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Immunohistochemistry (IHC) (Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE))

Rabbit anti-Mouse, Human DECR1 Polyclonal Antibody | anti-DECR1 antibody

Anti-DECR1 Antibody (aa1-335) IHC-plus

Gene Names
DECR1; DECR; NADPH; SDR18C1
Reactivity
Mouse, Human
Applications
Immunohistochemistry, Immunocytochemistry, Western Blot
Purity
Immunoaffinity purified
Synonyms
DECR1; Polyclonal Antibody; Anti-DECR1 Antibody (aa1-335) IHC-plus; Rabbit Polyclonal to Human DECR1; Human DECR1; 2; 4-dienoyl-coa reductase; 4-enoyl-CoA reductase [NADPH]; 4-enoyl-CoA reductase; DECR; NADPH; SDR18C1; anti-DECR1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Human
Clonality
Polyclonal
Specificity
Human DECR1
Purity/Purification
Immunoaffinity purified
Form/Format
0.1 M Tris-glycine, pH 7.0, 10% glycerol, 0.01% Thimerosal
Concentration
1 mg/ml (varies by lot)
Sequence Length
335
Applicable Applications for anti-DECR1 antibody
Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Western Blot (WB)
Application Notes
ICC (1:100 - 1:1000)
IHC-P (5 ug/ml)
WB (1:5000 - 1:20000)
Immunogen
DECR1 antibody was raised against recombinant fragment corresponding to a region within amino acids 1 and 335 of DECR1 (SwissProt Q16698). Percent identity by BLAST analysis: Human (100%); Rat (82%).
Immunogen Description
Recombinant fragment corresponding to a region within amino acids 1 and 335 of DECR1 (SwissProt Q16698). Percent identity by BLAST analysis: Human (100%); Rat (82%).
Immunogen Type
Recombinant protein
Antigen Modification
aa1-335
Target Species
Human
Preparation and Storage
Keep as concentrated solution. Aliquot and store at -20 degree C or below. Avoid multiple freeze-thaw cycles.

Immunohistochemistry (IHC)

(Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE))

Immunohistochemistry (IHC) (Human Kidney: Formalin Fixed, Paraffin Embedded (FFPE))

Immunohistochemistry (IHC)

(Human Liver: Formalin Fixed, Paraffin Embedded (FFPE))

Immunohistochemistry (IHC) (Human Liver: Formalin Fixed, Paraffin Embedded (FFPE))

Immunocytochemistry (ICC)

(Immunofluorescence of paraformaldehyde-fixed HeLa using DECR1 antibody at 1:200 dilution.)

Immunocytochemistry (ICC) (Immunofluorescence of paraformaldehyde-fixed HeLa using DECR1 antibody at 1:200 dilution.)

Western Blot (WB)

(Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. DECR1 antibody diluted at 1:10000.)

Western Blot (WB) (Sample (30 ug of whole cell lysate). A: Hep G2. 10% SDS PAGE. DECR1 antibody diluted at 1:10000.)

Western Blot (WB)

(Sample (20 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. DECR1 antibody diluted at 1:10000.)

Western Blot (WB) (Sample (20 ug of whole cell lysate). A: mouse liver. 10% SDS PAGE. DECR1 antibody diluted at 1:10000.)
Related Product Information for anti-DECR1 antibody
DECR1 Antibody, 2,4-dienoyl-coa reductase Antibody, 4-enoyl-CoA reductase [NADPH] Antibody, 4-enoyl-CoA reductase Antibody, DECR Antibody, NADPH Antibody, SDR18C1 Antibody Description: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
34,994 Da
NCBI Official Full Name
2,4-dienoyl-CoA reductase, mitochondrial
NCBI Official Synonym Full Names
2,4-dienoyl-CoA reductase 1, mitochondrial
NCBI Official Symbol
DECR1
NCBI Official Synonym Symbols
DECR; NADPH; SDR18C1
NCBI Protein Information
2,4-dienoyl-CoA reductase, mitochondrial
UniProt Protein Name
2,4-dienoyl-CoA reductase, mitochondrial
Protein Family
UniProt Gene Name
DECR1
UniProt Synonym Gene Names
DECR; SDR18C1; 4-enoyl-CoA reductase [NADPH]
UniProt Entry Name
DECR_HUMAN

NCBI Description

This gene encodes an accessory enzyme which participates in the beta-oxidation and metabolism of unsaturated fatty enoyl-CoA esters. [provided by RefSeq, Jul 2008]

Uniprot Description

DECR1: Auxiliary enzyme of beta-oxidation. It participates in the metabolism of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3- enoyl-CoA. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2,4-dienoyl-CoA reductase subfamily.

Protein type: Oxidoreductase; EC 1.3.1.34; Mitochondrial

Chromosomal Location of Human Ortholog: 8q21.3

Cellular Component: cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm; nucleus

Molecular Function: 2,4-dienoyl-CoA reductase (NADPH) activity; oxidoreductase activity, acting on NADH or NADPH

Biological Process: cellular lipid metabolic process; fatty acid beta-oxidation; protein homotetramerization

Research Articles on DECR1

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Product Notes

The DECR1 decr1 (Catalog #AAA249632) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-DECR1 Antibody (aa1-335) IHC-plus reacts with Mouse, Human and may cross-react with other species as described in the data sheet. AAA Biotech's DECR1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunocytochemistry (ICC), Western Blot (WB). ICC (1:100 - 1:1000) IHC-P (5 ug/ml) WB (1:5000 - 1:20000). Researchers should empirically determine the suitability of the DECR1 decr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DECR1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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