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153 results for " Caspase Inhibitors" - showing 1-50
Testing Data
(Published customer image: Confirmation and in vitro characterization of Hit compounds. A) HeLa cells were treated with the ten compounds that produced the strongest reduction in pSer40/41MCM2 levels in the primary screen. Protein extracts were prepared and levels of residual pSer40/41MCM2 phosphorylation were measured by western blot analysis with the indicated antibodies. B) The same compounds were tested for their ability to inhibit CDC7 kinase activity in in vitro kinase assay. Kinase reactions were performed on a synthetic MCM2 substrate in the absence or presence of the indicated drug and reactions were run on SDS-PAGE gels. CDC7 activity on the synthetic MCM2 substrate was monitored by Western blotting with an anti-pSer108MCM2 antibody. As a control the levels of CDC7 kinase and synthetic MCM2 substrate present in each reaction were also assessed and shown to be similar in all reactions.From: FitzGerald J, Murillo LS, O'Brien G, O'Connell E, O'Connor A, et al. (2014) A High Through-Put Screen for Small Molecules Modulating MCM2 Phosphorylation Identifies Ryuvidine as an Inducer of the DNA Damage Response. PLoS ONE 9(6): e98891.)
MCM2, Monoclonal Antibody (Cat# AAA212357)
Full Name
MOUSE ANTI HUMAN MCM2
Gene Names
MCM2; BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN
Applications
WB
Pricing
$345/0.1 mg | $1,405/5x0.1 mg
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed A431, using BCL2L10 antibody at 1:200 dilution.)
BclB, Polyclonal Antibody (Cat# AAA837676)
Full Name
BclB antibody
Gene Names
BCL2L10; Boo; Diva; BCL-B; bcl2-L-10
Applications
IF, ICC, IHC, WB
Purity
BclB antibody was purified by antigen-affinity chromatography
Pricing
$700/0.1 mL | $3,130/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using caspase-4 antibody at 1:200 dilution.)
Caspase 4, Polyclonal Antibody (Cat# AAA5311751)
Full Name
Caspase 4 Antibody
Gene Names
Casp4; Casp11
Applications
IF, ICC, IHC, WB
Purity
Antigen-Affinity Chromatography
Pricing
$700/0.1 mL | $3,130/5x0.1 mL
Immunofluorescence (IF)
(Immunofluorescence analysis of methanol-fixed HeLa, using Caspase 8 antibody at 1:200 dilution.)
Caspase 8, Polyclonal Antibody (Cat# AAA5311790)
Full Name
Caspase 8 Antibody
Gene Names
CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Applications
IF, ICC, IHC, WB
Purity
Antigen-Affinity Chromatography
Pricing
$700/0.1 mL | $3,130/5x0.1 mL
Granzyme B, Active Protein (Cat# AAA539538)
Full Name
Granzyme B protein
Applications
User optimized
Purity
> 98% pure
Pricing
$425/0.01 mg | $1,905/5x0.01 mg
Western Blot (WB)
(Western Blot Analysis of Dio-1 expression with Jurkat Cell Lysate.)
DIO1, Polyclonal Antibody (Cat# AAA835559)
Full Name
DIO1 antibody
Applications
WB
Purity
DIO1 antibody was purified by affinity chromatography
Pricing
$460/0.1 mg | $2,070/5x0.1 mg
Caspase 3, rat, active, Active Protein (Cat# AAA636907)
Full Name
Caspase 3, Recombinant, rat, active (CPP-32, Apoptain, Yama, SCA-1)
Purity
Purified
80% (SDS-PAGE)
80% (SDS-PAGE)
Pricing
$435/25 Units | $655/100 Units | $2,935/5x100 Units
Caspase 8, active, Active Protein (Cat# AAA635529)
Full Name
Caspase 8 (FLICE, MASH, Mch5), Active, Recombinant, His-tagged, Human
Gene Names
CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Applications
Suitable for use in Screening for caspase inhibitors, Studying enzyme regulation, Determining target substrates, and as Positive control in caspase activity assays. Other applications not tested.
Purity
> or = 95% by SDS-PAGE
Pricing
$525/25 Units | $745/100 Units | $3,345/5x100 Units
Western Blot (WB)
(Western blot analysis of caspase-8 expression in mouse intestine and rat kidney tissue lysate)
Active Caspase 8, Polyclonal Antibody (Cat# AAA837619)
Full Name
Active Caspase 8 antibody
Applications
WB
Purity
Active Caspase 8 antibody was purified by affinity chromatography
Pricing
$495/0.1 mg | $2,215/5x0.1 mg
Caspase 1, Active, Active Protein (Cat# AAA635822)
Full Name
Caspase 1, Active, Recombinant, Human
Gene Names
CASP1; ICE; P45; IL1BC
Applications
WB
Purity
Molecular Biology Grade
Pricing
$525/25 Units | $745/100 Units | $3,345/5x100 Units
Western Blot (WB)
(Western blot analysis of D4-GDI with Jurkat cell lysate.)
