Testing Data
General Glucosylceramidase Assay Kit
Glucosylceramidase Activity Assay Kit (Fluorometric)
Reactivity
General
Synonyms
Glucosylceramidase; Glucosylceramidase Activity Assay Kit (Fluorometric); Glucosylceramidase Assay Kit (Fluorometric); Glucosylceramidase Activity Assay; Glucosylceramidase beta; Glucosylceramidase Activity Assay (Fluorometric); Glucosylceramidase Activity Kit; Glucosylceramidase Activity Assay Kit; Glucosylceramidase assay kit
Reactivity
General
Samples
Tissue Homogenates: Spleen, etc
Cell Lysates: MDA-MB-231 Cell Lysates, 3T3Cell Lysates,etc
Cell Lysates: MDA-MB-231 Cell Lysates, 3T3Cell Lysates,etc
Detection Method
Fluoroescence: Ex/Em 360/445nm
Features & Benefits
Screening for Gaucher Disease
Measurement of Glucosylceramidase activity in various tissues/cells
To monitor Glucosylceramidase activity
Measurement of Glucosylceramidase activity in various tissues/cells
To monitor Glucosylceramidase activity
Preparation and Storage
Store at -20 degree C
Shelf life: ~12 months
Shelf life: ~12 months
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for Glucosylceramidase assay kit
Lysosomal glucosylceramidase beta also known as acid beta-glucosidase (E.C. 3.2.1.45) is a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide (GC). The enzyme plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, it participates in the PKC-activated salvage pathway of ceramide formation. Glucosylceramidase also plays a role in cholesterol metabolism. It may catalyze the glucosylation of cholesterol through a transglucosylation reaction that transfers glucose from glucosylceramide to cholesterol. Deficiency of Glucosylceramidase results in the accumulation of GC in lysosomes. This leads to Gaucher disease, an inherited disorder that affects many organs and tissues. Glucosylceramidase Activity Assay Kit provides a simple, rapid way to monitor Glucosylceramidase activity in a wide variety of biological samples. In this kit, Glucosylceramidase cleaves a specific synthetic substrate and releases a fluorophore, which can be easily quantified (Ex/Em=360/445 nm). The assay is specific, sensitive and can detect as low as 0.2 uU of Glucosylceramidase activity in variety of samples.
Product Categories/Family for Glucosylceramidase assay kit
Similar Products
Product Notes
The General Glucosylceramidase (Catalog #AAA849579) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849579 Assay Kit recognizes General Glucosylceramidase. It is sometimes possible for the material contained within the vial of "Glucosylceramidase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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