Typical Testing Data/Standard Curve (for reference only)
Cyclooxygenase-1 (COX-1) Assay Kit | cox-1 assay kit
Cyclooxygenase-1 (COX-1) Inhibitor Screening Kit (Fluorometric)
Synonyms
Cyclooxygenase-1 (COX-1); Cyclooxygenase-1 (COX-1) Inhibitor Screening Kit (Fluorometric); Prostaglandin-Endoperoxide Synthase 1 Inhibitor Screening Kit (Fluorometric); PTGS1 Inhibitor Screening Kit (Fluorometric); cox-1 assay kit
Sequence Length
624
Application Notes
Screening/studying/characterizing COX-1 inhibitors.
Detection Method
Fluorescence (Ex/Em 535/587 nm)
Features & Benefits
Simple method to screen COX-1 inhibitors
High-throughput
Includes Inhibitor Control, SC560
High-throughput
Includes Inhibitor Control, SC560
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for cox-1 assay kit
Product Information: COX-1 Inhibitor Screening Kit (Fluorometric): Simple method to screen/study/characterize Cyclooxygenase-1 Inhibitors, includes COX-1 Inhibitor, SC560. Convenient & Reliable. 100 Assays.
Background: Cyclooxygenase (COX), also known as prostaglandin-endoperoxide synthase (PTGS, EC 1.14.99.1), is an enzyme that is responsible for the formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. COX is the central enzyme in the biosynthetic pathway to prostanoids from arachidonic acid. There are two known isoenzymes: COX-1 and COX-2. COX-1 is constitutively expressed in many tissues and is the predominant form in gastric mucosa and in kidney. COX-2 is not expressed under normal conditions in most cells, but elevated levels are found during inflammation. Pharmacological inhibition of COX by non-steroidal anti-inflammatory drugs (NSAID) can provide relief from the symptoms of inflammation and pain. MyBioSource's COX-1 Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of COX-1 inhibitors. The assay is based on the fluorometric detection of Prostaglandin G2, the intermediate product generated by the COX enzyme.
Summary: Detection method- Fluorescence (Ex/Em 535/587 nm)
Applications- Screening/studying/characterizing COX-1 inhibitors.
Background: Cyclooxygenase (COX), also known as prostaglandin-endoperoxide synthase (PTGS, EC 1.14.99.1), is an enzyme that is responsible for the formation of important biological mediators called prostanoids, including prostaglandins, prostacyclin and thromboxane. COX is the central enzyme in the biosynthetic pathway to prostanoids from arachidonic acid. There are two known isoenzymes: COX-1 and COX-2. COX-1 is constitutively expressed in many tissues and is the predominant form in gastric mucosa and in kidney. COX-2 is not expressed under normal conditions in most cells, but elevated levels are found during inflammation. Pharmacological inhibition of COX by non-steroidal anti-inflammatory drugs (NSAID) can provide relief from the symptoms of inflammation and pain. MyBioSource's COX-1 Inhibitor Screening Kit offers a rapid, simple, sensitive, and reliable test suitable for high-throughput screening of COX-1 inhibitors. The assay is based on the fluorometric detection of Prostaglandin G2, the intermediate product generated by the COX enzyme.
Summary: Detection method- Fluorescence (Ex/Em 535/587 nm)
Applications- Screening/studying/characterizing COX-1 inhibitors.
Product Categories/Family for cox-1 assay kit
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
cyclooxygenase-1
NCBI Official Symbol
cox-1
NCBI Protein Information
cyclooxygenase-1
Similar Products
Product Notes
The cox-1 (Catalog #AAA841706) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Screening/studying/characterizing COX-1 inhibitors. Researchers should empirically determine the suitability of the cox-1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cyclooxygenase-1 (COX-1), Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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