Testing Data
Human Soluble Epoxide Hydrolase Assay Kit
Soluble Epoxide Hydrolase Inhibitor Screening Kit (Fluorometric)
Reactivity
Human
Synonyms
Soluble Epoxide Hydrolase; Soluble Epoxide Hydrolase Inhibitor Screening Kit (Fluorometric); Soluble Epoxide Hydrolase assay kit
Reactivity
Human
Detection Method
Fluorescence: Ex/Em 362/460nm
Features & Benefits
Simplest High-Throughput Assay To Screen Thioredoxin 1 Inhibitors
Rapid
Simple & sensitive
Convenient & HTS
Includes NCND (inhibitor control)
Screening/studying/characterizing soluble Epoxide Hydrolase inhibitors
Rapid
Simple & sensitive
Convenient & HTS
Includes NCND (inhibitor control)
Screening/studying/characterizing soluble Epoxide Hydrolase inhibitors
Preparation and Storage
Store at -20 degree C
Shelf life: ~12 months
Shelf life: ~12 months
Testing Data
Testing Data
Testing Data
Testing Data
Related Product Information for Soluble Epoxide Hydrolase assay kit
Soluble Epoxide Hydrolase (EC 3.3.2.10) is a cytosolic enzyme with highest expression in the liver but present ubiquitously in several organs including the kidney, pancreatic islets, pituitary gland, lymphoid tissues, muscles, and the gastrointestinal tract. It catalyzes the hydrolysis of epoxyeicosatrienoic acids (EETs), i.e., epoxides derived from cytochrome P-450 mediated metabolism of arachidonic acid, to form vicinal diols. The EETs cause vasodilation and have anti-inflammatory actions. Since the EETs are hydrolyzed to diols through soluble epoxide hydrolase, the inhibition of this enzyme is likely to enhance the beneficial properties of EETs. This makes soluble epoxide hydrolase a very useful target for cardiovascular and pain medicine. Soluble Epoxide Hydrolase Inhibitor Screening Kit is a micro-plate based fluorometric kit for screening sEH inhibitors. Its assay principle is based on the hydrolysis of a non-fluorescent substrate to a fluorescent product by sEH. It uses N-Cyclohexyl-N?-dodecylurea (NCND), a well-known sEH inhibitor, as positive control. The kit provides a simple and fast method to screen/ characterize potential sEH inhibitors.
Product Categories/Family for Soluble Epoxide Hydrolase assay kit
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Product Notes
The Human Soluble Epoxide Hydrolase (Catalog #AAA849697) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA849697 Assay Kit recognizes Human Soluble Epoxide Hydrolase. It is sometimes possible for the material contained within the vial of "Soluble Epoxide Hydrolase, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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