Testing Data
Rabbit TLR11 Polyclonal Antibody | anti-TLR11 antibody
TLR11 Antibody
Gene Names
Tlr11; Gm287
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Affinity purified
Synonyms
TLR11; Polyclonal Antibody; TLR11 Antibody; Toll-like receptor 11; anti-TLR11 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
931
Applicable Applications for anti-TLR11 antibody
Western Blot (WB)
Application Notes
Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~70-90 kDa of TLR11 in Jurkat cell lysate. Reactivity to other species has not been tested.
Immunogen
Synthetic peptide surrounding amino acid 793 of mouse TLR11
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-TLR11 antibody
Background: The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors.TLR11 is activated by uropathogenic bacteria and may play a role in preventing urogenital infections.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
105,873 Da
NCBI Official Full Name
toll-like receptor 11
NCBI Official Synonym Full Names
toll-like receptor 11
NCBI Official Symbol
Tlr11
NCBI Official Synonym Symbols
Gm287
NCBI Protein Information
toll-like receptor 11
UniProt Protein Name
Toll-like receptor 11
Protein Family
UniProt Gene Name
Tlr11
UniProt Synonym Gene Names
Gm287
UniProt Entry Name
TLR11_MOUSE
Uniprot Description
Tlr11: Participates in the innate immune response to microbial agents. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Belongs to the Toll-like receptor family.
Cellular Component: membrane; integral to membrane
Molecular Function: protein binding; transmembrane receptor activity
Biological Process: MyD88-dependent toll-like receptor signaling pathway; regulation of cytokine secretion; response to bacterium; immune system process; innate immune response; signal transduction; inflammatory response; toll-like receptor 11 signaling pathway; positive regulation of inflammatory response
Research Articles on TLR11
Similar Products
Product Notes
The TLR11 tlr11 (Catalog #AAA840654) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TLR11 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TLR11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~70-90 kDa of TLR11 in Jurkat cell lysate. Reactivity to other species has not been tested. Researchers should empirically determine the suitability of the TLR11 tlr11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TLR11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
