Dilution Information
Mouse anti-Human IFN-Gamma Monoclonal Antibody | anti-IFN-Gamma antibody
IFN-Gamma (BSB-161)
Reactivity
Human
Synonyms
IFN-Gamma; Monoclonal Antibody; IFN-Gamma (BSB-161); IGN-y; IFNy; IFN y; anti-ifn-y; anti-ifny; anti-ifn y; gamma; ifn-gamma; ifn gamma; anti-ifn-gamma; anti-IFN-Gamma antibody
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
BSB-161
Form/Format
Paraffin, Frozen
Anti-IFN-y is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Anti-IFN-y is a rabbit monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Recombinant human IFN-gamma protein.
Control
Stomach, Fallopian Tube, Colon, Lung Adenocarcinoma, Ductal Breast Carcinoma, Pancreatic Adenocarcinoma
Localization
Cytoplasmic, Membranous
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(IFN-y Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue Tissue)
Immunohistochemistry (IHC)
(IFN-y Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Lung Tissue Tissue)
Related Product Information for anti-IFN-Gamma antibody
IFN-gamma is a dimerized soluble cytokine and the only member of the type II interferon. In humans, IFN-gamma is encoded by the IFNG gene and is critical for innate and adaptive immunity against viral, some bacterial and protozoal infections. IFN-gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 Th1 and CD8 cytotoxic T lymphocytes effector T cells once antigen-specific immunity develops as part of the adaptive immune response. IFN-gamma is also produced by non-cytotoxic innate lymphoid cells.
IFN-gamma interacts with its receptors interferon gamma receptor 1 and interferon gamma receptor 2 and activates them. IFN-gamma binding to the receptors activates the JAK-STAT pathway. IFN-gamma also binds to the glycosaminoglycan heparan sulfate and inhibits its biological activity. IFN-gamma is used to treat Chronic Granulomatous Disease and Osteopetrosis, also has potential as cancer immunotherapy to improve survival in Bladder Carcinoma, Melanoma, and Ovarian Carcinoma.
IFN-gamma interacts with its receptors interferon gamma receptor 1 and interferon gamma receptor 2 and activates them. IFN-gamma binding to the receptors activates the JAK-STAT pathway. IFN-gamma also binds to the glycosaminoglycan heparan sulfate and inhibits its biological activity. IFN-gamma is used to treat Chronic Granulomatous Disease and Osteopetrosis, also has potential as cancer immunotherapy to improve survival in Bladder Carcinoma, Melanoma, and Ovarian Carcinoma.
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Product Notes
The IFN-Gamma (Catalog #AAA370500) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The IFN-Gamma (BSB-161) reacts with Human and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "IFN-Gamma, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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