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58 results for "PARP 1 inhibitor" - showing 1-50
Structure
Z-VAD-FMK, Inhibitor (Cat# AAA578589)
Full Name
Z-VAD-FMK
Purity
99.41%
Pricing
$200/1 mg | $230/2 mg | $265/5 mg | $315/10 mg | $465/25 mg | $265/1 mL (in DMSO) | $1,815/5x25 mg
Testing Data
(Published customer image: Confirmation and in vitro characterization of Hit compounds. A) HeLa cells were treated with the ten compounds that produced the strongest reduction in pSer40/41MCM2 levels in the primary screen. Protein extracts were prepared and levels of residual pSer40/41MCM2 phosphorylation were measured by western blot analysis with the indicated antibodies. B) The same compounds were tested for their ability to inhibit CDC7 kinase activity in in vitro kinase assay. Kinase reactions were performed on a synthetic MCM2 substrate in the absence or presence of the indicated drug and reactions were run on SDS-PAGE gels. CDC7 activity on the synthetic MCM2 substrate was monitored by Western blotting with an anti-pSer108MCM2 antibody. As a control the levels of CDC7 kinase and synthetic MCM2 substrate present in each reaction were also assessed and shown to be similar in all reactions.From: FitzGerald J, Murillo LS, O'Brien G, O'Connell E, O'Connor A, et al. (2014) A High Through-Put Screen for Small Molecules Modulating MCM2 Phosphorylation Identifies Ryuvidine as an Inducer of the DNA Damage Response. PLoS ONE 9(6): e98891.)
MCM2, Monoclonal Antibody (Cat# AAA212357)
Full Name
MOUSE ANTI HUMAN MCM2
Gene Names
MCM2; BM28; CCNL1; CDCL1; cdc19; D3S3194; MITOTIN
Applications
WB
Pricing
$345/0.1 mg | $1,405/5x0.1 mg
Western Blot (WB)
(Western Blot: Cell extracts from Jurkat cells treated with 0.25mg/ml cytochrome c, using Caspase 3, Cleaved (Asp175) Pab Rb xHu|C2087-16A without preincubation (left) and preincubated with Caspase 3, Cleaved (Asp175)|C2087-16A1 as Blocking Peptide (right).)
Caspase 3, Cleaved, Inhibitor (Cat# AAA655367)
Full Name
Caspase 3, Cleaved (Asp175) (CPP-32, Apoptain, Yama, SCA-1) Blocking Peptide
Gene Names
CASP3; CPP32; SCA-1; CPP32B
Applications
EL/EIA
Purity
Purified
Purified
Purified
Pricing
$375/0.1 mg | $1,670/5x0.1 mg
Structure
Olaparib, Inhibitor (Cat# AAA575811)
Full Name
Olaparib (AZD2281, Ku-0059436)
Purity
99.88%
Pricing
$170/2 mg | $190/5 mg | $205/10 mg | $215/50 mg | $235/100 mg | $305/500 mg | $365/1 g | $260/200 mg | $1,375/5x1 g
Structure
Talazoparib, Inhibitor (Cat# AAA578816)
Full Name
Talazoparib (BMN 673)
Purity
99.42%
Pricing
$180/1 mg | $190/2 mg | $210/5 mg | $230/10 mg | $265/25 mg | $330/50 mg | $440/100 mg | $560/200 mg | $210/1 mL (in DMSO) | $2,250/5x200 mg
Structure
ME0328, Inhibitor (Cat# AAA579119)
Full Name
ME0328
Purity
98.0%
Pricing
$200/5 mg | $215/10 mg | $280/25 mg | $395/50 mg | $630/100 mg | $200/1 mL (in DMSO) | $2,565/5x100 mg
Structure
PJ34, Inhibitor (Cat# AAA578761)
Full Name
PJ34
Purity
98.0%
Pricing
$185/2 mg | $195/5 mg | $200/10 mg | $235/25 mg | $310/50 mg | $425/100 mg | $195/1 mL (in DMSO) | $1,650/5x100 mg
Niraparib, Inhibitor (Cat# AAA579557)
Full Name
Niraparib
Purity
99.9%
Pricing
$190/2 mg | $210/5 mg | $230/10 mg | $255/25 mg | $285/50 mg | $355/100 mg | $210/1 mL (in DMSO) | $1,320/5x100 mg
Structure
NMS-P118, Inhibitor (Cat# AAA3601093)
Full Name
NMS-P118
Purity
>98% (HPLC)
Pricing
$330/10 mg | $555/25 mg | $885/50 mg | $3,695/5x50 mg
Structure
Salvigenin, Inhibitor (Cat# AAA5759749)
Full Name
Salvigenin
Purity
99.17%
Pricing
$480/10 mg | $1,900/5x10 mg
Structure
NVP-BVU972, Inhibitor (Cat# AAA3607169)
Full Name
NVP-BVU972
Purity
>98% (HPLC)
Pricing
$235/2 mg | $375/10 mg | $555/25 mg | $765/50 mg | $3,175/5x50 mg
1,5-Isoquinolinediol, Inhibitor (Cat# AAA5751062)
Full Name
1,5-Isoquinolinediol
Purity
98.00%
Pricing
$205/5 mg | $205/1 mL (in DMSO) | $660/5x5 mg
Polyporenic acid C, Inhibitor (Cat# AAA5759903)
Full Name
Polyporenic acid C
Purity
98.00%
Pricing
$360/1 mg | $800/5 mg | $3,310/5x5 mg
Structure
Furanodiene, Inhibitor (Cat# AAA5760381)
Full Name
Furanodiene
Purity
98.00%
Pricing
$525/1 mg | $2,090/5x1 mg
Structure
AG-14361, Inhibitor (Cat# AAA3604072)
Full Name
AG-14361
Purity
>98% (HPLC)
Pricing
$205/2 mg | $265/5 mg | $355/10 mg | $565/25 mg | $840/50 mg | $3,475/5x50 mg
Chemical Structure
(Chemical structure of Rucaparib phosphate, a PARP Inhibitor. CAS #: 459868-92-9. Molecular Formula: C19H18FN3O * H3PO4. Molecular Weight: 421.4 g/mol.)
