Western Blot (WB)
(Detection of Human and Rat PPP1R9B by Western Blot. Western blot shows lysates of human brain tissue and rat brain tissue. PVDF Membrane was probed with 1ug/ml of Human/Rat PPP1R9B Antigen Affinitypurified Polyclonal Antibody followed by HRPconjugated Sheep IgG Secondary Antibody. Specific bands were detected for PPP1R9B at approximately 90120kD (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.)
Sheep anti-Human Spinophilin Polyclonal Antibody
Spinophilin (Neurabin-II, PPP1R9B)
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Dilution: Western Blot: 1ug/ml
Western Blot (WB)
(Detection of Human and Rat PPP1R9B by Western Blot. Western blot shows lysates of human brain tissue and rat brain tissue. PVDF Membrane was probed with 1ug/ml of Human/Rat PPP1R9B Antigen Affinitypurified Polyclonal Antibody followed by HRPconjugated Sheep IgG Secondary Antibody. Specific bands were detected for PPP1R9B at approximately 90120kD (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.)
Western Blot (WB)
(Detection of Human and Rat PPP1R9B by Western Blot. Western blot shows lysates of human brain tissue and rat brain tissue. PVDF Membrane was probed with 1ug/ml of Human/Rat PPP1R9B Antigen Affinitypurified Polyclonal Antibody followed by HRPconjugated Sheep IgG Secondary Antibody. Specific bands were detected for PPP1R9B at approximately 90120kD (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.)
NCBI and Uniprot Product Information
Uniprot Description
Spinophilin: actin-binding regulatory subunit of protein phosphatase 1 (PP1). The actin-binding domain of spinophilin is necessary and sufficient for targeting of spinophilin to dendrites and dendritic spines. May play a role in establishing a signaling complex for dopaminergic neurotransmission through D2 receptors by linking receptors downstream signaling molecules and the actin cytoskeleton. Interacts with p14-ARF. Contains one PDZ/DHR domain.
Protein type: Adaptor/scaffold; Protein phosphatase, regulatory subunit
Cellular Component: nucleoplasm; cortical actin cytoskeleton; cytoskeleton; cell projection; membrane; lamellipodium; cytoplasm; plasma membrane; synapse; intracellular; cell junction; nucleus; filopodium
Molecular Function: protein binding; actin binding; protein phosphatase 1 binding
Biological Process: regulation of synaptic transmission; nervous system development; regulation of protein amino acid phosphorylation; cell migration; filopodium formation; multicellular organismal development; dendrite development; calcium-mediated signaling; actin filament organization; negative regulation of cell growth; cell differentiation; actin cytoskeleton organization and biogenesis; regulation of cell proliferation
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Product Notes
The Spinophilin (Catalog #AAA6002691) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Spinophilin (Neurabin-II, PPP1R9B) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Spinophilin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Suitable for use in Western Blot. Dilution: Western Blot: 1ug/ml. Researchers should empirically determine the suitability of the Spinophilin for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Spinophilin, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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