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Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Rat brain tissue and Mouse brain tissue lysates, Primary antibody: 162972(PTOV1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)

Rabbit PTOV1 Polyclonal Antibody | anti-PTOV1 antibody

PTOV1 Rabbit pAb

Gene Names
PTOV1; ACID2; PTOV-1
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
PTOV1; Polyclonal Antibody; PTOV1 Rabbit pAb; ACID2; PTOV-1; anti-PTOV1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-PTOV1 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human PTOV1
Conjugation
Unconjugated
Molecular Function
This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants.
Modification
Unmodified
Cell Position
Cell membrane, Cytoplasm, Membrane, Nucleus
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Rat brain tissue and Mouse brain tissue lysates, Primary antibody: 162972(PTOV1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)

Western Blot (WB) (Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane 1-2: Rat brain tissue and Mouse brain tissue lysates, Primary antibody: 162972(PTOV1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 40 seconds)

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 162972(PTOV1 Antibody) at dilution 1/25. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using 162972(PTOV1 Antibody) at dilution 1/25. (Original magnification: ×200))

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 162972(PTOV1 Antibody) at dilution 1/25. (Original magnification: ×200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using 162972(PTOV1 Antibody) at dilution 1/25. (Original magnification: ×200))
Product Categories/Family for anti-PTOV1 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,145 Da
NCBI Official Full Name
prostate tumor-overexpressed gene 1 protein isoform 1
NCBI Official Synonym Full Names
prostate tumor overexpressed 1
NCBI Official Symbol
PTOV1
NCBI Official Synonym Symbols
ACID2; PTOV-1
NCBI Protein Information
prostate tumor-overexpressed gene 1 protein; activator interaction domain-containing protein 2
UniProt Protein Name
Prostate tumor-overexpressed gene 1 protein
UniProt Gene Name
PTOV1
UniProt Synonym Gene Names
ACID2; PTOV-1
UniProt Entry Name
PTOV1_HUMAN

Uniprot Description

PTOV1: May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation. Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 19q13.33

Cellular Component: nucleus; perinuclear region of cytoplasm; plasma membrane

Biological Process: regulation of transcription, DNA-dependent; transcription, DNA-dependent

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Product Notes

The PTOV1 ptov1 (Catalog #AAA4754966) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PTOV1 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PTOV1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the PTOV1 ptov1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PTOV1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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