PARP, Inhibitor (Cat# AAA8005709)
Full Name
PARP Inhibitor
Purity
>98% (HPLC); NMR (Conforms)
Pricing
$215/5 mg | $430/25 mg | $1,695/5x25 mg | $735/5x5 mg
Zingiberen newsaponin, Inhibitor (Cat# AAA5761032)
Full Name
Zingiberen newsaponin
Purity
98.00%
Pricing
$375/1 mg | $1,395/5x1 mg
Lupiwighteone, Inhibitor (Cat# AAA5760610)
Full Name
Lupiwighteone
Purity
98.00%
Pricing
$550/5 mg | $2,170/5x5 mg
Chemical Structure
BYK 49187, Inhibitor (Cat# AAA3841059)
Full Name
BYK 49187
Purity
>98%
Pricing
$170/1 mg | $455/5 mg | $2,000/5x5 mg
Structure
AZD2461, Inhibitor (Cat# AAA3607161)
Full Name
AZD2461
Purity
>98% (HPLC)
Pricing
$200/5 mg | $215/10 mg | $240/25 mg | $295/50 mg | $360/100 mg | $1,325/5x100 mg
Structure
Veliparib dihydrochloride, Inhibitor (Cat# AAA3606543)
Full Name
Veliparib dihydrochloride
Purity
>98% (HPLC)
Pricing
$200/5 mg | $210/10 mg | $275/25 mg | $315/50 mg | $440/100 mg | $610/200 mg | $2,465/5x200 mg
Structure
BYK204165, Inhibitor (Cat# AAA5758758)
Full Name
BYK204165
Purity
99.61%
Pricing
$210/2 mg | $235/5 mg | $270/10 mg | $430/25 mg | $675/50 mg | $835/100 mg | $1,050/200 mg | $240/1 mL (in DMSO) | $4,460/5x200 mg
Structure
Amelparib hydrochloric hydrate, Inhibitor (Cat# AAA3601930)
Full Name
Amelparib hydrochloric hydrate
Purity
>98% (HPLC)
Chemical Structure
BYK 204165, Inhibitor (Cat# AAA3841058)
Full Name
BYK 204165
Purity
>98%
Pricing
$195/10 mg | $645/50 mg | $2,845/5x50 mg
Structure
Deoxypodophyllotoxin, Inhibitor (Cat# AAA5759837)
Full Name
Deoxypodophyllotoxin
Purity
98.00%
Pricing
$445/5 mg | $665/10 mg | $2,735/5x10 mg
Structure
BYK204165, Inhibitor (Cat# AAA3611108)
Full Name
BYK204165
Purity
>98% (HPLC)
Pricing
$205/2 mg | $230/5 mg | $275/10 mg | $365/25 mg | $480/50 mg | $655/100 mg | $905/200 mg | $3,790/5x200 mg
Hellebrigenin, Inhibitor (Cat# AAA5760457)
Full Name
Hellebrigenin
Purity
98.00%
Pricing
$400/5 mg | $1,520/5x5 mg
Structure
MK-4827 hydrochloride, Inhibitor (Cat# AAA3600195)
Full Name
MK-4827 hydrochloride
Purity
>98% (HPLC)
Pricing
$280/10 mg | $500/50 mg | $1,975/5x50 mg
Structure
E7449, Inhibitor (Cat# AAA3600499)
Full Name
E7449
Purity
>98% (HPLC)
Pricing
$330/10 mg | $520/25 mg | $830/50 mg | $3,440/5x50 mg
Structure
MK-4827, Inhibitor (Cat# AAA3600194)
Full Name
MK-4827
Purity
>98% (HPLC)
Pricing
$205/2 mg | $225/5 mg | $265/10 mg | $360/25 mg | $470/50 mg | $730/100 mg | $3,015/5x100 mg
Structure
MK-4827 tosylate, Inhibitor (Cat# AAA3600196)
Full Name
MK-4827 tosylate
Purity
>98% (HPLC)
Pricing
$200/2 mg | $215/5 mg | $275/10 mg | $365/25 mg | $500/50 mg | $710/100 mg | $2,915/5x100 mg
Structure
Niraparib R-enantiomer, Inhibitor (Cat# AAA5753495)
Full Name
Niraparib R-enantiomer
Purity
98.00%
Pricing
$245/2 mg | $325/5 mg | $450/10 mg | $970/50 mg | $315/1 mL (in DMSO) | $4,090/5x50 mg
Structure
