Testing Data
(Figure A. FITC conjugated mouse anti porcine CD3 and purified mouse IgG2a isotype control detected with RPE conjugated goat anti mouse IgG . Figure B. FITC conjugated mouse anti porcine CD3 and purified mouse anti porcine CD45 detected with RPE conjugated goat anti mouse IgG . All experiments performed on red cell lysed porcine blood gated on lymphocytes. Data acquired on the ZE5 Cell Analyzer.)
Mouse anti-Pig CD45 Monoclonal Antibody | anti-CD45 antibody
Mouse Anti Pig CD45 Allotypic Variant
Immunohistology (FR/P/R): 1:10
It is recommended to aliquot and store at -20°C on receipt.
When thawed, aliquot the sample as needed.
Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody.
Storage in frost-free freezers is not recommended.
Testing Data
(Figure A. FITC conjugated mouse anti porcine CD3 and purified mouse IgG2a isotype control detected with RPE conjugated goat anti mouse IgG . Figure B. FITC conjugated mouse anti porcine CD3 and purified mouse anti porcine CD45 detected with RPE conjugated goat anti mouse IgG . All experiments performed on red cell lysed porcine blood gated on lymphocytes. Data acquired on the ZE5 Cell Analyzer.)
Testing Data
(Figure A. FITC conjugated mouse anti porcine CD3 and purified mouse IgG2a isotype control detected with RPE conjugated goat anti mouse IgG . Figure B. FITC conjugated mouse anti porcine CD3 and purified mouse anti porcine CD45 detected with RPE conjugated goat anti mouse IgG . All experiments performed on red cell lysed porcine blood gated on lymphocytes. Data acquired on the ZE5 Cell Analyzer.)
Testing Data
(Mouse anti Porcine CD45 antibody, clone MAC323 used to illustrate inflammatory cells in an implant model by immunohistochemistryImage caption:CD45 histology at 6M.OCT demonstrated the development of a highly heterogeneous neointima with inflammation (F; CD45).From: van Ditzhuijzen NS, Kurata M, van den Heuvel M, Sorop O, van Duin RWB, Krabbendam-Peters I, et al. (2017)Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine.)
Testing Data
(Mouse anti Porcine CD45 antibody, clone MAC323 used to illustrate inflammatory cells in an implant model by immunohistochemistryImage caption:CD45 histology at 6M.OCT demonstrated the development of a highly heterogeneous neointima with inflammation (F; CD45).From: van Ditzhuijzen NS, Kurata M, van den Heuvel M, Sorop O, van Duin RWB, Krabbendam-Peters I, et al. (2017)Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine.)
Testing Data
(Mouse anti Porcine CD45 antibody, clone MAC323 used to illustrate inflammatory cells in an implant model by immunohistochemistry on cryostat sections.Image caption:Collagen poor areas in peri-strut regions and neointima showing leucocyte infiltration (C, F; CD45).From: van Ditzhuijzen NS, Kurata M, van den Heuvel M, Sorop O, van Duin RWB, Krabbendam-Peters I, et al. (2017)Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine.)
Testing Data
(Mouse anti Porcine CD45 antibody, clone MAC323 used to illustrate inflammatory cells in an implant model by immunohistochemistry on cryostat sections.Image caption:Collagen poor areas in peri-strut regions and neointima showing leucocyte infiltration (C, F; CD45).From: van Ditzhuijzen NS, Kurata M, van den Heuvel M, Sorop O, van Duin RWB, Krabbendam-Peters I, et al. (2017)Neoatherosclerosis development following bioresorbable vascular scaffold implantation in diabetic and non-diabetic swine.)
Testing Data
(Figure A. FITC conjugated Mouse anti Pig CD3 and Mouse IgG2a isotype control detected with Goat anti Mouse IgG2a:RPE . Figure B. FITC conjugated Mouse anti Pig CD3 and Mouse anti Pig CD45RC detected with Goat anti Mouse IgG2a:RPE . All experiments performed on red cell lysed porcine blood gated on lymphocytes in the presence of 10% pig serum. Data acquired on the ZE5 Cell Analyzer.)
Testing Data
(Figure A. FITC conjugated Mouse anti Pig CD3 and Mouse IgG2a isotype control detected with Goat anti Mouse IgG2a:RPE . Figure B. FITC conjugated Mouse anti Pig CD3 and Mouse anti Pig CD45RC detected with Goat anti Mouse IgG2a:RPE . All experiments performed on red cell lysed porcine blood gated on lymphocytes in the presence of 10% pig serum. Data acquired on the ZE5 Cell Analyzer.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012]
Research Articles on CD45
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Product Notes
The CD45 (Catalog #AAA225627) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Anti Pig CD45 Allotypic Variant reacts with Pig and may cross-react with other species as described in the data sheet. AAA Biotech's CD45 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC) Frozen/Paraffin. Flow Cytometry : 1:25-1:100Immunohistology (FR/P/R): 1:10. Researchers should empirically determine the suitability of the CD45 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CD45, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.
Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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