Search results for " Co stimulation"

HOP, Recombinant Protein (Cat# AAA806900)

Full Name

Recombinant Human HOP

Gene Names

STIP1; HOP; P60; STI1; STI1L; HEL-S-94n; IEF-SSP-3521

Reactivity

Human

Applications

WB

Pricing

$285/0.05 mg | $395/0.1 mg | $2,250/10x0.1 mg | $1,560/5x0.1 mg | $1,055/5x0.05 mg | $555/2x0.1 mg

p23, Recombinant Protein (Cat# AAA806950)

Full Name

Recombinant Human p23

Gene Names

PTGES3; P23; TEBP; cPGES

Reactivity

Human

Applications

WB

Pricing

$330/0.05 mg | $455/0.1 mg | $2,770/10x0.1 mg | $1,820/5x0.1 mg | $1,250/5x0.05 mg | $665/2x0.1 mg

SMAD3, Blocking Peptide (Cat# AAA9219988)

Full Name

SMAD3 Antibody (Center) Blocking peptide

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

IL10, Active Protein (Cat# AAA5304240)

Full Name

IL10 protein

Gene Names

IL10; CSIF; TGIF; GVHDS; IL-10; IL10A

Purity

> 98% pure
IL10 protein was purified using a a proprietary chromatographic technique.

Pricing

$395/0.01 mg | $1,770/5x0.01 mg

PTRF, Blocking Peptide (Cat# AAA9226877)

Full Name

PTRF Antibody (N-term) Blocking Peptide

Gene Names

PTRF; CGL4; CAVIN; CAVIN1; FKSG13; cavin-1

PTRF, Blocking Peptide (Cat# AAA9226878)

Full Name

PTRF Antibody (C-term) Blocking Peptide

Gene Names

PTRF; CGL4; CAVIN; CAVIN1; FKSG13; cavin-1

SMAD3 (S213), Blocking Peptide (Cat# AAA9225068)

Full Name

Phospho-SMAD3(S213) Antibody Blocking peptide

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Smad3, Blocking Peptide (Cat# AAA9229835)

Full Name

Smad3 Blocking Peptide (Center)

Gene Names

Smad3; Madh3; AU022421

IL10, Active Protein (Cat# AAA5304114)

Full Name

IL10 protein

Gene Names

IL10; CSIF; TGIF; GVHDS; IL-10; IL10A

Purity

> 98% pure
IL10 protein was purified using a a proprietary chromatographic technique.

Pricing

$370/0.01 mg | $1,650/5x0.01 mg

SMAD3, Blocking Peptide (Cat# AAA9229783)

Full Name

SMAD3 Blocking Peptide (Center)

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Smad3, Blocking Peptide (Cat# AAA9229870)

Full Name

Smad3 Blocking Peptide (Center)

Gene Names

Smad3; Madh3; AU022421

IL7, Active Protein (Cat# AAA5304042)

Full Name

IL7 protein

Purity

> 98% pure
IL7 protein was purified using a a proprietary chromatographic technique.

Pricing

$385/0.01 mg | $1,730/5x0.01 mg

SMAD3-S208, Blocking Peptide (Cat# AAA9228529)

Full Name

SMAD3-S208 Antibody Blocking Peptide

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

SMAD3 (S208), Blocking Peptide (Cat# AAA9225067)

Full Name

Phospho-SMAD3(S208) Antibody Blocking peptide

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

IL18, Active Protein (Cat# AAA5308747)

Full Name

Purified recombinant Human IL18 protein

Gene Names

IL18; IGIF; IL-18; IL-1g; IL1F4

Purity

> 98% pure
Purified using a proprietary chromatographic technique.

