Map
DUSP11 cdna clone
Human DUSP11 cDNA Clone
Map
Map
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product is localized to the nucleus and binds directly to RNA and splicing factors, and thus it is suggested to participate in nuclear mRNA metabolism. [provided by RefSeq, Sep 2008]
Uniprot Description
DUSP11: Possesses RNA 5'-triphosphatase and diphosphatase activities, but displays a poor protein-tyrosine phosphatase activity. Binds to RNA. May participate in nuclear mRNA metabolism. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis; Protein phosphatase, dual-specificity; EC 3.1.3.-; Phosphatase (non-protein)
Chromosomal Location of Human Ortholog: 2p13.1
Cellular Component: nuclear speck; nucleus
Molecular Function: phosphoric monoester hydrolase activity; polynucleotide 5'-phosphatase activity; protein tyrosine phosphatase activity; RNA binding
Biological Process: protein amino acid dephosphorylation; RNA metabolic process; RNA processing
Research Articles on DUSP11
Similar Products
Product Notes
The DUSP11 dusp11 (Catalog #AAA1273489) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGAGCCAGT GGCATCATCC CCGCAGTGGC TGGGGCCGGA GACGCGACTT TTCAGGACGC TCCTCAGCCA AGAAGAAGGG CGGAAACCAC ATCCCCGAAA GGTGGAAAGA CTATCTCCCA GTTGGACAGC GGATGCCTGG GACTCGTTTC ATTGCTTTCA AAGTTCCTTT GCAAAAGAGT TTTGAAAAGA AACTTGCTCC AGAAGAATGC TTTTCCCCTT TGGATCTTTT TAACAAAATC CGAGAACAAA ATGAAGAACT TGGACTGATT ATTGATTTAA CATATACTCA ACGCTATTAT AAACCAGAGG ATTTGCCAGA AACTGTTCCT TACTTAAAAA TTTTTACAGT TGGACATCAA GTGCCTGATG ATGAGACTAT TTTTAAATTC AAACACGCTG TTAATGGGTT TTTGAAAGAA AATAAAGATA ATGATAAACT TATTGGTGTC CACTGTACCC ATGGTTTAAA CAGGACTGGC TACCTCATTT GCATATATTT GATTGATGTA GAAGGCGTGA GGCCAGATGA TGCAATTGAA TTATTCAATA GGTGCCGGGG ACATTGCTTA GAAAGACAAA ACTACATTGA AGACCTTCAG AATGGTCCTA TCAGAAAGAA TTGGAATTCC AGTGTACCCA GGTCAAGTGA TTTTGAAGAC TCAGCACATC TCATGCAACC AGTCCACAAT AAGCCTGTTA AACAAGGACC TAGGTATAAT CTACATCAGA TCCAGGGTCA CTCAGCTCCT CGACATTTCC ACACCCAGAC CCAAAGTTTG CAACAATCAG TCAGAAAATT TTCAGAGAAT CCACATGTTT ACCAGAGACA CCATCTCCCT CCTCCTGGTC CCCCTGGAGA GGACTATTCA CACAGGAGGT ATTCTTGGAA TGTGAAGCCC AATGCCAGTC GGGCAGCCCA GGATAGAAGA AGGTGGTATC CTTATAATTA CTCCAGACTC TCCTATCCAG CCTGTTGGGA ATGGACCCAG TGA. It is sometimes possible for the material contained within the vial of "DUSP11, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
