Receptor 2/SSTR2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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