Pricing

$415/0.025 mg | $1,855/5x0.025 mg

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Testing Data (Surface Staining of buffy coat differentiated monocytes by Mouse anti Human CD169:RPE )

Testing Data (PE conjugated Mouse anti CD169 antibody, clone 7-239 used for the evaluation of CD169 expression on myeloid cell populations by flow cytometry. Mouse anti Human CD169 antibody, clone 7-239 used to block CD169 function on myeliod cells.Image caption:Siglec-1 mediates HIV-1 capture by IFN?-treated myeloid cells. A. Representative profiles of Siglec-1 staining in distinct myeloid cells cultured with or without 1000 U/ml of IFN? and assessed by FACS. Staining of matched-isotype control is also shown. The mean fold increase in fluorescence after IFN&apha; treatment of cells derived from three donors is shown in red numbers. B. Mean number of Siglec-1 antibody binding sites per cell displayed by different myeloid cells exposed to 1000 U/ml of IFN? for 48 h and assessed by quantitative FACS analysis. Data show mean values and SEM from four experiments including cells from 12 donors. C. Comparative binding of HIV-1NL4–3 to different myeloid cells ly exposed to 1000 U/ml of IFN? for 48 h. Cells were cultured with HIV-1NL4–3 for 4 h at 4°C, washed and lysed to measure p24Gag by ELISA. Data show mean values and SEM from two experiments including cells from six donors. D. Relative binding of HIV-1NL4–3 by different IFN?-treated myeloid cells that had been pre-incubated with 10 ug/ml of the indicated mAbs before HIV-1 exposure for 4 h at 4°C as described in C. To compare the effect of the mAbs in different myeloid cells, values were normalized to the level of HIV-1 binding by mock-treated cells (set to 100%). Data show mean values and SEM from two experiments including cells from six donors. Statistical differences were assessed with a paired t test in B and C, and with a one sample t-test in D.From: Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Retrovirology. 2015 May 7;12:37.This image is from an open access article distributed under the terms of the Creative Commons Attribution License.)

Testing Data (PE conjugatedMouse anti Human CD169 antibody, clone 7-239 used to block CD169 function on myeloid cells.Image caption:Siglec-1 mediates HIV-1 uptake into a storage compartment and enhances HIV-1 trans-infection specially in IFN?-treated monocytes and DCs. A. Uptake of HIV-1NL4–3 by different myeloid cells exposed to IFN?. Cells were cultured with HIV-1 to measure p24Gag by ELISA. Mean values and SEM from four experiments include cells from 12 donors. B. Fold change in HIV-1NL4–3 uptake of cells treated with bafilomycin A1 compared to untreated cells. Mean values and SEM include cells from three donors. C. Relative uptake of HIV-1NL4–3 by IFN?-treated myeloid cells pre-incubated with the indicated mAbs. Values are normalized to the level of HIV-1 uptake by mock-treated cells (set at 100%). Mean values and SEM from two experiments include cells from six donors. D. Confocal microscopy analysis of different IFN?-treated myeloid cells pulsed with HIV-1Cherry and stained for Siglec-1 (Alexa 488), HLA-DR (Alexa 647) and DAPI. (Top) Representative viral pattern for each kind of myeloid cell analyzed, showing maximum fluorescence intensity of four channels. (Bottom) Percentage of myeloid cells with distinct viral patterns: random distribution, polarized accumulation, and sac-like compartment formation, as illustrated in the left drawing. Mean values of 50 cells from two different donors are shown. E. HIV-1 transmission from IFN?-treated myeloid cells to a luciferase reporter CD4+ cell line. HIV-1 infection was determined by induced luciferase activity in relative light units (RLUs). Mean values and SEM from four experiments include cells from 12 donors. F. Relative HIV-1 transmission from IFN?-treated myeloid cells pre-incubated with the indicated mAbs. Values are normalized to the level of HIV-1 trans-infected by mock-treated cells. Mean values and SEM from two experiments include cells from six donors. Statistical differences were assessed with a paired t test in A and E, and with a one sample t-test in B, C and F.From: Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Retrovirology. 2015 May 7;12:37.This image is from an open access article distributed under the terms of the Creative Commons Attribution License.)

CD169, Monoclonal Antibody (Cat# AAA225766)

Full Name

Mouse Anti Human CD169: APC

Gene Names

SIGLEC1; SN; CD169; SIGLEC-1

Reactivity

Human

Applications

FC/FACS

Purity

>95% by SDS PAGE
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.

