Rabbit PHKG1 Polyclonal Antibody | anti-PHKG1 antibody

PHKG1 Rabbit Polyclonal

Cat. Num. AAA7602627

• Gene Names: PHKG1; PHKG
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: PHKG1; Polyclonal Antibody; PHKG1 Rabbit Polyclonal; anti-PHKG1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 387

• Applicable Applications for anti-PHKG1 antibody: ELISA (EIA), Western Blot (WB)
• Immunogen: Phosphorylase kinase, gamma 1 (muscle)
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Western Blot (WB)

(mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with MBS7602627 (PHKG1 antibody) at dilution of 1:500)

NCBI and Uniprot Product Information

• NCBI GI #: 5453882
• NCBI GeneID: 5260
• NCBI Accession #: NP_006204.1
• NCBI GenBank Nucleotide #: NM_006213.4
• Molecular Weight: 48,867 Da
• NCBI Official Full Name: phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform isoform 2
• NCBI Official Synonym Full Names: phosphorylase kinase catalytic subunit gamma 1
• NCBI Official Symbol: PHKG1
• NCBI Official Synonym Symbols: PHKG
• NCBI Protein Information: phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
• UniProt Protein Name: Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
• Protein Family: Phosphorylase b kinase
• UniProt Gene Name: PHKG1
• UniProt Synonym Gene Names: PHKG; PHK-gamma-M
• UniProt Entry Name: PHKG1_HUMAN

NCBI Description

This gene is a member of the Ser/Thr protein kinase family and encodes a protein with one protein kinase domain and two calmodulin-binding domains. This protein is the catalytic member of a 16 subunit protein kinase complex which contains equimolar ratios of 4 subunit types. The complex is a crucial glycogenolytic regulatory enzyme. This gene has two pseudogenes at chromosome 7q11.21 and one at chromosome 11p11.12. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Uniprot Description

PHKG1: a Ca(2+)/calmodulin-dependent protein kinase of the PHK family. Phosphorylase kinase is a polymer of 16 chains, four each of alpha, beta, gamma, and delta. Alpha and beta are regulatory chains, gamma is the catalytic chain, and delta is calmodulin.

Protein type: Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.26; EC 2.7.11.1; EC 2.7.11.19; Protein kinase, CAMK; CAMK group; PHK family

Chromosomal Location of Human Ortholog: 7p11.2

Cellular Component: cytosol; phosphorylase kinase complex

Molecular Function: ATP binding; calmodulin binding; enzyme binding; phosphorylase kinase activity; tau-protein kinase activity

Biological Process: carbohydrate metabolic process; glycogen biosynthetic process; glycogen catabolic process; protein amino acid phosphorylation