D4GDI, Polyclonal Antibody (Cat# AAA837331)
Full Name
D4GDI antibody
Applications
WB
Purity
D4GDI antibody was purified by affinity chromatography
Pricing
$495/0.1 mg | $2,225/5x0.1 mg
Western Blot (WB)
(Western blot analysis of cIAP-2 in Jurkat cell lysates.)
cIAP2, Polyclonal Antibody (Cat# AAA837655)
Full Name
cIAP2 antibody
Applications
WB
Purity
cIAP2 antibody was purified by affinity chromatography
Pricing
$460/0.1 mg | $2,070/5x0.1 mg
Western Blot (WB)
(Western blot analysis of cIAP-1 inmouse small intestine tissue lysate.)
cIAP1, Polyclonal Antibody (Cat# AAA835448)
Full Name
cIAP1 antibody
Applications
WB
Purity
cIAP1 antibody was purified by affinity chromatography
Pricing
$460/0.1 mg | $2,070/5x0.1 mg
Caspase 3, Recombinant Protein (Cat# AAA5303832)
Full Name
Caspase 3 protein
Gene Names
Casp3; caspase-3
Purity
Caspase 3 protein was purified using a a proprietary chromatographic technique.
Pricing
$540/100 Units | $2,425/5x100 Units
flip (I-flICE) (flICE Inhibitory Protein), Polyclonal Antibody (Cat# AAA395625)
Full Name
flip (NT) (I-flICE) (flICE Inhibitory Protein)
Gene Names
Casp8ap2; FLASH; AA387232; mKIAA1315; D4Ertd659e
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Antigen Immunoaffiinity Purification
Pricing
$610/0.1 mg | $2,585/5x0.1 mg
Caspase 3, Recombinant Protein (Cat# AAA5304184)
Full Name
Caspase 3 protein
Gene Names
Casp3; caspase-3
Purity
Caspase 3 protein was purified using a a proprietary chromatographic technique.
Pricing
$550/100 Units | $2,465/5x100 Units
Caspase 3, Recombinant Protein (Cat# AAA5304552)
Full Name
Caspase 3 protein
Gene Names
Casp3; caspase-3
Purity
Caspase 3 protein was purified using a a proprietary chromatographic technique.
Pricing
$525/100 Units | $2,350/5x100 Units
Western Blot (WB)
(Western blot analysis of recombinant PI9. Lane 1: 2 ug. Lane 2: 5 ug. Lane 3: 10 ug.)
PI9, Monoclonal Antibody (Cat# AAA833224)
Full Name
PI9 antibody
Applications
WB
Purity
PI9 antibody was purified by affinity chromatography
Pricing
$540/0.1 mg | $2,425/5x0.1 mg
Western Blot (WB)
(Western blot analysis of cIAP-1 in Jurkat cell lysates.)
cIAP1, Polyclonal Antibody (Cat# AAA835144)
Full Name
cIAP1 antibody
Applications
WB
Purity
cIAP1 antibody was purified by affinity chromatography
Pricing
$515/0.1 mg | $2,315/5x0.1 mg
Caspase 3, active, Active Protein (Cat# AAA636958)
Full Name
Caspase 3, active, Recombinant, Human (CPP-32, Apoptain, Yama, SCA-1)
Gene Names
CASP3; CPP32; SCA-1; CPP32B
Purity
Molecular Biology Grade
Pricing
$430/25 Units | $665/100 Units | $2,980/5x100 Units
Testing Data #1
(Western blot analysis of whole cell lysates from HepG2 (1) and MOLT4 (2) cells probed with Rabbit anti ILP-2 (MBS221700))
ILP-2, Polyclonal Antibody (Cat# AAA221700)
Full Name
RABBIT ANTI ILP-2
Gene Names
BIRC8; ILP2; ILP-2; hILP2
Reactivity
Mouse (Expected from Sequence), Rat (Expected from Sequence)
Applications
WB
Pricing
$340/0.1 mg | $1,375/5x0.1 mg
Western Blot (WB)
(Western blot analysis of Jurkat cells induced with 2mM of Camptothecin for 6 hours.)
Active Caspase 7, Polyclonal Antibody (Cat# AAA835766)
Full Name
Active Caspase 7 antibody
Reactivity
Human, Mouse, Rat
Applications
WB, IP, IHC
Purity
Active Caspase 7 antibody was purified by affinity chromatography
ROCK 1, Monoclonal Antibody (Cat# AAA834700)
Full Name
ROCK 1 antibody
Applications
WB
Purity
ROCK 1 antibody was purified by Protein G purification.
