Typical Testing Data/Standard Curve (for reference only)
thrombin assay kit
Thrombin Inhibitor Screening Kit (Fluorometric)
Synonyms
Thrombin; Thrombin Inhibitor Screening Kit (Fluorometric); thrombin assay kit
Sequence Length
239
Application Notes
Screening potential inhibitors of thrombin
Characterize/study thrombin inhibitors
Characterize/study thrombin inhibitors
Detection Method
Fluorescence (Ex/Em = 350/450 nm)
Features & Benefits
Rapid & simple
Reliable test for screening potential inhibitors of thrombin
Includes thrombin Inhibitor [PPACK Dihydrochloride]
Reliable test for screening potential inhibitors of thrombin
Includes thrombin Inhibitor [PPACK Dihydrochloride]
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Related Product Information for thrombin assay kit
Product Information: Thrombin Inhibitor Screening Kit (Fluorometric): Rapid, simple & reliable test for screening/characterizing/studying potential inhibitors of thrombin. 100 assays
Background: Thrombin enzyme (Factor IIa) is an important clotting factor that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a serine protease (EC 3.4.21.5) that catalyzes many coagulation-related reactions. Thrombin inhibitors are used as anticoagulants to prevent arterial and venous thrombosis. Some of these inhibitors are currently in clinical use while others are in clinical development. MyBioSource's Thrombin Inhibitor Screening Kit utilizes the ability of Thrombin to cleave a synthetic AMC-based peptide substrate to release AMC, which can be detected by measuring its fluorescence at Ex/Em = 350/450 nm. In the presence of Thrombin specific inhibitors, the extent of cleavage reaction is reduced or completely abolished. The loss in the fluorescence intensity can be correlated to the amount of inhibitor present in the assay solution. The kit provides a simple and rapid method to screen potential inhibitors of Thrombin.
Summary: Detection Method - Fluorescence (Ex/Em = 350/450 nm)
Application: - Screening potential inhibitors of thrombin - Characterize/study thrombin inhibitors
Background: Thrombin enzyme (Factor IIa) is an important clotting factor that controls the transformation of soluble fibrinogen to insoluble active fibrin strands. Thrombin is a serine protease (EC 3.4.21.5) that catalyzes many coagulation-related reactions. Thrombin inhibitors are used as anticoagulants to prevent arterial and venous thrombosis. Some of these inhibitors are currently in clinical use while others are in clinical development. MyBioSource's Thrombin Inhibitor Screening Kit utilizes the ability of Thrombin to cleave a synthetic AMC-based peptide substrate to release AMC, which can be detected by measuring its fluorescence at Ex/Em = 350/450 nm. In the presence of Thrombin specific inhibitors, the extent of cleavage reaction is reduced or completely abolished. The loss in the fluorescence intensity can be correlated to the amount of inhibitor present in the assay solution. The kit provides a simple and rapid method to screen potential inhibitors of Thrombin.
Summary: Detection Method - Fluorescence (Ex/Em = 350/450 nm)
Application: - Screening potential inhibitors of thrombin - Characterize/study thrombin inhibitors
Product Categories/Family for thrombin assay kit
NCBI and Uniprot Product Information
Similar Products
Product Notes
The Thrombin thrombin (Catalog #AAA841768) is an Assay Kit and is intended for research purposes only. The product is available for immediate purchase. Screening potential inhibitors of thrombin Characterize/study thrombin inhibitors. Researchers should empirically determine the suitability of the Thrombin thrombin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Thrombin, Assay Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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