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SDS-PAGE

Trypsin 2 / PRSS2 Recombinant Protein | PRSS2 recombinant protein

Recombinant Mouse Trypsin 2 / PRSS2 Protein (His tag)

Gene Names
Prss2; Ta; TRY8; TRYP; Try2; Tesp4
Purity
> 92 % as determined by SDS-PAGE
Synonyms
Trypsin 2 / PRSS2; Recombinant Mouse Trypsin 2 / PRSS2 Protein (His tag); Prss2; TRY8; TRYP; Ta; Tesp4; Try2; PRSS2 recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 92 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.5
Sequence Length
246
Application Notes
The recombinant pro form of mouse PRSS2 comprises 242 amino acids and has a predicted molecular mass of 26.2 kDa. The apparent molecular mass of rm PRSS2 is approximately 32 kDa in SDS-PAGE under reducing conditions.
Predicted N Terminal
Phe 16
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for PRSS2 recombinant protein
Background: Mouse Trypsin-2, also known as Trypsin II, Anionic trypsinogen, Serine protease 2, PRSS2 and TRY2, is a secreted protein which belongs to the trypsin serine protease family including Trypsin, PRSS1, PRSS2 and PRSS3. It consists of a signal peptide (residues 1-15), a pro region (residues 16-23), and a proteolytically active mature chain (residues 24-247). PRSS2 contains one peptidase S1 domain. It is secreted into the duodenum, hydrolysing peptides into their smaller building blocks, which is necessary for the uptake of protein in the food. It is secreted by the pancreas in the form of inactive zymogen, trypsinogen and cleaved to its active form in the small intestine when the pancreas is stimulated by cholecystokinin through the common activation mechanism.

Description: A DNA sequence encoding the mouse PRSS2 (NP_033456.1) precursor (Met 1-Asn 246) was expressed, with a C-terminal polyhistidine tag.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
26,204 Da
NCBI Official Full Name
anionic trypsin-2
NCBI Official Synonym Full Names
protease, serine 2
NCBI Official Symbol
Prss2
NCBI Official Synonym Symbols
Ta; TRY8; TRYP; Try2; Tesp4
NCBI Protein Information
anionic trypsin-2
UniProt Protein Name
Anionic trypsin-2
Protein Family
UniProt Gene Name
Prss2
UniProt Synonym Gene Names
Try2

Uniprot Description

trypsin 2: In the ileum, may be involved in defensin processing, including DEFA5. Belongs to the peptidase S1 family.

Protein type: Calcium-binding; Cell adhesion; EC 3.4.21.4; Extracellular matrix; Protease; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 6|6 B1

Cellular Component: extracellular region; extracellular space

Molecular Function: calcium ion binding; serine-type endopeptidase activity

Biological Process: collagen catabolic process; digestion; proteolysis; response to caffeine; response to nicotine

Research Articles on PRSS2

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Product Notes

The PRSS2 prss2 (Catalog #AAA2547011) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant pro form of mouse PRSS2 comprises 242 amino acids and has a predicted molecular mass of 26.2 kDa. The apparent molecular mass of rm PRSS2 is approximately 32 kDa in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the PRSS2 prss2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Trypsin 2 / PRSS2, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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