Western Blot (WB)
(Western blot analysis of PLEKHM3 in mouse skeletal muscle tissue lysate with PLEKHM3 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit PLEKHM3 Polyclonal Antibody | anti-PLEKHM3 antibody
PLEKHM3 Antibody
Gene Names
PLEKHM3; DAPR; PLEKHM1L
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
PLEKHM3; Polyclonal Antibody; PLEKHM3 Antibody; Pleckstrin homology domain containing family M member 3; PLEKHM1L; DAPR; anti-PLEKHM3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
761
Applicable Applications for anti-PLEKHM3 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 13 amino acid peptide from near the carboxy terminus of human PLEKHM3.
Target Name
PLEKHM3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of PLEKHM3 in mouse skeletal muscle tissue lysate with PLEKHM3 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of PLEKHM3 in mouse skeletal muscle tissue lysate with PLEKHM3 antibody at (A) 1 and (B) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PLEKHM3 in human brain tissue with PLEKHM3 antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of PLEKHM3 in human brain tissue with PLEKHM3 antibody at 5 ug/mL.)
Related Product Information for anti-PLEKHM3 antibody
PLEKHM3, also known as DAPR, is a member of the M family of Pleckstrin homology domain-containing proteins. PLEKHM3 was initially identified through chromatin immunoprecipitation and CpG microarray analysis examining proteins regulated by myocyte-enhancing factor 2. In C2C12 myoblast cells, PLEKHM3 binds to the PI3K signaling member protein kinase B in the cytosol prior to differentiation into myotubes. Following the initiation of differentiation, PLEKHM3 was also found in membrane fractions. Knockdown of PLEKHM3 expression by RNAi resulted in the inhibition of myotube formation, suggesting that PLEKHM3 is a key component required by myoblasts for orchestrating their differentiation during myogenesis.
Product Categories/Family for anti-PLEKHM3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
59,587 Da
NCBI Official Full Name
pleckstrin homology domain-containing family M member 3
NCBI Official Synonym Full Names
pleckstrin homology domain containing, family M, member 3
NCBI Official Symbol
PLEKHM3
NCBI Official Synonym Symbols
DAPR; PLEKHM1L
NCBI Protein Information
pleckstrin homology domain-containing family M member 3
UniProt Protein Name
Pleckstrin homology domain-containing family M member 3
Protein Family
UniProt Gene Name
PLEKHM3
UniProt Synonym Gene Names
PLEKHM1L; PH domain-containing family M member 3
UniProt Entry Name
PKHM3_HUMAN
Uniprot Description
PLEKHM3: 3 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 2q33.3
Molecular Function: metal ion binding
Research Articles on PLEKHM3
Similar Products
Product Notes
The PLEKHM3 plekhm3 (Catalog #AAA9411592) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PLEKHM3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PLEKHM3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the PLEKHM3 plekhm3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PLEKHM3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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