Pricing

$555/100 Tests | $2,340/5x100 Tests

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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded human brain carcinoma, using FoxO1a Antibody(MBS179077)FOXO1 was detected in paraffin-embedded tissue section. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1ug/ml rabbit anti-FOXO1 Antibody (MBS179077)overnight at 4 degree C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37 degree C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen. )

FoxO1a, Monoclonal Antibody (Cat# AAA179077)

Full Name

Anti-FoxO1a Rabbit Monoclonal Antibody

Gene Names

FOXO1; FKH1; FKHR; FOXO1A

Reactivity

Human, Mouse, Rat

Applications

IF, IHC, ICC, WB

Purity

Affinity-chromatography

Pricing

$370/0.1 mL | $1,600/5x0.1 mL

740 Y-P, Inhibitor (Cat# AAA5764260)

Full Name

740 Y-P

Purity

98.00%

Pricing

$240/1 mg | $375/5 mg | $485/10 mg | $720/25 mg | $2,975/5x25 mg

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Western Blot (WB) (Western blot analysis of Smad3 expression in (1) Jurkat cell lysate; (2) Rat liver lysate (MBS179069).Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each lane was loaded with 50ug of sample under reducing conditions. After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-SMAD3 monoclonal antibody overnight at 4 degree C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit with Tanon 5200 system. A specific band was detected for SMAD3 )

Smad3, Monoclonal Antibody (Cat# AAA179069)

Full Name

Anti-Smad3 Rabbit Monoclonal Antibody

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Reactivity

Human, Mouse, Rat

Applications

FC/FACS, IF, IHC, ICC, WB

Purity

Affinity-chromatography

Pricing

$370/0.1 mL | $1,600/5x0.1 mL

SMAD4 / Mothers Against Decapentaplegic Homolog 4, Recombinant Protein (Cat# AAA2903071)

Full Name

Human SMAD4 / Mothers Against Decapentaplegic Homolog 4 Recombinant Protein

Gene Names

SMAD4; JIP; DPC4; MADH4; MYHRS

Applications

EIA, WB, AP

Purity

>95% by SDS-PAGE

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Testing Data (Surface Staining of buffy coat differentiated monocytes by Mouse anti Human CD169:RPE )

Testing Data (PE conjugated Mouse anti CD169 antibody, clone 7-239 used for the evaluation of CD169 expression on myeloid cell populations by flow cytometry. Mouse anti Human CD169 antibody, clone 7-239 used to block CD169 function on myeliod cells.Image caption:Siglec-1 mediates HIV-1 capture by IFN?-treated myeloid cells. A. Representative profiles of Siglec-1 staining in distinct myeloid cells cultured with or without 1000 U/ml of IFN? and assessed by FACS. Staining of matched-isotype control is also shown. The mean fold increase in fluorescence after IFN&apha; treatment of cells derived from three donors is shown in red numbers. B. Mean number of Siglec-1 antibody binding sites per cell displayed by different myeloid cells exposed to 1000 U/ml of IFN? for 48 h and assessed by quantitative FACS analysis. Data show mean values and SEM from four experiments including cells from 12 donors. C. Comparative binding of HIV-1NL4–3 to different myeloid cells ly exposed to 1000 U/ml of IFN? for 48 h. Cells were cultured with HIV-1NL4–3 for 4 h at 4°C, washed and lysed to measure p24Gag by ELISA. Data show mean values and SEM from two experiments including cells from six donors. D. Relative binding of HIV-1NL4–3 by different IFN?-treated myeloid cells that had been pre-incubated with 10 ug/ml of the indicated mAbs before HIV-1 exposure for 4 h at 4°C as described in C. To compare the effect of the mAbs in different myeloid cells, values were normalized to the level of HIV-1 binding by mock-treated cells (set to 100%). Data show mean values and SEM from two experiments including cells from six donors. Statistical differences were assessed with a paired t test in B and C, and with a one sample t-test in D.From: Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Retrovirology. 2015 May 7;12:37.This image is from an open access article distributed under the terms of the Creative Commons Attribution License.)

