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8 results for " ACTOne GPCR Stable Cell Lines" - showing 1-8


Testing Data

Delta-type opioid receptor (OPRD1), Cell Line (Cat# AAA430278)

Full Name
Human Delta-type opioid receptor (OPRD1) ACTOne Stable Cell Line
Gene Names
OPRD1; DOP; DOR; DOR1; OPRD
Testing Data

G-protein coupled receptor 119 (GPR119), Cell Line (Cat# AAA430275)

Full Name
Human G protein-coupled receptor 119 (GPR119) ACTOne Stable Cell Line
Gene Names
GPR119; GPCR2
Testing Data

5-Hydroxytryptamine (Serotonin) Receptor 1F (HTR1F), Cell Line (Cat# AAA430277)

Full Name
Human 5-hydroxytryptamine (serotonin) receptor 1F (HTR1F) ACTOne Stable Cell Line
Gene Names
HTR1F; 5HT6; MR77; 5-HT1F; HTR1EL; 5-HT-1F
Testing Data

5-Hydroxytryptamine (Serotonin) Receptor 1A (HTR1A), Cell Line (Cat# AAA430276)

Full Name
Human 5-hydroxytryptamine (serotonin) receptor 1A (HTR1A) ACTOne Stable Cell Line
Gene Names
HTR1A; G-21; 5HT1a; PFMCD; 5-HT1A; 5-HT-1A; ADRBRL1; ADRB2RL1
Testing Data (Figure 1. Response of ACTOne GPBAR1 (TGR5) cell line & parental cell line to LCA. ACTOne GPBAR1 cells and parental cells were plated overnight in 20 ul culture medium on a BD Biocoat 384 well plate. The next day, cells were dye-loaded with 20 ul/well of 1X Dye-loading solution (Membrane Potential Assay Kit). After 2 hours of incubation at room temperature, two readings were obtained prior to and 30 min after the addition of LCA. Ratios of the two readings (F/F0) are plotted in the figure. A. Dose response curve of LCA in ACTOne TGR5 cell line. EC50 = 3.2 uM in the presence of PDE inhibitor. B. Parental cells do not respond to LCA)

G-protein coupled bile acid receptor 1 (GPBAR1), Cell Line (Cat# AAA430274)

Full Name
Human G-protein-coupled bile acid receptor 1 (GPBAR1) ACTOne Stable Cell Line
Gene Names
GPBAR1; BG37; TGR5; M-BAR; GPCR19; GPR131
Testing Data

Sphingosine-1-Phosphate Receptor 5 (S1PR5), Cell Line (Cat# AAA430593)

Full Name
Sphingosine-1-Phosphate Receptor 5 (S1PR5) ACTOne Stable Cell Line, HEK293
Gene Names
S1PR5; EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
Testing Data

Sphingosine-1-Phosphate Receptor 3 (S1PR3), Cell Line (Cat# AAA430592)

Full Name
Sphingosine-1-Phosphate Receptor 3 (S1PR3) ACTOne Stable Cell Line, HEK293
Gene Names
S1PR3; EDG3; LPB3; S1P3; EDG-3
Testing Data (Figure 1. Response of ACTOneTM S1PR2 cell line & parental cell line to S1PACTOneTM S1PR2 cells and parental cells were plated overnight in 20 ul culture mediumon a 384 well Bi degree Coat plate. The next day, cells were dye-loaded with 20 ul/well of 1x Dye-loading solution(membrane potential dye kit). After 2 hours of incubation at room temperature, two readingswere obtained prior to and 30 min after the addition of S1P. Ratios of the two readings (F/F0) are plotted inthe figure.A. Dose response curve of S1P in ACTOneTM S1PR2 cell line. EC50 = 152 nM in the presence ofPDE inhibitor Ro 20-1724 and ?–adren degree Ceptor agonist isoproterenol.B. Parental cells do not respond to S1P.)

Sphingosine-1-Phosphate Receptor 2 (S1PR2), Cell Line (Cat# AAA430591)

Full Name
Sphingosine-1-Phosphate Receptor 2 (S1PR2) ACTOne Stable Cell Line, HEK293
Gene Names
S1PR2; EDG5; H218; LPB2; S1P2; AGR16; EDG-5; Gpcr13
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