Western Blot (WB)
(Western blot analysis of SLFN12 in SK-N-SH cell lysate with SLFN12 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Rabbit anti-Human SLFN12 Polyclonal Antibody | anti-SLFN12 antibody
SLFN12 Antibody
Gene Names
SLFN12; SLFN3
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity chromatography purified via peptide column
Synonyms
SLFN12; Polyclonal Antibody; SLFN12 Antibody; Schlafen family member 12; SLFN3; anti-SLFN12 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
578
Applicable Applications for anti-SLFN12 antibody
ELISA (EIA), Western Blot (WB)
Immunogen Type
Peptide
Immunogen Description
Raised against a 12 amino acid peptide from near the carboxy terminus human SLFN12.
Target Name
SLFN12
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SLFN12 in SK-N-SH cell lysate with SLFN12 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB)
(Western blot analysis of SLFN12 in SK-N-SH cell lysate with SLFN12 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.)
Related Product Information for anti-SLFN12 antibody
Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.
Product Categories/Family for anti-SLFN12 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
66,972 Da
NCBI Official Full Name
schlafen family member 12
NCBI Official Synonym Full Names
schlafen family member 12
NCBI Official Symbol
SLFN12
NCBI Official Synonym Symbols
SLFN3
NCBI Protein Information
schlafen family member 12
UniProt Protein Name
Schlafen family member 12
Protein Family
UniProt Gene Name
SLFN12
UniProt Entry Name
SLN12_HUMAN
Uniprot Description
SLFN12: Belongs to the Schlafen family.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 17q12
Molecular Function: ATP binding
Research Articles on SLFN12
Similar Products
Product Notes
The SLFN12 slfn12 (Catalog #AAA9409939) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SLFN12 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's SLFN12 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). Researchers should empirically determine the suitability of the SLFN12 slfn12 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SLFN12, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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