Testing Data (PE conjugatedMouse anti Human CD169 antibody, clone 7-239 used to block CD169 function on myeloid cells.Image caption:Siglec-1 mediates HIV-1 uptake into a storage compartment and enhances HIV-1 trans-infection specially in IFN?-treated monocytes and DCs. A. Uptake of HIV-1NL4–3 by different myeloid cells exposed to IFN?. Cells were cultured with HIV-1 to measure p24Gag by ELISA. Mean values and SEM from four experiments include cells from 12 donors. B. Fold change in HIV-1NL4–3 uptake of cells treated with bafilomycin A1 compared to untreated cells. Mean values and SEM include cells from three donors. C. Relative uptake of HIV-1NL4–3 by IFN?-treated myeloid cells pre-incubated with the indicated mAbs. Values are normalized to the level of HIV-1 uptake by mock-treated cells (set at 100%). Mean values and SEM from two experiments include cells from six donors. D. Confocal microscopy analysis of different IFN?-treated myeloid cells pulsed with HIV-1Cherry and stained for Siglec-1 (Alexa 488), HLA-DR (Alexa 647) and DAPI. (Top) Representative viral pattern for each kind of myeloid cell analyzed, showing maximum fluorescence intensity of four channels. (Bottom) Percentage of myeloid cells with distinct viral patterns: random distribution, polarized accumulation, and sac-like compartment formation, as illustrated in the left drawing. Mean values of 50 cells from two different donors are shown. E. HIV-1 transmission from IFN?-treated myeloid cells to a luciferase reporter CD4+ cell line. HIV-1 infection was determined by induced luciferase activity in relative light units (RLUs). Mean values and SEM from four experiments include cells from 12 donors. F. Relative HIV-1 transmission from IFN?-treated myeloid cells pre-incubated with the indicated mAbs. Values are normalized to the level of HIV-1 trans-infected by mock-treated cells. Mean values and SEM from two experiments include cells from six donors. Statistical differences were assessed with a paired t test in A and E, and with a one sample t-test in B, C and F.From: Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Retrovirology. 2015 May 7;12:37.This image is from an open access article distributed under the terms of the Creative Commons Attribution License.)

CD169, Monoclonal Antibody (Cat# AAA225768)

Full Name

Mouse Anti Human CD169: RPE

Gene Names

SIGLEC1; SN; CD169; SIGLEC-1

Reactivity

Human

Applications

FC/FACS

Purity

>95% by SDS PAGE
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.

Pricing

$555/100 Tests | $2,340/5x100 Tests

Smad3, Polyclonal Antibody (Cat# AAA9613520)

Full Name

Smad3 Antibody

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (86%)

Applications

IF, ICC, EIA

Purity

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin

Pricing

$260/0.1 mL | $305/0.2 mL | $1,220/5x0.2 mL

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Western Blot (WB) (Western blot analysis of CD66/CEACAM1 (Phospho-Ser508) using LPS treated HeLa whole cell lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

CD66/CEACAM1, Polyclonal Antibody (Cat# AAA9614041)

Full Name

Phospho-CD66/CEACAM1 (Ser508) Antibody

Gene Names

CEACAM1; BGP; BGP1; BGPI

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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SQSTM1/p62, Polyclonal Antibody (Cat# AAA9614520)

Full Name

Phospho-SQSTM1/p62 (Ser28) Antibody

Gene Names

SQSTM1; p60; p62; A170; OSIL; PDB3; ZIP3; p62B

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (83%), Bovine (83%), Rabbit (83%)

Applications

WB, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

Diosgenin glucoside, Inhibitor (Cat# AAA579820)

Full Name

Diosgenin glucoside

Purity

99.0%

Pricing

$175/1 mg | $205/5 mg | $240/10 mg | $810/5x10 mg

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Western Blot (WB) (Western blot analysis Smad3 (Phospho-Ser423) using HepG2 whole cell lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

Smad3, Polyclonal Antibody (Cat# AAA9614448)

Full Name

Phospho-Smad3 (Ser423) Antibody

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Chicken (100%), Xenopus (100%)

Applications

WB, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

DCP1A, Monoclonal Antibody (Cat# AAA1752330)

