NCBI and Uniprot Product Information
Uniprot Description
PXDNL: Isoform PMR1: Endonuclease selectively degrading some target mRNAs while they are engaged by translating ribosomes, among which albumin and beta-globin mRNAs. Belongs to the peroxidase family. XPO subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Oxidoreductase; Secreted; EC 1.11.1.7
Chromosomal Location of Human Ortholog: 8q11.22-q11.23
Cellular Component: extracellular space
Molecular Function: heme binding; peroxidase activity
Biological Process: hydrogen peroxide catabolic process
Research Articles on PXDNL
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Product Notes
The PXDNL pxdnl (Catalog #AAA1271335) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGCTCATGC ACTGGGGCTG GTTTCTAGAG CACGACTTGG ACCACACAGT GCCTGCGCTG AGCACAGCCC GCTTCTCGGA TGGGCGGCCG TGCAGCTCCG TCTGCACCAA CGACCCTCCT TGTTTCCCCA TGAACACCCG GCACGCCGAC CCCCGGGGCA CCCACGCGCC CTGCATGCTC TTCGCGCGCT CCAGCCCCGC GTGTGCCAGC GGCCGTCCCT CTGCGACGGT GGATTCAGTC TATGCACGAG AGCAGATCAA CCAGCAAACA GCCTACATCG ATGGCTCCAA CGTTTACGGG AGCTCGGAGC GGGAATCCCA GGCTCTCAGA GACCCTTCGG TGCCTCGGGG TCTCCTGAAG ACAGGCTTTC CTTGGCCTCC CTCCGGAAAG CCCTTATTGC CCTTTTCTAC AGGCCCACCC ACCGAGTGCG CGCGACAGGA GCAGGAGAGC CCCTGTTTCC TGGCCGGGGA CCACCGGGCC AACGAGCATC TGGCTCTGGC CGCCATGCAC ACCCTGTGGT TCCGGGAACA CAACAGGGTG GCCACGGAGC TGTCCGCCCT GAACCCCCAC TGGGAGGGAA ACACGGTTTA CCAGGAAGCC AGGAAGATCG TGGGCGCGGA GCTGCAGCAC ATCACCTACA GCCACTGGCT GCCTAAGGTC CTGGGGGACC CTGGCACTAG GATGCTGAGG GGTTACCGAG GCTACAACCC CAACGTGAAT GCAGGCATCA TTAACTCTTT TGCTACTGCA GCCTTTAGAT TTGGCCACAC ATTAATCAAT CCTATTCTTT ACCGACTGAA TGCCACCTTA GGTGAAATTT CCGAAGGCCA CCTTCCGTTC CATAAAGCGC TCTTTTCACC GTCCAGAATA ATCAAGGAAG GTGGGATAGA CCCGGTTCTC CGGGGGCTGT TTGGCGTGGC TGCTAAATGG CGGGCACCCT CCTACCTTCT CAGTCCTGAG CTGACCCAGA GGCTCTTCTC CGCGGCTTAT TCTGCGGCCG TGGATTCGGC TGCCACCATC ATTCAAAGGG GTAGAGACCA CGGGATCCCA CCATATGTTG ACTTCAGAGT TTTCTGTAAT TTGACTTCAG TTAAGAACTT TGAGGATCTT CAAAATGAAA TTAAAGATTC AGAGATTAGA CAAAAACTGA GAAAGTTGTA CGGCTCTCCA GGTGACATTG ACCTCTGGCC CGCCCTTATG GTTGAAGACC TGATTCCTGG TACAAGAGTG GGACCAACAC TTATGTGCCT GTTTGTTACC CAGTTTCAGC GGCTAAGAGA TGGAGATAGG TTCTGGTATG AAAACCCTGG AGTATTTACC CCGGCACAAC TCACTCAGCT GAAGCAGGCG TCCCTGAGCC GGGTGCTTTG TGACAATGGT GACAGCATTC AGCAAGTGCA GGCTGATGTC TTTGTAAAGG CAGAATACCC ACAGGATTAC CTGAACTGCA GCGAGATCCC GAAGGTGGAC CTGCGAGTGT GGCAAGACTG CTGTGCAGAT AAACAAGCTG GAGGCACGCC TGAGGCAGGC AGGGTGTACA GATGTTAG. It is sometimes possible for the material contained within the vial of "PXDNL, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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