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Testing Data (The OmniKine Murine sRANK Ligand ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine sRANK Ligand proteins within the range of 62.5-5000 pg/ml.)

Mouse sRANK Ligand ELISA Kit | Tnfrsf11a elisa kit

sRANK Ligand (Murine) OmniKine ELISA Kit

Gene Names
Tnfrsf11a; OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R
Reactivity
Mouse
Synonyms
sRANK Ligand; sRANK Ligand (Murine) OmniKine ELISA Kit; Tumor necrosis factor receptor superfamily member 11A; Osteoclast differentiation factor receptor; ODFR; Receptor activator of NF-KB; CD265; Rank; Tnfrsf11a elisa kit
Ordering
For Research Use Only!
Reactivity
Mouse
Specificity
The OmniKine Murine sRANK-Ligand ELISA is capable of recognizing both recombinant and naturally produced Murine sRANK-Ligand proteins. The antigens listed below were tested at 50 ng/ml and exhibited 100% cross reactivity.
Rat: sRANKL
The antigens listed below were tested at 50 ng/ml and did not exhibit significant cross reactivity or interference.
Human: sFas, sFasL, sCD40L, sRANKL, sRANKR, TNFalpha, TNFbeta, sTRAIL
Murine: April, sCD40L, LIGHT, sRANKL, TNFalpha
Form/Format
12 x 8-Well Microstrips
Sequence Length
625
Samples
Plasma, serum, lysate
Assay Type
Sandwich ELISA
Detection Range
625-5000 pg/ml
Sensitivity
625-5000 pg/ml
Detection Method
Colorimetric 450 nm
Subtype
None
Preparation and Storage
Store at 4 degree C for 6 months.

Testing Data

(The OmniKine Murine sRANK Ligand ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine sRANK Ligand proteins within the range of 62.5-5000 pg/ml.)

Testing Data (The OmniKine Murine sRANK Ligand ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Murine sRANK Ligand proteins within the range of 62.5-5000 pg/ml.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
66,621 Da
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 11A
NCBI Official Synonym Full Names
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
NCBI Official Symbol
Tnfrsf11a
NCBI Official Synonym Symbols
OFE; ODFR; Rank; Ly109; mRANK; TRANCE-R
NCBI Protein Information
tumor necrosis factor receptor superfamily member 11A
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 11A
UniProt Gene Name
Tnfrsf11a
UniProt Synonym Gene Names
Rank; ODFR

Uniprot Description

TNFRSF11A: Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. Binds to the clefts between the subunits of the TNFSF11 ligand trimer to form a heterohexamer. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. Interacts (via cytoplasmic domain) with GAB2. Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1|1 E2.1

Cellular Component: cell surface; cytosol; external side of plasma membrane; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane

Molecular Function: cytokine binding; metal ion binding; protein binding; transmembrane receptor activity; tumor necrosis factor-activated receptor activity

Biological Process: adaptive immune response; circadian temperature homeostasis; immune response; lymph node development; multicellular organism development; ossification; osteoclast differentiation; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of transcription factor activity; regulation of apoptosis; regulation of cell proliferation; response to cytokine; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway

Research Articles on Tnfrsf11a

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Product Notes

The Mouse Tnfrsf11a tnfrsf11a (Catalog #AAA9501926) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9501926 ELISA Kit recognizes Mouse Tnfrsf11a. It is sometimes possible for the material contained within the vial of "sRANK Ligand, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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