Full Name

Anti-DCP1A Monoclonal Antibody

Gene Names

DCP1A; SMIF; SMAD4IP1; HSA275986; Nbla00360

Reactivity

Human, Mouse, Rat

Applications

FC/FACS, ICC, IF, IHC, WB

Purity

Affinity-Chromatography

Pricing

$370/0.1 mL | $1,600/5x0.1 mL

TP53 / Cellular Tumor Antigen P53, Recombinant Protein (Cat# AAA2901976)

Full Name

Human TP53 / Cellular Tumor Antigen P53 Recombinant Protein

Gene Names

TP53; P53; BCC7; LFS1; BMFS5; TRP53

Applications

EIA, WB, AP

Purity

>95% by SDS-PAGE

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Smad3, Polyclonal Antibody (Cat# AAA9614316)

Full Name

Phospho-Smad3 (Ser423+Ser425) Antibody

Gene Names

SMAD3; LDS3; LDS1C; MADH3; JV15-2; HSPC193; HsT17436

Reactivity

Human, Mouse, Rat

Applications

WB, IHC, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613238)

Full Name

Phospho-Tuberin/TSC2 (Ser664) Antibody

Gene Names

TSC2; LAM; TSC4

Reactivity

Human
Predicted Reactivity: Pig (100%), Horse (100%)

Applications

WB, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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Western Blot (WB) (Western blot analysis of VASP (Phospho-Thr278) using Mouse brain tissue lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

VASP, Polyclonal Antibody (Cat# AAA9614405)

Full Name

Phospho-VASP (Thr278) Antibody

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%)

Applications

WB, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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Western Blot (WB) (Western blot analysis Smad2 (Phospho-Ser245) using Serum treated LOVO whole cell lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

Smad2, Polyclonal Antibody (Cat# AAA9614061)

Full Name

Phospho-Smad2 (Ser245) Antibody

Gene Names

SMAD2; JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100%)

Applications

WB, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

SMAD2 / Mothers Against Decapentaplegic Homolog 2, Recombinant Protein (Cat# AAA2903226)

Full Name

Human SMAD2 / Mothers Against Decapentaplegic Homolog 2 Recombinant Protein

Gene Names

SMAD2; JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

Applications

EIA, WB, AP

Purity

>95% by SDS-PAGE

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Smad2, Polyclonal Antibody (Cat# AAA9614315)

Full Name

Phospho-Smad2 (Ser465+Ser467) Antibody

Gene Names

SMAD2; JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (100%)

Applications

WB, IHC, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

Pteropodine, Inhibitor (Cat# AAA5760829)

Full Name

Pteropodine

Purity

98.00%

Pricing

$390/1 mg | $1,475/5x1 mg

ITCH, Polyclonal Antibody (Cat# AAA9613128)

Full Name

Phospho-ITCH (Tyr420) Antibody

Gene Names

ITCH; AIF4; AIP4; NAPP1; dJ468O1.1

Reactivity

Human, Mouse
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (91%)

Applications

WB, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

CD28, Monoclonal Antibody (Cat# AAA3014184)

Full Name

Human CD28 (3G5E) Monoclonal Antibody

Gene Names

CD28; Tp44

Reactivity

Human

Applications

FC/FACS, IHC, IP

Purity

Protein A purified mouse monoclonal antibody, >95% immunoglobulin by SDS-PAGE

Pricing

$275/0.05 mL | $365/0.1 mL | $1,375/5x0.1 mL

IL10, Active Protein (Cat# AAA4159767)

Full Name

Recombinant Human IL10

Gene Names

IL10; CSIF; TGIF; GVHDS; IL-10; IL10A

Purity

>95% as determined by SDS-PAGE

Pricing

$310/0.01 mg | $5,850/1 mg

14-3-3 epsilon, Recombinant Protein (Cat# AAA8120516)

Full Name

14-3-3 epsilon Protein, Human, Recombinant

Gene Names

YWHAE; MDS; MDCR; KCIP-1; 14-3-3E

Purity

>96% as determined by SDS-PAGE

Pricing

$450/0.1 mg | $1,885/5x0.1 mg

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Western Blot (WB) (Western blot analysis of TSC2 (Phospho-Ser1254) using COLO205 whole cell lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9614355)

