MSLN protein
Human MSLN (296-580) Protein, mFc-His Tag
Purity
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Synonyms
MSLN; Human MSLN (296-580) Protein; mFc-His Tag; Mesothelin; MPF; MSLN protein
Host
HEK293 cells
Purity/Purification
The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Form/Format
Lyophilized from sterile PBS, pH 7.4. Normally 5 %-38 % trehalose is added as protectants before lyophilization.
Sequence Positions
MSLN (Glu296-Gly580)+mFc (Pro99-Lys330)
Species
Human
Vector and Tag
C-Mouse Fc and 6xHis tag
Preparation and Storage
Store at -80 degree C for 12 months (Avoid repeated freezing and thawing)
SDS-Page
(Figure 1. Human Mesothelin (296-580) Protein, mFc-His Tag on SDS-PAGE under reducing condition.)
Related Product Information for MSLN protein
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
