LPAL2 recombinant protein

LPAL2 Protein, Human, Recombinant (mFc Tag)

Cat. Num. AAA8121562

• Purity: >80% as determined by SDS-PAGE
• Synonyms: LPAL2; LPAL2 Protein; Human; Recombinant (mFc Tag); Human LPAL2 Protein (Fc Tag); apo(a)rg-C Protein; APOA2 Protein; APOAL Protein; APOARGC Protein; lipoprotein; Lp(a)-like 2; pseudogene; LPAL2 recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >80% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Met1-Ala132

• Species: Human
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Gly 22
• Tag: C-mouse IgG1-Fc
• Protein Construction: A DNA sequence encoding the human LPAL2 (Q16609)(Met1-Ala132) was expressed with the Fc region of mouse IgG1 at the C-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

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Related Product Information for LPAL2 recombinant protein

Background: LPAL2 (Lipoprotein(A) Like 2, Pseudogene) is a Pseudogene. This gene is similar to the lipoprotein, Lp(a) gene, but all transcripts produced by this gene contain a truncated open reading frame and are candidates for nonsense-mediated decay. Lipoprotein(a) [Lp(a)] level is an established risk factor for coronary artery disease and has been implicated in carotid artery disease (CAAD). Mutations in the solute carrier family 22 member 3 (SLC22A3), lipoprotein (a)-like 2 (LPAL2), and the lipoprotein (a)(LPA) gene cluster, which encodes apolipoprotein (a) [apo (a)] of the lipoprotein (a) [Lp (a)] lipoprotein particle, have been suggested to contribute to the risk of coronary artery disease (CAD). Recent genome-wide association studies have identified that genetic variants in the SLC22A3-LPAL2-LPA gene cluster influence plasma lipoprotein(a) [Lp(a)] concentration.

NCBI and Uniprot Product Information

• NCBI GI #: 74739884
• UniProt Accession #: Q16609; E1P5B4
• Molecular Weight: 14,886 Da
• NCBI Official Full Name: Putative apolipoprotein(a)-like protein 2
• UniProt Protein Name: Putative apolipoprotein(a)-like protein 2
• Protein Family: Putative apolipoprotein(a)-like protein
• UniProt Gene Name: LPAL2
• UniProt Synonym Gene Names: APOARGC; Apo(a)-like protein 2; Lp(a)-liker protein 2; Apo(a)rg-C
• UniProt Entry Name: LPAL2_HUMAN