Chemical Structure
(Chemical structure of Carnosic acid (SIH-362), a REDOX& GSH induction. CAS #: 3650-09-7. Molecular Formula: C20H28O4. Molecular Weight: 332.43 g/mol.)
Carnosic acid Small Molecule
Carnosic acid
Purity
>=95% (HPLC); NMR(Conforms)
Synonyms
Carnosic acid; PPARgamma activator; (4aR; 10aS)-5; 6-Dihydroxy-7-isopropyl-1; 1-dimethyl-1; 3; 4; 9; 10; 10a-hexahydro-2H-phenanthrene-4a-carboxylic acid; Carnosic acid small molecule
Host
Synthetic
Purity/Purification
>=95% (HPLC); NMR(Conforms)
Form/Format
Off white to yellow solid
Solubility
Soluble in DMSO (50 mg/ml)
Molecular Formula
C20H28O4
SMILES
CC(C)C1=C(C(=C2C(=C1)CC[C@@H]3[C@@]2(CCCC3(C)C)C(=O)O)O)O
InChI
1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1
InChI Key
QRYRORQUOLYVBU-VBKZILBWSA-N
PubChem CID
65126
Preparation and Storage
Store at -20 degree C.
Chemical Structure
(Chemical structure of Carnosic acid (SIH-362), a REDOX& GSH induction. CAS #: 3650-09-7. Molecular Formula: C20H28O4. Molecular Weight: 332.43 g/mol.)
Chemical Structure
(Chemical structure of Carnosic acid (SIH-362), a REDOX& GSH induction. CAS #: 3650-09-7. Molecular Formula: C20H28O4. Molecular Weight: 332.43 g/mol.)
Related Product Information for Carnosic acid small molecule
Carnosic acid is a benzenediol abietane diterpene naturally extracted from rosemary (Rosmarinus officinalis) and sage (Saliva officinalis). It is a potent antioxidant that inhibits NADH or NADPH induced lipid peroxidation by acting as a free radical scavenger (1). It has been found to increase cellular levels of glutathione (GSH) and prevent 6-hydroxydopamine-induced cell death in SH-SY5Y cells (2). Carnosic acid-stimulation of GSH also inhibits adipocyte differentiation (3). It has also been found to induce apoptosis (4) and inhibit the proliferation and migration of various tumor cell lines (5).
Product Categories/Family for Carnosic acid small molecule
References
1. Schwarz K., Ternes W. (1992) Zeitschrift für Lebensmittel-Untersuchung und -Forschung. 195 (2): 99-103. 2. Chen J.H., et al. Chem. (2012) Res. Toxicol 25:1893. 3. Takahashi T., et al. (2009) Biochem. Biophys. Res. Commun. 382:549. 4. Kar S., et al. (2012) Apoptosis. 17:1735. 5. Barni M.V., et al. (2012) Oncol. Rep. 27:1041.
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Product Notes
The Carnosic acid (Catalog #AAA808066) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Carnosic acid, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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