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Western Blot (WB) (Western blot analysis of PPAPDC3 in mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 ug/mL.)

Rabbit PPAPDC3 Polyclonal Antibody | anti-PPAPDC3 antibody

PPAPDC3 Antibody

Gene Names
PPAPDC3; NET39; C9orf67
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
PPAPDC3; Polyclonal Antibody; PPAPDC3 Antibody; Phosphatidic acid phosphatase type 2 domain containing 3; NET39; anti-PPAPDC3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
328
Applicable Applications for anti-PPAPDC3 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 19 amino acid peptide from near the amino of terminus human PPAPDC3.
Target Name
PPAPDC3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Western Blot (WB)

(Western blot analysis of PPAPDC3 in mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 ug/mL.)

Western Blot (WB) (Western blot analysis of PPAPDC3 in mouse heart tissue lysate with PPAPDC3 antibody at (A) 1 and (B) 2 ug/mL.)
Related Product Information for anti-PPAPDC3 antibody
PPAPDC3, also known as nuclear envelope transmembrane protein 39 (NET39), was initially discovered in an in silico screen for secreted or membrane proteins. It is a member of the PAP2 superfamily of phosphatases and haloperoxidases. PPAPDC3 has recently been shown to act as a negative regulator of myoblast differentiation by diminishing the activity of the mammalian target of rapamycin TOR. PPAPDC3 is highly expressed in cardiac and skeletal muscle and becomes strongly upregulated during cultured myoblast differentiation tissues. Overexpression of PPAPDC3 in myoblasts repressed myogenesis while knockdown by RNA interference promoted differentiation indicating its part in the regulatory mechanism for myogenesis.
Product Categories/Family for anti-PPAPDC3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
Molecular Weight
29,448 Da
NCBI Official Full Name
phosphatidic acid phosphatase type 2 domain containing 3, isoform CRA_a, partial
NCBI Official Synonym Full Names
phosphatidic acid phosphatase type 2 domain containing 3
NCBI Official Symbol
PPAPDC3
NCBI Official Synonym Symbols
NET39; C9orf67
NCBI Protein Information
probable lipid phosphate phosphatase PPAPDC3
UniProt Protein Name
Probable lipid phosphate phosphatase PPAPDC3
UniProt Gene Name
PPAPDC3
UniProt Synonym Gene Names
C9orf67
UniProt Entry Name
PPAC3_HUMAN

Uniprot Description

PPAPDC3: Plays a role as negative regulator of myoblast differentiation, in part through effects on MTOR signaling. Has no detectable enzymatic activity. Belongs to the PA-phosphatase related phosphoesterase family.

Protein type: EC 3.1.3.-; Membrane protein, multi-pass; Membrane protein, integral; Hydrolase

Chromosomal Location of Human Ortholog: 9q34.13

Cellular Component: endoplasmic reticulum membrane; integral to membrane; nuclear envelope

Molecular Function: hydrolase activity

Biological Process: metabolic process

Research Articles on PPAPDC3

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Product Notes

The PPAPDC3 ppapdc3 (Catalog #AAA9402153) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPAPDC3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PPAPDC3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the PPAPDC3 ppapdc3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPAPDC3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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