Western Blot (WB)
(EXTL3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the EXTL3 antibody detected the EXTL3 protein (arrow).)
Rabbit anti-Human EXTL3 Polyclonal Antibody | anti-EXTL3 antibody
EXTL3, NT (EXTL3, EXTL1L, EXTR1, KIAA0519, Exostosin-like 3, EXT-related protein 1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, Multiple exostosis-like protein 3, Putative tumor su
Gene Names
EXTL3; RPR; BOTV; REGR; EXTR1; EXTL1L
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
EXTL3; Polyclonal Antibody; NT (EXTL3; EXTL1L; EXTR1; KIAA0519; Exostosin-like 3; EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; Multiple exostosis-like protein 3; Putative tumor su; Putative tumor suppressor protein EXTL3; anti-EXTL3 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Applicable Applications for anti-EXTL3 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes
IHC: 1:10-50
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
FLISA: 1:1,000
WB: 1:100-500
Applications are based on unconjugated antibody.
Immunogen
EXTL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 352-382 amino acids from the N-terminal region of human EXTL3.
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Western Blot (WB)
(EXTL3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the EXTL3 antibody detected the EXTL3 protein (arrow).)
Western Blot (WB)
(EXTL3 Antibody (N-term) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the EXTL3 antibody detected the EXTL3 protein (arrow).)
Immunohistochemistry (IHC)
(EXTL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EXTL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(EXTL3 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human esophageal carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EXTL3 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Related Product Information for anti-EXTL3 antibody
EXTL3 is probable glycosyltransferase (By similarity).
Product Categories/Family for anti-EXTL3 antibody
References
Kaidonis, X., et al. Eur. J. Hum. Genet. 18(2):194-199(2010). Pata, G., et al. J Surg Oncol 100(6):520-522(2009). Levetan, C.S., et al. Endocr Pract 14(9):1075-1083(2008). Karibe, T., et al. J. Pathol. 216(1):32-42(2008). Wu, C., et al. Proteomics 7(11):1775-1785(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
104,749 Da
NCBI Official Full Name
exostosin-like 3
NCBI Official Synonym Full Names
exostosin-like glycosyltransferase 3
NCBI Official Symbol
EXTL3
NCBI Official Synonym Symbols
RPR; BOTV; REGR; EXTR1; EXTL1L
NCBI Protein Information
exostosin-like 3; reg receptor; EXT-related 1; exostosin tumor-like 3; exostoses (multiple)-like 3; putative tumor suppressor protein EXTL3; hereditary multiple exostoses gene isolog; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransfer
UniProt Protein Name
Exostosin-like 3
Protein Family
UniProt Gene Name
EXTL3
UniProt Synonym Gene Names
EXTL1L; EXTR1; KIAA0519
UniProt Entry Name
EXTL3_HUMAN
Uniprot Description
EXTL3: Probable glycosyltransferase. Belongs to the glycosyltransferase 47 family.
Protein type: Membrane protein, integral; Transferase; EC 2.4.1.223; Glycan Metabolism - heparan sulfate biosynthesis
Chromosomal Location of Human Ortholog: 8p21
Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane
Molecular Function: metal ion binding; glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity
Biological Process: glycosaminoglycan biosynthetic process; cellular protein metabolic process; unfolded protein response, activation of signaling protein activity; unfolded protein response; heparan sulfate proteoglycan biosynthetic process; positive regulation of cell growth
Similar Products
Product Notes
The EXTL3 extl3 (Catalog #AAA6297208) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The EXTL3, NT (EXTL3, EXTL1L, EXTR1, KIAA0519, Exostosin-like 3, EXT-related protein 1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, Multiple exostosis-like protein 3, Putative tumor su reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's EXTL3 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), FLISA, Western Blot (WB). IHC: 1:10-50 FLISA: 1:1,000 WB: 1:100-500 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the EXTL3 extl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EXTL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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