Testing Data
Mammalian Arylamine N-acetyltransferase Assay Kit
Arylamine N-acetyltransferase Activity Assay Kit (Fluorometric)
Reactivity
Mammalian
Synonyms
Arylamine N-acetyltransferase; Arylamine N-acetyltransferase Activity Assay Kit (Fluorometric); Arylamine N-acetyltransferase Fluorometric Activity Assay; Arylamine N-acetyltransferase Fluorometric Kit; Arylamine N-acetyltransferase Activity Assay Kit; Arylamine N-acetyltransferase Activity Kit; Arylamine acetyltransferase; Arylamine N-acetyltransferase Fluorometric Activity Kit; Arylamine N-acetyltransferase Fluorometric Assay; Arylamine N-acetyltransferase Assay Kit (Fluorometric); Arylamine N-acetyltransferase Assay; Arylamine N-acetyltransferase Activity Kit (Fluorometric); Arylamine N-acetyltransferase Activity Assay; Arylamine N-acetyltransferase Fluorometric Assay Kit; Arylamine N-acetyltransferase Fluorometric Activity Assay Kit; Arylamine N-acetyltransferase Activity Assay (Fluorometric); Arylamine N-acetyltransferase assay kit
Reactivity
Mammalian
Samples
S9 fractions, Recombinant enzyme, Purified protein
Detection Method
Fluorescence: Ex/Em 360/440nm
Features & Benefits
Measurement of NAT activity
Preparation and Storage
Upon arrival, store the kitat -20 degree C, protected from light. Briefly centrifuge the small vials before opening. Read the entire protocol before performing the assay. Components are stable for at least three months.
Shelf life: ~12 months
Shelf life: ~12 months
Testing Data
Testing Data
Related Product Information for Arylamine N-acetyltransferase assay kit
Arylamine N-acetyltransferases (NATs, EC 2.3.1.5) are a group of cytosolic, conjugating enzymes involved in phase II xenobiotic metabolism. They transfer an acetyl group from acetyl Coenzyme A to a xenobiotic acceptor substrate. There are two main isoforms, NAT1 and NAT2, which share about 81% amino acid sequence homology. NAT1 is widely expressed in all tissues whereas NAT2 is present primarily, in the liver and intestine. In addition to its role in xenobiotic metabolism, NAT1 plays an important role in folate metabolism. NAT2 is a polymorphic enzyme wherein the slow acetylator phenotype of NAT2 has been linked to urinary bladder cancer whereas the rapid acetylator phenotype has been linked to colorectal cancer. The slow acetylator phenotype has also been widely linked with toxicity due to isoniazid: a widely used tuberculosis drug. Arylamine N-acetyltransferase Activity Assay Kit is a simple, one step plate based assay that measures a fluorescent product. It can measure both NAT1 and NAT2 activity and can detect as low as 1 uU in samples.
Product Categories/Family for Arylamine N-acetyltransferase assay kit
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Product Notes
The Mammalian Arylamine N-acetyltransferase (Catalog #AAA849605) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849605 Assay Kit recognizes Mammalian Arylamine N-acetyltransferase. It is sometimes possible for the material contained within the vial of "Arylamine N-acetyltransferase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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