Full Name

Phospho-Tuberin/TSC2 (Ser1254) Antibody

Gene Names

TSC2; LAM; TSC4

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%)

Applications

WB, IHC, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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<< Previous Next >>

Western Blot (WB) (Western blot analysis Smad2 (Phospho-Ser255) using heatshock treated HT29 whole cell lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

Smad2, Polyclonal Antibody (Cat# AAA9614060)

Full Name

Phospho-Smad2 (Ser255) Antibody

Gene Names

SMAD2; JV18; MADH2; MADR2; JV18-1; hMAD-2; hSMAD2

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Zebrafish (89%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%), Xenopus (89%)

Applications

WB, IHC, IF, ICC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613444)

Full Name

Tuberin/TSC2 Antibody

Gene Names

TSC2; LAM; TSC4

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Zebrafish (100%), Bovine (100%), Horse (100%), Sheep (100%)

Applications

WB, EIA

Purity

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin

Pricing

$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL

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Testing Data (Surface Staining of buffy coat differentiated monocytes by Mouse anti Human CD169:RPE )

Testing Data (PE conjugated Mouse anti CD169 antibody, clone 7-239 used for the evaluation of CD169 expression on myeloid cell populations by flow cytometry. Mouse anti Human CD169 antibody, clone 7-239 used to block CD169 function on myeliod cells.Image caption:Siglec-1 mediates HIV-1 capture by IFN?-treated myeloid cells. A. Representative profiles of Siglec-1 staining in distinct myeloid cells cultured with or without 1000 U/ml of IFN? and assessed by FACS. Staining of matched-isotype control is also shown. The mean fold increase in fluorescence after IFN&apha; treatment of cells derived from three donors is shown in red numbers. B. Mean number of Siglec-1 antibody binding sites per cell displayed by different myeloid cells exposed to 1000 U/ml of IFN? for 48 h and assessed by quantitative FACS analysis. Data show mean values and SEM from four experiments including cells from 12 donors. C. Comparative binding of HIV-1NL4–3 to different myeloid cells ly exposed to 1000 U/ml of IFN? for 48 h. Cells were cultured with HIV-1NL4–3 for 4 h at 4°C, washed and lysed to measure p24Gag by ELISA. Data show mean values and SEM from two experiments including cells from six donors. D. Relative binding of HIV-1NL4–3 by different IFN?-treated myeloid cells that had been pre-incubated with 10 ug/ml of the indicated mAbs before HIV-1 exposure for 4 h at 4°C as described in C. To compare the effect of the mAbs in different myeloid cells, values were normalized to the level of HIV-1 binding by mock-treated cells (set to 100%). Data show mean values and SEM from two experiments including cells from six donors. Statistical differences were assessed with a paired t test in B and C, and with a one sample t-test in D.From: Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Retrovirology. 2015 May 7;12:37.This image is from an open access article distributed under the terms of the Creative Commons Attribution License.)

