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Chemical Structure (Chemical structure of Puromycin HCl (SIH-248), a Translation inhibitor. CAS #: 58-58-2. Molecular Formula: C22H29N7O5 x 2HCl. Molecular Weight: 544.43 g/mol.)

Puromycin Small Molecule

Puromycin HCl

Purity
>98% (TLC); NMR (Conforms)
Synonyms
Puromycin; Puromycin HCl; Translation inhibitor; 3'-Deoxy-N; N-dimethyl-3'-[(O-methyl-L-tyrosyl)amino]adenosine; Puromycin small molecule
Ordering
For Research Use Only!
Host
Synthetic
Purity/Purification
>98% (TLC); NMR (Conforms)
Form/Format
Off-white powder
Solubility
May be dissolved in DMSO (50 mg/ml); or water (50 mg/ml)
CAS Number
58-58-2
Molecular Formula
C22H29N7O5-2HCl
SMILES
CN(C)C1=NC=NC2=C1N=CN2[C@H]3[C@@H]([C@@H]([C@H](O3)CO)NC(=O)[C@H](CC4=CC=C(C=C4)OC)N)O
InChI
1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5
InChI Key
RXWNCPJZOCPEPQ-WABMVTPESA-N
PubChem CID
5891
PubMed ID
25756236; 24637494
Preparation and Storage
Store at -20 degree C.

Chemical Structure

(Chemical structure of Puromycin HCl (SIH-248), a Translation inhibitor. CAS #: 58-58-2. Molecular Formula: C22H29N7O5 x 2HCl. Molecular Weight: 544.43 g/mol.)

Chemical Structure (Chemical structure of Puromycin HCl (SIH-248), a Translation inhibitor. CAS #: 58-58-2. Molecular Formula: C22H29N7O5 x 2HCl. Molecular Weight: 544.43 g/mol.)
Related Product Information for Puromycin small molecule
Puromycin is an antibiotic that is a protein synthesis inhibitor that causes premature chain termination during translation taking place in the ribosome. Part of the molecule resembles the 3' end of the tRNA. It enters the A site and transfers to the growing chain, causing the premature release. It is not selective for either prokaryotes or eukaryotes.
Product Categories/Family for Puromycin small molecule
References
1.  Azzam and Algranati. (1973) Proc Natl Acad Sci. 70: 3866.

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Product Notes

The Puromycin (Catalog #AAA807986) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Puromycin, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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