Western Blot (WB)
(Western blot analysis of caspase-4 in 293 cell lysate.)
Caspase 4, Monoclonal Antibody (Cat# AAA834407)
Full Name
Caspase 4 antibody
Gene Names
Casp4; Casp11
Reactivity
Human
Applications
WB
Purity
Caspase 4 antibody was purified by affinity chromatography
Western Blot (WB)
(Western blot analysis of caspase 11 with 3T3 cell lysate.)
Caspase 11, Polyclonal Antibody (Cat# AAA835150)
Full Name
Caspase 11 antibody
Applications
WB
Purity
Caspase 11 antibody was purified by affinity chromatography
Pricing
$510/0.1 mg | $2,275/5x0.1 mg
Western Blot (WB)
(Western blot analysis with Jurkat cell lysate. Lane 1: Untreated;Lane 2: Etoposide treated.)
Active Caspase 9, Polyclonal Antibody (Cat# AAA837333)
Full Name
Active Caspase 9 antibody
Applications
IP, WB
Purity
Active Caspase 9 antibody was purified by affinity chromatography
Pricing
$715/0.1 mg | $3,220/5x0.1 mg
DNAPK, Polyclonal Antibody (Cat# AAA835208)
Full Name
DNAPK antibody
Applications
WB
Purity
DNAPK antibody was purified by affinity chromatography
Pricing
$495/0.1 mg | $2,225/5x0.1 mg
Western Blot/Blotting
(Western blot analysis)
flip (I-flICE) (flICE Inhibitory Protein), Polyclonal Antibody (Cat# AAA395728)
Full Name
flip (IN) (I-flICE) (flICE Inhibitory Protein)
Gene Names
Casp8ap2; FLASH; AA387232; mKIAA1315; D4Ertd659e
Reactivity
Human, Mouse, Rat
Applications
WB
Purity
Antigen Immunoaffiinity Purification
Pricing
$610/0.1 mg | $2,585/5x0.1 mg
Western Blot (WB)
(Western blot analysis of TUCAN expression in mouse small intestine tissue lysate.)
TUCAN, Polyclonal Antibody (Cat# AAA837445)
Full Name
TUCAN antibody
Applications
WB
Purity
TUCAN antibody was purified by affinity chromatography
Pricing
$460/0.1 mg | $2,070/5x0.1 mg
Western Blot (WB)
(Western Blot showing PAK2 antibody used against Hela (1), Jurkat (2), A549 (3), HEK293 (4) and K562 (5) cell lysate.)
PAK2, Monoclonal Antibody (Cat# AAA831890)
Full Name
PAK2 antibody
Applications
EIA, IF, IHC, WB
Pricing
$675/0.1 mL | $3,035/5x0.1 mL
Caspase 5, Active, Active Protein (Cat# AAA636827)
Full Name
Caspase 5, Active, Recombinant, Human (Ich-3, ICErel-III, TY)
Gene Names
CASP5; ICH-3; ICEREL-III; ICE(rel)III
Purity
Molecular Biology Grade
Pricing
$500/25 Units | $725/100 Units | $3,250/5x100 Units
PI9, Polyclonal Antibody (Cat# AAA835645)
Full Name
PI9 antibody
Applications
WB
Purity
PI9 antibody was purified by affinity chromatography
Pricing
$460/0.1 mg | $2,070/5x0.1 mg
Caspase 2 Inhibitor, Cell Culture, VDVAD-FMK, 2mM, Inhibitor (Cat# AAA655466)
Full Name
Caspase 2 Inhibitor, Cell Culture, VDVAD-FMK, 2mM (ICH1, Nedd2)
Purity
Highly Purified
98% by HPLC analysis
98% by HPLC analysis
Pricing
$410/0.1 mL | $1,845/5x0.1 mL
Caspase 1, Recombinant Protein (Cat# AAA5304550)
Full Name
Caspase 1 protein
Gene Names
Casp1; Ice; Il1bc
Purity
Caspase 1 protein was purified using a a proprietary chromatographic technique.
