Western Blot (WB)
(Sample Data: Representative western blot with Anti-HSP90beta (1:1000) using 20ng of human recombinant HSP90alpha and HSP90beta.)
Rabbit HSP90 beta Polyclonal Antibody | anti-HSP90beta antibody
Anti-HSP90 beta
Reactivity
Western blot of human, mouse HSP90bHSP90b from other species may also be detectable
Applications
Western Blot
Purity
Affinity chromatography
Synonyms
HSP90 beta; Polyclonal Antibody; Anti-HSP90 beta; anti-HSP90beta antibody
Host
Rabbit
Reactivity
Western blot of human, mouse HSP90b
HSP90b from other species may also be detectable
HSP90b from other species may also be detectable
Clonality
Polyclonal
Specificity
Recognizes the HSP90beta protein
Purity/Purification
Affinity chromatography
Form/Format
PBS pH7.4, 0.02% sodium azide, 50% glycerol
Applicable Applications for anti-HSP90beta antibody
Western Blot (WB)
Application Notes
WB: 22037:23036
Immunogen
Synthetic peptide corresponding to amino acids 252-256 of human HSP90beta
Preparation and Storage
Store at 4 degree C (add 0.1% NaN3) for several months, and at -20 degree C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.
Western Blot (WB)
(Sample Data: Representative western blot with Anti-HSP90beta (1:1000) using 20ng of human recombinant HSP90alpha and HSP90beta.)
Western Blot (WB)
(Sample Data: Representative western blot with Anti-HSP90beta (1:1000) using 20ng of human recombinant HSP90alpha and HSP90beta.)
Western Blot (WB)
(Sample Data: Representative western blot with Anti-HSP90beta (1:1000) using 3 ug, 10 ug, and 30 ug of HeLa cell lysate.)
Western Blot (WB)
(Sample Data: Representative western blot with Anti-HSP90beta (1:1000) using 3 ug, 10 ug, and 30 ug of HeLa cell lysate.)
Related Product Information for anti-HSP90beta antibody
HSP90beta is a member of the HSP90 family of proteins which are important molecular chaperones involved in signal transduction, cell cycle control, stress management, and folding, degradation, and transport of proteins (1). HSP90 proteins have been found in a variety of organisms suggesting that they are ancient and conserved. HSP90 binds to client proteins (such as steroid receptors, AKT, Bcr-Abl, Apaf-1, survivin, cyclin dependent kinases) and acts as a molecular chaperone. Failure of HSP90 chaperone activity leads to misfolding of client proteins, which leads to ubiquitination and proteasome degradation, and thus deregulation of cellular homeostasis (2).
Product Categories/Family for anti-HSP90beta antibody
References
1. Csermely, P. et al: The 90-kDa molecular chaperone family: structure, function, and clinical applications. Pharmacol Ther. 1998 Aug;79(2):129-68.
2. Georgakis, G.V. et al: Heat-shock protein 90 inhibitors in cancer therapy: 17AAG and beyond. Future Oncol. 2005 Apr;1(2):273-81.
2. Georgakis, G.V. et al: Heat-shock protein 90 inhibitors in cancer therapy: 17AAG and beyond. Future Oncol. 2005 Apr;1(2):273-81.
Similar Products
Product Notes
The HSP90beta (Catalog #AAA515994) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-HSP90 beta reacts with Western blot of human, mouse HSP90b HSP90b from other species may also be detectable and may cross-react with other species as described in the data sheet. AAA Biotech's HSP90 beta can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 22037:23036. Researchers should empirically determine the suitability of the HSP90beta for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "HSP90 beta, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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