Dilution Information
Mouse ACE-2 Monoclonal Antibody | anti-ACE-2 antibody
ACE-2 (BSB-135)
Reactivity
Human, Mouse, Rat
Synonyms
ACE-2; Monoclonal Antibody; ACE-2 (BSB-135); ace2; ace-2; anti-ace2; anti-ace-2; sars-cov-2 receptors; sars cov-2 receptors; covid-19 receptors; sars-cov-2 antibodies sars-cov-2 ihc; sars-cov-2 immunohistochemistry; anti-ACE-2 antibody
Host
Mouse
Reactivity
Human, Mouse, Rat
Clonality
Monoclonal
Isotype
IgG1
Clone Number
BSB-135
Form/Format
Paraffin, Frozen
ACE2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
ACE2 is a mouse monoclonal antibody derived from cell culture supernatant that is concentrated, dialyzed, filter sterilized and diluted in buffer pH7.5, containing BSA and sodium azide as a preservative.
Immunogen
Synthetic Peptide corresponding to the C-terminal of ACE2 of human origin.
Control
Kidney, Testis, Brain, Colon, Fallopian Tube
Localization
Membranous, Cytoplasmic
Preparation and Storage
Store at 2-8 degree C (Control Slides: Store at 20-25 degree C)
Dilution Information
Dilution Information
Immunohistochemistry (IHC)
(ACE2 Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Testis Tissue)
Immunohistochemistry (IHC)
(ACE2 Antibody Immunohistochemistry on a FFPE SARS-CoV-2 Infected Testis Tissue)
Related Product Information for anti-ACE-2 antibody
Angiotensin Converting Enzyme 2 is a dipeptidyl carboxydipeptidase active in the renin-angiotensin pathway, which helps regulate cardiovascular and renal functions. ACE2 is a secreted protein that cleaves angiotensin I (AngI) into angiotensin 1-9, and angiotensin II (AngII) into vasodilator angiotensin 1-7. ACE2 is expressed in the heart and kidney, where it may counteract vasoconstriction by inactivating Ang II. It is also found in the GI tract, lungs, and testis, in endothelial cells and less in vascular smooth muscle cells. ACE2 can contribute to tumor inhibition by inactivating AngII, which has been found to participate in tumor proliferation, angiogenesis, and metastasis.
ACE2 has shown inhibitory effects on lung, prostate, breast, and liver cancer through various signaling mechanisms, and its expression may be correlated with immune cell penetration into the tissue. ACE2 also functions as the main receptor for the spike glycoprotein of human coronaviruses HCoV-NL63, SARS-CoV and SARS-CoV-2.
ACE2 has shown inhibitory effects on lung, prostate, breast, and liver cancer through various signaling mechanisms, and its expression may be correlated with immune cell penetration into the tissue. ACE2 also functions as the main receptor for the spike glycoprotein of human coronaviruses HCoV-NL63, SARS-CoV and SARS-CoV-2.
Similar Products
Product Notes
The ACE-2 (Catalog #AAA370468) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The ACE-2 (BSB-135) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. It is sometimes possible for the material contained within the vial of "ACE-2, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