Testing Data (PE conjugatedMouse anti Human CD169 antibody, clone 7-239 used to block CD169 function on myeloid cells.Image caption:Siglec-1 mediates HIV-1 uptake into a storage compartment and enhances HIV-1 trans-infection specially in IFN?-treated monocytes and DCs. A. Uptake of HIV-1NL4–3 by different myeloid cells exposed to IFN?. Cells were cultured with HIV-1 to measure p24Gag by ELISA. Mean values and SEM from four experiments include cells from 12 donors. B. Fold change in HIV-1NL4–3 uptake of cells treated with bafilomycin A1 compared to untreated cells. Mean values and SEM include cells from three donors. C. Relative uptake of HIV-1NL4–3 by IFN?-treated myeloid cells pre-incubated with the indicated mAbs. Values are normalized to the level of HIV-1 uptake by mock-treated cells (set at 100%). Mean values and SEM from two experiments include cells from six donors. D. Confocal microscopy analysis of different IFN?-treated myeloid cells pulsed with HIV-1Cherry and stained for Siglec-1 (Alexa 488), HLA-DR (Alexa 647) and DAPI. (Top) Representative viral pattern for each kind of myeloid cell analyzed, showing maximum fluorescence intensity of four channels. (Bottom) Percentage of myeloid cells with distinct viral patterns: random distribution, polarized accumulation, and sac-like compartment formation, as illustrated in the left drawing. Mean values of 50 cells from two different donors are shown. E. HIV-1 transmission from IFN?-treated myeloid cells to a luciferase reporter CD4+ cell line. HIV-1 infection was determined by induced luciferase activity in relative light units (RLUs). Mean values and SEM from four experiments include cells from 12 donors. F. Relative HIV-1 transmission from IFN?-treated myeloid cells pre-incubated with the indicated mAbs. Values are normalized to the level of HIV-1 trans-infected by mock-treated cells. Mean values and SEM from two experiments include cells from six donors. Statistical differences were assessed with a paired t test in A and E, and with a one sample t-test in B, C and F.From: Pino M, Erkizia I, Benet S, Erikson E, Fernández-Figueras MT, Guerrero D, Dalmau J, Ouchi D, Rausell A, Ciuffi A, Keppler OT, Telenti A, Kräusslich HG, Martinez-Picado J, Izquierdo-Useros N.HIV-1 immune activation induces Siglec-1 expression and enhances viral trans-infection in blood and tissue myeloid cells.Retrovirology. 2015 May 7;12:37.This image is from an open access article distributed under the terms of the Creative Commons Attribution License.)

CD169, Monoclonal Antibody (Cat# AAA225767)

Full Name

Mouse Anti Human CD169

Gene Names

SIGLEC1; SN; CD169; SIGLEC-1

Reactivity

Human

Applications

IHC, FC/FACS, FN, IP, WB

Purity

>95% by SDS PAGE
Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant.

Pricing

$380/0.1 mg | $1,565/5x0.1 mg

XL041, Inhibitor (Cat# AAA5754629)

Full Name

XL041

Purity

98.00%

Pricing

$240/1 mg | $405/5 mg | $560/10 mg | $1,400/50 mg | $1,910/100 mg | $505/1mL*10mM (in DMSO) | $8,300/5x100 mg

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613239)

Full Name

Phospho-Tuberin/TSC2 (Tyr1571) Antibody

Gene Names

TSC2; LAM; TSC4

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Sheep (100%)

Applications

WB, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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Testing Data (Figure A. RPE conjugated Mouse anti Bovine CD335 and FITC conjugated Mouse IgG2b isotype control . Figure B. RPE conjugated Mouse anti Bovine CD335 and FITC conjugated Mouse anti Bovine CD11b . All experiments performed on red cell lysed bovine blood gated on live cells in the presence of 10% bovine serum. Data acquired on the ZE5 Cell Analyzer.)

CD11b, Monoclonal Antibody (Cat# AAA225942)

Full Name

MOUSE ANTI BOVINE CD11b: RPE

Reactivity

Bovine

Applications

FC/FACS

Pricing

$710/100 Tests | $3,035/5x100 Tests

ITCH, Polyclonal Antibody (Cat# AAA9613335)

Full Name

ITCH Antibody

Gene Names

ITCH; AIF4; AIP4; NAPP1; dJ468O1.1

Reactivity

Human, Mouse
Predicted Reactivity: Pig (100%), Bovine (100%), Horse (100%), Rabbit (100%), Dog (100%), Chicken (91%)

Applications

WB, EIA

Purity

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin

Pricing

$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL

14-3-3 epsilon, Recombinant Protein (Cat# AAA8120515)

Full Name

14-3-3 epsilon Protein, Human, Recombinant (GST Tag)

Gene Names

YWHAE; MDS; MDCR; KCIP-1; 14-3-3E

Purity

>92% as determined by SDS-PAGE

Pricing

$450/0.1 mg | $1,885/5x0.1 mg

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Western Blot (WB) (Western blot analysis of CD66 (Phospho-Ser508) using Calc LOVO whole cell lysates.-/+ means absence or presence of N peptideï¼ˆnon-phospho peptide) and P peptide(phospho peptide).)

