Western Blot (WB)
(Western blot analysis of SIPA1L3 in SK-N-SH lysate with SIPA1L3 antibody at 1 ug/mL.)
Rabbit SIPA1L3 Polyclonal Antibody | anti-SIPA1L3 antibody
SIPA1L3 Antibody
Gene Names
SIPA1L3; SPAL3
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
SIPA1L3; Polyclonal Antibody; SIPA1L3 Antibody; Signal-induced proliferation associated-like protein 3; SPAL3; anti-SIPA1L3 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
1781
Applicable Applications for anti-SIPA1L3 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 15 amino acid peptide from near the amino terminus of human SIPA1L3.
Target Name
SIPA1L3
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SIPA1L3 in SK-N-SH lysate with SIPA1L3 antibody at 1 ug/mL.)
Western Blot (WB)
(Western blot analysis of SIPA1L3 in SK-N-SH lysate with SIPA1L3 antibody at 1 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SIPA1L3 in human brain tissue with SIPA1L3 antibody at 5 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SIPA1L3 in human brain tissue with SIPA1L3 antibody at 5 ug/mL.)
Related Product Information for anti-SIPA1L3 antibody
Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.
Product Categories/Family for anti-SIPA1L3 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
194,610 Da
NCBI Official Full Name
signal-induced proliferation-associated 1-like protein 3
NCBI Official Synonym Full Names
signal-induced proliferation-associated 1 like 3
NCBI Official Symbol
SIPA1L3
NCBI Official Synonym Symbols
SPAL3
NCBI Protein Information
signal-induced proliferation-associated 1-like protein 3
UniProt Protein Name
Signal-induced proliferation-associated 1-like protein 3
Protein Family
UniProt Gene Name
SIPA1L3
UniProt Synonym Gene Names
KIAA0545; SPAL3; SIPA1-like protein 3
UniProt Entry Name
SI1L3_HUMAN
Uniprot Description
SIPA1L3:
Protein type: GAPs, Ras; GAPs
Chromosomal Location of Human Ortholog: 19q13.13
Cellular Component: extracellular space
Molecular Function: GTPase activator activity
Biological Process: regulation of small GTPase mediated signal transduction; hemopoietic progenitor cell differentiation; positive regulation of GTPase activity
Research Articles on SIPA1L3
Similar Products
Product Notes
The SIPA1L3 sipa1l3 (Catalog #AAA9413707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SIPA1L3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SIPA1L3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SIPA1L3 sipa1l3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SIPA1L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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