Structure

Deoxypodophyllotoxin, Inhibitor

Deoxypodophyllotoxin

Purity

98.00%

Synonyms

Deoxypodophyllotoxin; inhibitor

Ordering
Cat. Num. AAA5759837 For Research Use Only!

Purity/Purification

98.00%

Form/Format

Solid. Powder

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C22H22O7

SMILES

[H][C@]12COC(=O)[C@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1C2

CAS Number

19186-35-7

Target & IC50

Bcl-2
Caspase
PARP
microtubule
Autophagy
Apoptosis

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Structure

Related Product Information for Deoxypodophyllotoxin, inhibitor

Deoxypodophyllotoxin shows cytotoxic, antineoplastic, antitumor, insecticidal, anti-angiogenic, vascular disrupting, insecticidal, antiviral, and anti-inflammatory activities.

Product Categories/Family for Deoxypodophyllotoxin, inhibitor

Apoptosis; BCL; Cytoskeletal Signaling; Autophagy

References

Kim SH, et al. Deoxypodophyllotoxin induces cytoprotective autophagy against apoptosis via inhibition of PI3K/AKT/mTOR pathway in osteosarcoma U2OS cells. Pharmacol Rep. 2017 Oct;69(5):878-884.
Kim SH, et al. Deoxypodophyllotoxin induces cytoprotective autophagy against apoptosis via inhibition of PI3K/AKT/mTOR pathway in osteosarcoma U2OS cells. Pharmacol Rep. 2017 Oct;69(5):878-884.
Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects. Int J Biochem Cell Biol. 2013 Aug;45(8):1710-9.
Deoxypodophyllotoxin exerts both anti-angiogenic and vascular disrupting effects. Int J Biochem Cell Biol. 2013 Aug;45(8):1710-9.
Pharmacological effect of deoxypodophyllotoxin: a medicinal agent of plant origin, on mammalian neurons.Neurotoxicology. 2010 Dec;31(6):680-6.
Insecticidal activity of deoxypodophyllotoxin, isolated from Juniperus sabina L, and related lignans against larvae of Pieris rapae L.Pest Manag Sci. 2004 Nov;60(11):1131-6.

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Product Notes

The Deoxypodophyllotoxin (Catalog #AAA5759837) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Deoxypodophyllotoxin, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Deoxypodophyllotoxin, Inhibitor