Western Blot (WB)
(Western Blot: Sample: Mouse Liver lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse RANk Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Rabbit anti-Mouse Receptor Activator Of Nuclear Factor Kappa B (RANk) Polyclonal Antibody | anti-RANk antibody
Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B (RANk)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- LI QQGSKSIPPF QEPLEVGEND SLSQCFTGTE STVDSEGCDF TEPPSRTDSM PVSPEKHLTK EIEGDSCLPW VVSSNSTDGY TGSGNTPGED HEPFPGSLKC GPLPQCAYSM GFPSEAAASM AEAGVRPQDR
Immunocytochemistry in formalin fixed cells: 1:100-500
Immunohistochemistry in formalin fixed frozen section: 1:100-500
Immunohistochemistry in paraffin section: 1:50-200
Enzyme-linked Immunosorbent Assay: 1:100-200
Western Blot (WB)
(Western Blot: Sample: Mouse Liver lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse RANk Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Mouse Liver lysate; Primary Ab: 2ug/ml Rabbit Anti-Mouse RANk Antibody Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody )
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin-embedded Liver tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Testis Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Mouse Testis Tissue))
NCBI and Uniprot Product Information
Uniprot Description
TNFRSF11A: Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells. Binds to the clefts between the subunits of the TNFSF11 ligand trimer to form a heterohexamer. Interacts with TRAF1, TRAF2, TRAF3, TRAF5 and TRAF6. Interacts (via cytoplasmic domain) with GAB2. Ubiquitous expression with high levels in skeletal muscle, thymus, liver, colon, small intestine and adrenal gland.
Protein type: Membrane protein, integral
Chromosomal Location of Human Ortholog: 1|1 E2.1
Cellular Component: cell surface; cytosol; external side of plasma membrane; integral component of membrane; integral component of plasma membrane; membrane; plasma membrane
Molecular Function: cytokine binding; metal ion binding; protein binding; transmembrane receptor activity; tumor necrosis factor-activated receptor activity
Biological Process: adaptive immune response; circadian temperature homeostasis; immune response; lymph node development; multicellular organism development; ossification; osteoclast differentiation; positive regulation of JUN kinase activity; positive regulation of NF-kappaB transcription factor activity; positive regulation of transcription factor activity; regulation of apoptosis; regulation of cell proliferation; response to cytokine; response to lipopolysaccharide; tumor necrosis factor-mediated signaling pathway
Research Articles on RANk
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Product Notes
The RANk tnfrsf11a (Catalog #AAA2014411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Receptor Activator Of Nuclear Factor Kappa B (RANk) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Receptor Activator Of Nuclear Factor Kappa B (RANk) can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC) - Formalin/Paraffin, ELISA (EIA), Western Blot (WB). Western blotting: 1:100-400 Immunocytochemistry in formalin fixed cells: 1:100-500 Immunohistochemistry in formalin fixed frozen section: 1:100-500 Immunohistochemistry in paraffin section: 1:50-200 Enzyme-linked Immunosorbent Assay: 1:100-200. Researchers should empirically determine the suitability of the RANk tnfrsf11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGSEF- LI QQGSKSIPPF QEPLEVGEND SLSQCFTGTE STVDSEGCDF TEPPSRTDSM PVSPEKHLTK EIEGDSCLPW VVSSNSTDGY TGSGNTPGED HEPFPGSLKC GPLPQCAYSM GFPSEAAASM AEAGVRPQDR. It is sometimes possible for the material contained within the vial of "Receptor Activator Of Nuclear Factor Kappa B (RANk), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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