Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Tropomodulin-2 (TMOD2) Standard Curve.)
Human Tropomodulin-2 (TMOD2) ELISA Kit | TMOD2 elisa kit
Human Tropomodulin-2 (TMOD2) ELISA Kit
Gene Names
TMOD2; NTMOD; N-TMOD
Reactivity
Human
Synonyms
Tropomodulin-2 (TMOD2); Human Tropomodulin-2 (TMOD2) ELISA Kit; TMOD2; MGC39481; N-TMOD; NTMOD; neuronal tropomodulin; TMOD2 elisa kit
Reactivity
Human
Specificity
Human Tropomodulin-2 (TMOD2) ELISA Kit has high sensitivity and excellent specificity for detection of Human TMOD2. No significant cross-reactivity or interference between Human TMOD2 and analogues was observed.
Sequence Length
307
Assay Type
Sandwich ELISA (Quantitative)
Samples
Cell Culture Supernatants, Serum, Plasma, Other Biological Fluids
Detection Method
Colorimetric
Usage Notes
* Do not mix components from different kit lots or use reagents beyond the kit expiration date.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
* Allow all reagents to warm to room temperature for at least 30 minutes before opening.
* Pre-rinse the pipet tip with reagent, use fresh pipet tips for each sample, standard and reagent to avoid contamination.
* Unused wells must be kept desiccated at 4 degree C in the sealed bag provided.
* Mix Thoroughly is very important for the result. It is recommended using low frequency oscillator or slight hand shaking every 10 minutes.
* It is recommended that all samples and standards be assayed in duplicate or triplicate.
Preparation and Storage
Store at 2-8 degree C.
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Tropomodulin-2 (TMOD2) Standard Curve.)
Typical Testing Data/Standard Curve (for reference only)
(Fig.1. Human Tropomodulin-2 (TMOD2) Standard Curve.)
Related Product Information for TMOD2 elisa kit
Description: This Human Tropomodulin-2 (TMOD2) ELISA Kit employs a two-site sandwich ELISA to quantitate TMOD2 in samples. An antibody specific for TMOD2 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TMOD2 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TMOD2 is added to the wells. After washing, Streptavidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TMOD2 bound in the initial step. The color development is stopped and the intensity of the color is measured.
Background: TMOD2 encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. TMOD2 encodes a deduced 351-amino acid protein. Northern blot analysis demonstrated restricted expression of TMOD2 in neuronal tissues; an approximately 9.5-kb transcript was seen in all brain regions. Northern blot analysis showed that expression of mouse Tmod2 occurred as early as embryonic day 7 and progressively increased during development.
Background: TMOD2 encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. TMOD2 encodes a deduced 351-amino acid protein. Northern blot analysis demonstrated restricted expression of TMOD2 in neuronal tissues; an approximately 9.5-kb transcript was seen in all brain regions. Northern blot analysis showed that expression of mouse Tmod2 occurred as early as embryonic day 7 and progressively increased during development.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
NCBI Official Full Name
TMOD2 protein
NCBI Official Synonym Full Names
tropomodulin 2
NCBI Official Symbol
TMOD2
NCBI Official Synonym Symbols
NTMOD; N-TMOD
NCBI Protein Information
tropomodulin-2
UniProt Protein Name
Tropomodulin-2
Protein Family
UniProt Gene Name
TMOD2
UniProt Synonym Gene Names
NTMOD; N-Tmod
NCBI Description
This gene encodes a neuronal-specific member of the tropomodulin family of actin-regulatory proteins. The encoded protein caps the pointed end of actin filaments preventing both elongation and depolymerization. The capping activity of this protein is dependent on its association with tropomyosin. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Dec 2008]
Uniprot Description
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton ().
Research Articles on TMOD2
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Product Notes
The Human TMOD2 tmod2 (Catalog #AAA9713923) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9713923 ELISA Kit recognizes Human TMOD2. It is sometimes possible for the material contained within the vial of "Tropomodulin-2 (TMOD2), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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