Pricing
$380/25 Units | $1,695/5x25 Units
AKT2, Polyclonal Antibody (Cat# AAA1489636)
Full Name
Rabbit Anti Human AKT2 PolyClonal Antibody
Gene Names
AKT2; PKBB; PRKBB; HIHGHH; PKBBETA; RAC-BETA
Reactivity
Human, Mouse, Rat
Applications
WB, IHC
Purity
Affinity Purification
Pricing
$325/0.1 mL | $1,465/5x0.1 mL
Caspase 4, Active, Active Protein (Cat# AAA635796)
Full Name
Caspase 4, Active, Recombinant, Human (ICErelII, TX, Ich-2)
Gene Names
CASP10; MCH4; ALPS2; FLICE2
Purity
Molecular Biology Grade
Pricing
$510/25 Units | $745/100 Units | $3,345/5x100 Units
Caspase 7, active, Active Protein (Cat# AAA637680)
Full Name
Caspase 7, active, Recombinant, Human (Mch-3, ICE-LAP3, CMH-1)
Applications
WB
Purity
Molecular Biology Grade
90% by SDS-PAGE
90% by SDS-PAGE
Pricing
$510/25 Units | $745/100 Units | $3,345/5x100 Units
Western Blot (WB)
(Western blot analysis of Separase (pS801) expression in MDA-MB-231 (A); A431 (B) whole cell lysates.)
Separase, Antibody (Cat# AAA5316304)
Full Name
Separase Antibody
Gene Names
ESP; AESP; EXTRA SPINDLE POLES; F7H19.150; F7H19_150; homolog of separase; RADIALLY SWOLLEN 4; RSW4; SEPARASE
Applications
WB, IHC, IF, ICC
Purity
Immunogen Affinity Chromatography
Pricing
$395/0.1 mL | $1,765/5x0.1 mL
Caspase 8, Recombinant Protein (Cat# AAA5304364)
Full Name
Caspase 8 protein
Gene Names
CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Purity
Caspase 8 protein was purified using a a proprietary chromatographic technique.
Pricing
$660/100 Units | $2,960/5x100 Units
Caspase 10 Inhibitor, Cell Culture, 2mM, Z-AEVD-FMK, Inhibitor (Cat# AAA655333)
Full Name
Caspase 10 Inhibitor, Cell Culture, 2mM, Z-AEVD-FMK (FLICE2, Mch4)
Purity
Highly Purified
95% by HPLC analysis
95% by HPLC analysis
Pricing
$410/0.1 mL | $1,845/5x0.1 mL
Active Caspase 6, Polyclonal Antibody (Cat# AAA837446)
Full Name
Active Caspase 6 antibody
Applications
WB
Purity
Active Caspase 6 antibody was purified by affinity chromatography
Pricing
$615/0.1 mg | $2,760/5x0.1 mg
(Asp-Glu-Val-Asp) 2-Rh110, Substrate (Cat# AAA407433)
Full Name
(Asp-Glu-Val-Asp) 2-Rh110
Pricing
$135/1 mg | $215/5 mg | $545/5x1 mg | $915/5x5 mg
Caspase 4, Recombinant Protein (Cat# AAA5303965)
Full Name
Caspase 4 protein
Gene Names
Casp4; Casp11
Purity
Caspase 4 protein was purified using a a proprietary chromatographic technique.
Pricing
$660/100 Units | $2,960/5x100 Units
Western Blot (WB)
()
ICAD, Recombinant Protein (Cat# AAA5304407)
Full Name
ICAD protein
Applications
WB
Purity
> 95% pure
ROCK1, Monoclonal Antibody (Cat# AAA838057)
Full Name
ROCK1 antibody
Applications
WB
Purity
ROCK1 antibody was purified by affinity chromatography
Pricing
$540/0.1 mg | $2,425/5x0.1 mg
Caspase 10 beta, Recombinant Protein (Cat# AAA5304125)
Full Name
Caspase 10 beta protein
Purity
Caspase 10 beta protein was purified using a a proprietary chromatographic technique.
Pricing
$625/100 Units | $2,795/5x100 Units
Caspase 8, Recombinant Protein (Cat# AAA5303999)
Full Name
Caspase 8 protein
Gene Names
CASP8; CAP4; MACH; MCH5; FLICE; ALPS2B; Casp-8
Purity
Caspase 8 protein was purified using a a proprietary chromatographic technique.
Pricing
$525/100 Units | $2,350/5x100 Units
Caspase 6, Recombinant Protein (Cat# AAA5304638)
Full Name
Caspase 6 protein
Purity
Caspase 6 protein was purified using a a proprietary chromatographic technique.
Pricing
$660/100 Units | $2,960/5x100 Units
NLRP2, Polyclonal Antibody (Cat# AAA5303503)
Full Name
NLRP2 antibody
Applications
EIA, IHC
Purity
NLRP2 antibody was purified by Antigen Affinity chromatography
Pricing
$400/0.05 mL | $1,780/5x0.05 mL
Caspase 5, Recombinant Protein (Cat# AAA5304456)
Full Name
Caspase 5 protein
Purity
Caspase 5 protein was purified using a a proprietary chromatographic technique.
Pricing
$630/100 Units | $2,835/5x100 Units