CD66/CEACAM1, Polyclonal Antibody (Cat# AAA9614412)

Full Name

Phospho-CD66/CEACAM1 (Ser508) Antibody

Gene Names

CEACAM1; BGP; BGP1; BGPI

Reactivity

Human

Applications

WB, IHC, EIA

Purity

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Pricing

$245/0.05 mL | $310/0.1 mL | $370/0.2 mL | $1,605/5x0.2 mL

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Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613445)

Full Name

Tuberin/TSC2 Antibody

Gene Names

TSC2; LAM; TSC4

Reactivity

Human, Mouse, Rat
Predicted Reactivity: Pig (100%), Horse (100%)

Applications

WB, EIA

Purity

The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin

Pricing

$245/0.05 mL | $305/0.1 mL | $365/0.2 mL | $1,495/5x0.2 mL

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Type

Reactivity

Gene Name

Isotype

Host

Application

Clone

165 results for " Co stimulation" - showing 100-150

HOP, Recombinant Protein (Cat# AAA806900)

p23, Recombinant Protein (Cat# AAA806950)

SMAD3, Blocking Peptide (Cat# AAA9219988)

IL10, Active Protein (Cat# AAA5304240)

PTRF, Blocking Peptide (Cat# AAA9226877)

PTRF, Blocking Peptide (Cat# AAA9226878)

SMAD3 (S213), Blocking Peptide (Cat# AAA9225068)

Smad3, Blocking Peptide (Cat# AAA9229835)

IL10, Active Protein (Cat# AAA5304114)

SMAD3, Blocking Peptide (Cat# AAA9229783)

Smad3, Blocking Peptide (Cat# AAA9229870)

IL7, Active Protein (Cat# AAA5304042)

SMAD3-S208, Blocking Peptide (Cat# AAA9228529)

SMAD3 (S208), Blocking Peptide (Cat# AAA9225067)

IL18, Active Protein (Cat# AAA5308747)

CD169, Monoclonal Antibody (Cat# AAA225766)

FoxO1a, Monoclonal Antibody (Cat# AAA179077)

740 Y-P, Inhibitor (Cat# AAA5764260)

Smad3, Monoclonal Antibody (Cat# AAA179069)

SMAD4 / Mothers Against Decapentaplegic Homolog 4, Recombinant Protein (Cat# AAA2903071)

CD169, Monoclonal Antibody (Cat# AAA225768)

Smad3, Polyclonal Antibody (Cat# AAA9613520)

CD66/CEACAM1, Polyclonal Antibody (Cat# AAA9614041)

SQSTM1/p62, Polyclonal Antibody (Cat# AAA9614520)

Diosgenin glucoside, Inhibitor (Cat# AAA579820)

Smad3, Polyclonal Antibody (Cat# AAA9614448)

DCP1A, Monoclonal Antibody (Cat# AAA1752330)

TP53 / Cellular Tumor Antigen P53, Recombinant Protein (Cat# AAA2901976)

Smad3, Polyclonal Antibody (Cat# AAA9614316)

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613238)

VASP, Polyclonal Antibody (Cat# AAA9614405)

Smad2, Polyclonal Antibody (Cat# AAA9614061)

SMAD2 / Mothers Against Decapentaplegic Homolog 2, Recombinant Protein (Cat# AAA2903226)

Smad2, Polyclonal Antibody (Cat# AAA9614315)

Pteropodine, Inhibitor (Cat# AAA5760829)

ITCH, Polyclonal Antibody (Cat# AAA9613128)

CD28, Monoclonal Antibody (Cat# AAA3014184)

IL10, Active Protein (Cat# AAA4159767)

14-3-3 epsilon, Recombinant Protein (Cat# AAA8120516)

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9614355)

Smad2, Polyclonal Antibody (Cat# AAA9614060)

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613444)

CD169, Monoclonal Antibody (Cat# AAA225767)

XL041, Inhibitor (Cat# AAA5754629)

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613239)

CD11b, Monoclonal Antibody (Cat# AAA225942)

ITCH, Polyclonal Antibody (Cat# AAA9613335)

14-3-3 epsilon, Recombinant Protein (Cat# AAA8120515)

CD66/CEACAM1, Polyclonal Antibody (Cat# AAA9614412)

Tuberin/TSC2, Polyclonal Antibody (Cat# AAA9613445)

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