Structure
Puromycin Dihydrochloride Biochemical
Puromycin Dihydrochloride
Purity
>=98% by HPLC
Synonyms
Puromycin Dihydrochloride; 3?-[alpha-Amino-p-methoxyhydrocinnamamido]-3?-deoxy-N; N-dimethyladenosine dihydrochloride; Puromycin Dihydrochloride biochemical
Purity/Purification
>=98% by HPLC
Form/Format
Appearance: White to off-white solid
CAS Number
58-58-2
Structure Available?
Yes
Salt Form
No
Cell-Permeable?
No
MDL Number
MFCD00012691
PubChem CID
16757772
Solubility/Reconstitution Instructions
H?O (~50 mg/ml)
SMILES
CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)NC(=O)C(CC4=CC=C(C=C4)OC)N)O.Cl.Cl
InChi
InChI=1S/C22H29N7O5.2ClH/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12;;/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32);2*1H
InChi Key
MKSVFGKWZLUTTO-UHFFFAOYSA-N
Handling
Protect from air and moisture
Preparation and Storage
At -20 degree C
Shelf Life: 24 months
Shelf Life: 24 months
Structure
Structure
Related Product Information for Puromycin Dihydrochloride biochemical
Background: A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to puromycin is conferred by the puromycin N-acetyl-transferase gene (pac) from Streptomyces. Puromycin has a fast mode of action, causing rapid cell death at low antibiotic concentrations. Adherent mammalian cells are sensitive to concentrations of 2 to 5 ug/ml, while cells in suspension are sensitive to concentrations as low as 0.5 to 2 ug/ml.
Product Categories/Family for Puromycin Dihydrochloride biochemical
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Product Notes
The Puromycin Dihydrochloride (Catalog #AAA843302) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Puromycin Dihydrochloride, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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