BETd-260, Inhibitor (Cat# AAA5754599)
Full Name
BETd-260
Purity
98.00%
Pricing
$510/5 mg | $765/10 mg | $1,400/25 mg | $2,165/50 mg | $9,445/5x50 mg
Ferruginol, Inhibitor (Cat# AAA5760373)
Full Name
Ferruginol
Purity
98.00%
Pricing
$335/1 mg | $1,220/5x1 mg
Ergosta-4,6,8(14),22-tetraen-3-one, Inhibitor (Cat# AAA5760348)
Full Name
Ergosta-4,6,8(14),22-tetraen-3-one
Purity
98.00%
Pricing
$435/1 mg | $1,665/5x1 mg
Chemical Structure
Benzamide, Inhibitor (Cat# AAA3840325)
Full Name
Benzamide
Purity
>98%
Pricing
$300/5 mg | $510/10 mg | $975/25 mg | $4,335/5x25 mg
Chemical Structure
OUL35, Inhibitor (Cat# AAA5765147)
Full Name
OUL35
Purity
0.993
Pricing
$210/5 mg | $230/10 mg | $290/25 mg | $350/50 mg | $500/100 mg | $1,970/5x100 mg
Structure
Veliparib, Inhibitor (Cat# AAA3606542)
Full Name
Veliparib
Purity
>98% (HPLC)
Pricing
$190/5 mg | $210/10 mg | $275/25 mg | $320/50 mg | $420/100 mg | $1,610/5x100 mg
Lasiodin, Inhibitor (Cat# AAA5760575)
Full Name
Lasiodin
Purity
98.00%
Pricing
$360/1 mg | $1,325/5x1 mg
Structure
(8R,9S)-Talazoparib, Inhibitor (Cat# AAA5752805)
Full Name
(8R,9S)-Talazoparib
Purity
98.00%
Pricing
$370/1 mg | $425/5 mg | $375/1mL*10mM (in DMSO) | $1,635/5x5 mg
Structure
Structure
Olaparib, Inhibitor (Cat# AAA3605894)
Full Name
Olaparib
Purity
>98% (HPLC)
Pricing
$190/5 mg | $200/10 mg | $205/25 mg | $215/50 mg | $230/100 mg | $250/200 mg | $845/5x200 mg
Structure
Rucaparib phosphate, Inhibitor (Cat# AAA3604548)
Full Name
Rucaparib phosphate
Purity
>98% (HPLC)
Pricing
$190/2 mg | $210/5 mg | $245/10 mg | $310/25 mg | $360/50 mg | $485/100 mg | $730/200 mg | $3,015/5x200 mg
Chemical Structure
S-P118, Inhibitor (Cat# AAA5764888)
Full Name
S-P118
Purity
0.9887
Pricing
$225/2 mg | $250/5 mg | $325/10 mg | $490/25 mg | $675/50 mg | $950/100 mg | $1,355/200 mg | $265/1 mL (in DMSO) | $5,825/5x200 mg
Structure
Talazoparib tosylate, Inhibitor (Cat# AAA5755581)
Full Name
Talazoparib tosylate
Purity
98.00%
Pricing
$235/2 mg | $280/5 mg | $345/10 mg | $685/50 mg | $1,065/100 mg | $1,570/200 mg | $305/1mL*10mM (in DMSO) | $6,770/5x200 mg
Structure
Dipyrithione, Inhibitor (Cat# AAA5758822)
Full Name
Dipyrithione
Purity
99.86%
Pricing
$195/5 mg | $615/5x5 mg
Structure
Rucaparib Camsylate, Inhibitor (Cat# AAA5755489)
Full Name
Rucaparib Camsylate
Pricing
$200/2 mg | $210/5 mg | $255/10 mg | $330/25 mg | $435/50 mg | $680/100 mg | $230/1 mL (in DMSO) | $2,795/5x100 mg
Lucidenic acid B, Inhibitor (Cat# AAA5760599)
Full Name
Lucidenic acid B
Purity
98.00%
Pricing
$360/1 mg | $800/5 mg | $3,310/5x5 mg
Buddlejasaponin IV, Inhibitor (Cat# AAA5760199)
Full Name
Buddlejasaponin IV
Purity
98.00%
Pricing
$380/1 mg | $1,410/5x1 mg
Chemical Structure
4-HQN, Inhibitor (Cat# AAA3841057)
Full Name
4-HQN
Purity
>98%
Pricing
$215/50 mg | $125/100 mg | $925/5x50 mg
