Typical Testing Data/Standard Curve (for reference only)
Factor Xa Assay Kit
Factor Xa Inhibitor Screening Kit (Fluorometric)
Synonyms
Factor Xa; Factor Xa Inhibitor Screening Kit (Fluorometric); Factor Xa assay kit
Application Notes
Screening potential inhibitors of Factor Xa
Characterizing/studying Factor Xa inhibitors in plasma samples
Characterizing/studying Factor Xa inhibitors in plasma samples
Detection Method
Fluorescence (Ex/Em = 350/450 nm)
Features & Benefits
Simple and reliable test to screen/study/characterize Fxa inhibitors
High-throughput
Includes Inhibitor Control (GGACK Dihydrochloride)
High-throughput
Includes Inhibitor Control (GGACK Dihydrochloride)
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for Factor Xa assay kit
Product Information: Factor Xa Inhibitor Screening Kit (Fluorometric): High-Throughput assay to screen FXa Inhibitors. Rapid, Simple & Sensitive. Includes Inhibitor Control, GGACK Dihydrochloride. 100 Assays.
Background: Factor Xa (FXa) is the activated form of the coagulation factor X (Stuart-Power factor, thrombokinase, prothrombinase, thromboplastin, E.C.3.4.21.6). Factor X, a serine endopeptidase, plays an important role at several stages of the coagulation pathway. It acts by converting prothrombin into active thrombin by complexing with activated co-factor V in the prothrombinase complex. Unfractionated heparin and various low molecular weight heparins bind to plasma cofactor Antithrombin to inactivate several coagulation factors including factor Xa. MyBioSource's Factor Xa inhibitor screening kit utilizes the ability of Factor Xa to cleave a synthetic substrate thereby releasing a fluorophore, AMC, which can be quantified by a fluorescence reader. In the presence of an inhibitor, the extent of the cleavage reaction is reduced or completely abolished. The loss in the fluorescence intensity can be correlated to the amount of inhibitor present in the assay solution. The Factor Xa Inhibitor Screening Kit is a simple, straightforward, high-throughput assay to screen Factor Xa inhibitors.
Summary: Detection method- Fluorescence (Ex/Em = 350/450 nm)
Applications: - Screening potential inhibitors of Factor Xa - Characterizing/studying Factor Xa inhibitors in plasma samples
Background: Factor Xa (FXa) is the activated form of the coagulation factor X (Stuart-Power factor, thrombokinase, prothrombinase, thromboplastin, E.C.3.4.21.6). Factor X, a serine endopeptidase, plays an important role at several stages of the coagulation pathway. It acts by converting prothrombin into active thrombin by complexing with activated co-factor V in the prothrombinase complex. Unfractionated heparin and various low molecular weight heparins bind to plasma cofactor Antithrombin to inactivate several coagulation factors including factor Xa. MyBioSource's Factor Xa inhibitor screening kit utilizes the ability of Factor Xa to cleave a synthetic substrate thereby releasing a fluorophore, AMC, which can be quantified by a fluorescence reader. In the presence of an inhibitor, the extent of the cleavage reaction is reduced or completely abolished. The loss in the fluorescence intensity can be correlated to the amount of inhibitor present in the assay solution. The Factor Xa Inhibitor Screening Kit is a simple, straightforward, high-throughput assay to screen Factor Xa inhibitors.
Summary: Detection method- Fluorescence (Ex/Em = 350/450 nm)
Applications: - Screening potential inhibitors of Factor Xa - Characterizing/studying Factor Xa inhibitors in plasma samples
Product Categories/Family for Factor Xa assay kit
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Product Notes
The Factor Xa (Catalog #AAA841634) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Screening potential inhibitors of Factor Xa Characterizing/studying Factor Xa inhibitors in plasma samples. Researchers should empirically determine the suitability of the Factor Xa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Factor Xa, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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